Find hotels in Muscatine, IA from ￥8,897

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Dec 11 - Dec 12
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Dec 12 - Dec 13
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Dec 12 - Dec 14
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Dec 19 - Dec 21

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Our top choices for Muscatine hotels

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AmericInn by Wyndham Muscatine

AmericInn by Wyndham Muscatine

AmericInn by Wyndham Muscatine
2.5 star property
Muscatine
7.6 out of 10, Good, (423)
"Even for a cheap motel it was bad…didn’t expect much but still disappointed. Won’t stay there next year "
United States
Patrick
The price is ￥12,576
￥14,085 total
includes taxes & fees
Dec 21 - Dec 22
AmericInn by Wyndham Muscatine
Reception
Hampton Inn Muscatine

Hampton Inn Muscatine

Hampton Inn Muscatine
2.5 star property
Muscatine
8.4 out of 10, Very Good, (462)
"Nice stay"
United States
Bradlee Dean
The price is ￥14,203
￥15,907 total
includes taxes & fees
Dec 28 - Dec 29
Hampton Inn Muscatine
Suite, Multiple Beds, Non Smoking | Iron/ironing board, free WiFi, bed sheets
Comfort Inn Muscatine near Hwy 61

Comfort Inn Muscatine near Hwy 61

Comfort Inn Muscatine near Hwy 61
2.5 star property
Muscatine
7.8 out of 10, Good, (214)
"great room, best breakfast each morning. Made my vacation very enjoyable."
United States
RICHARD
The price is ￥11,054
￥12,381 total
includes taxes & fees
Dec 26 - Dec 27
Comfort Inn Muscatine near Hwy 61
Reception
Best Western Muscatine / Pearl City Hotel

Best Western Muscatine / Pearl City Hotel

Best Western Muscatine / Pearl City Hotel
2.5 star property
Muscatine
8.6 out of 10, Excellent, (499)
"Best service "
United States
Hector
The price is ￥13,995
￥15,675 total
includes taxes & fees
Dec 14 - Dec 15
Best Western Muscatine / Pearl City Hotel
48-inch flat-screen TV with cable channels, TV
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
4.0 star property
Muscatine
9.6 out of 10, Exceptional, (277)
"Great Hotel. The restaurant, Maxwell's was very good."
United States
Dennis
The price is ￥26,320
￥29,478 total
includes taxes & fees
Jan 9 - Jan 10, 2026
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
In-room safe, desk, free cribs/infant beds, rollaway beds
Super 8 by Wyndham Muscatine

Super 8 by Wyndham Muscatine

Super 8 by Wyndham Muscatine
2.0 star property
Muscatine
6.2 out of 10, (278)
"Staff was nice, let me check in a little early, quiet, comfortable bed."
United States
Mark
The price is ￥9,928
￥11,119 total
includes taxes & fees
Dec 17 - Dec 18
Super 8 by Wyndham Muscatine
Reception
The Sage Hotel

The Sage Hotel

The Sage Hotel
2.0 star property
Muscatine
6.8 out of 10, (55)
"Awesome "
United States
Dauda
The Sage Hotel
2 bars/lounges
Hyatt House East Moline Quad Cities

Hyatt House East Moline Quad Cities

Hyatt House East Moline Quad Cities
3.0 star property
East Moline
9.2 out of 10, Wonderful, (1001)
"The room was very clean and the staff were amazing. The view of the river was very relaxing as well. "
United States
Dara
The price is ￥14,386
￥16,110 total
includes taxes & fees
Dec 14 - Dec 15
Hyatt House East Moline Quad Cities
Free daily buffet breakfast
Wyndham Moline on John Deere Commons

Wyndham Moline on John Deere Commons

Wyndham Moline on John Deere Commons
3.5 star property
Moline
9.0 out of 10, Wonderful, (1219)
"Clean room , breakfast was great "
United States
Charles
The price is ￥13,954
￥15,764 total
includes taxes & fees
Dec 18 - Dec 19
Wyndham Moline on John Deere Commons
Free daily continental breakfast
Quality Inn & Suites Moline - Quad Cities

Quality Inn & Suites Moline - Quad Cities

Quality Inn & Suites Moline - Quad Cities
2.5 star property
Moline
7.6 out of 10, Good, (556)
"Clean room and excellent staff "
United States
sheila
The price is ￥7,916
￥8,944 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Quality Inn & Suites Moline - Quad Cities
Cocktail bar
Hyatt Place East Moline Quad Cities

Hyatt Place East Moline Quad Cities

Hyatt Place East Moline Quad Cities
3.0 star property
East Moline
9.2 out of 10, Wonderful, (990)
"We really appreciate it when you have free shuttle to Rust Belt. We always stay here. Rooms are great and staff is friendly. Restaurants has very good food"
United States
ANGELA
The price is ￥15,753
￥17,640 total
includes taxes & fees
Dec 14 - Dec 15
Hyatt Place East Moline Quad Cities
Reception
The Axis Moline Hotel, Tapestry Collection by Hilton

The Axis Moline Hotel, Tapestry Collection by Hilton

The Axis Moline Hotel, Tapestry Collection by Hilton
3.5 star property
Moline
9.4 out of 10, Exceptional, (389)
"Great stay."
United States
John
The price is ￥20,305
￥22,941 total
includes taxes & fees
Dec 18 - Dec 19
The Axis Moline Hotel, Tapestry Collection by Hilton
Exterior
La Quinta Inn by Wyndham Moline Airport

La Quinta Inn by Wyndham Moline Airport

La Quinta Inn by Wyndham Moline Airport
3.0 star property
Moline
6.4 out of 10, (1001)
"The staff was really nice"
United States
jason
The price is ￥7,810
￥8,823 total
includes taxes & fees
Dec 26 - Dec 27
La Quinta Inn by Wyndham Moline Airport
43-inch LED TV with cable channels, Netflix, streaming services
Days Inn By Wyndham Davenport

Days Inn By Wyndham Davenport

Days Inn By Wyndham Davenport
2.0 star property
Davenport
8.0 out of 10, Very Good, (376)
"Decent stay"
United States
Christopher
The price is ￥8,970
￥10,046 total
includes taxes & fees
Dec 21 - Dec 22
Days Inn By Wyndham Davenport
Desk, blackout drapes, iron/ironing board, free WiFi
La Quinta Inn by Wyndham Davenport & Conference Center

La Quinta Inn by Wyndham Davenport & Conference Center

La Quinta Inn by Wyndham Davenport & Conference Center
3.0 star property
Davenport
7.4 out of 10, Good, (1000)
"Was a good place to stay"
United States
Ed
The price is ￥9,089
￥10,180 total
includes taxes & fees
Jan 1 - Jan 2, 2026
La Quinta Inn by Wyndham Davenport & Conference Center
Free daily buffet breakfast
Best Western Airport Inn

Best Western Airport Inn

Best Western Airport Inn
2.5 star property
Moline
8.2 out of 10, Very Good, (1001)
"Comfortable place to stay and great management thank you "
United States
Jason
The price is ￥9,172
￥10,362 total
includes taxes & fees
Dec 14 - Dec 15
Best Western Airport Inn
Indoor pool, outdoor pool
Stoney Creek Hotel Quad Cities - Moline

Stoney Creek Hotel Quad Cities - Moline

Stoney Creek Hotel Quad Cities - Moline
2.5 star property
Moline
8.4 out of 10, Very Good, (1081)
"Front desk staff were friendly very helpful and the room was clean and plenty of parking in area."
United States
Perry
Stoney Creek Hotel Quad Cities - Moline
Exterior
Holiday Inn Express Moline - Quad Cities Area by IHG

Holiday Inn Express Moline - Quad Cities Area by IHG

Holiday Inn Express Moline - Quad Cities Area by IHG
2.5 star property
Moline
9.4 out of 10, Exceptional, (707)
"Housekeeping and breakfast area management were great"
United States
Kim
The price is ￥15,107
￥17,069 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express Moline - Quad Cities Area by IHG
Exterior
Isle Casino Hotel - Bettendorf

Isle Casino Hotel - Bettendorf

Isle Casino Hotel - Bettendorf
3.0 star property
Bettendorf
8.4 out of 10, Very Good, (1003)
"great place to stay"
United States
Jill
The price is ￥16,353
￥20,581 total
includes taxes & fees
Dec 14 - Dec 15
Isle Casino Hotel - Bettendorf
Room, 1 King Bed, Accessible, Non Smoking | Premium bedding, down comforters, desk, blackout drapes
Comfort Inn Davenport East - Bettendorf

Comfort Inn Davenport East - Bettendorf

Comfort Inn Davenport East - Bettendorf
2.5 star property
Davenport
9.2 out of 10, Wonderful, (165)
"Clean room, comfortable beds, very friendly staff, very affordable. "
United States
Alicia
The price is ￥10,142
￥11,360 total
includes taxes & fees
Dec 18 - Dec 19
Comfort Inn Davenport East - Bettendorf
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Muscatine attractions

Doing photography as a hobby. I took this 1st day of 2019. It was cloudy and a little bit chilly.
Photo by Carlos Lima
Open Photo by Carlos Lima

Wildcat Den State Park

Explore dramatic sandstone bluffs and the historic Pine Creek Grist Mill, dating to 1848, at this scenic park. Hike through diverse terrain with views of unique rock formations like Steamboat Rock and Devil's Punch Bowl.
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Iowa, heartland, fall, train trestle, railroad tracks, river, clouds, sky, blue, fields, rivers, midwest, views

Riverside Park

4.0/5 (42 reviews)
Riverside Park offers stunning Mississippi River views and a captivating illuminated bridge at night. Stroll along waterfront trails or cool off at the interactive Mississippi Mist Fountain during warm months.
See properties

Learn more about Muscatine

Stroll along the Mississippi riverfront to spot bald eagles and watch riverboats glide by. Explore local history at the Pearl Button Museum, then sample wines at the family-owned Ardon Creek Winery.

See all hotels in Muscatine
Confluence of Mississippi and Wisconsin Rivers, Iowa

Top Muscatine Hotel Reviews

AmericInn by Wyndham Muscatine

AmericInn by Wyndham Muscatine

10/10 Excellent
"The breakfast was good but it was all carbs it would of been good to do scramble eggs. But other than that ir was very good."
Rhonda 2-night trip
Posted 3 days ago
AmericInn by Wyndham Muscatine

More cheap stays in Muscatine

Days Inn By Wyndham Davenport

Days Inn By Wyndham Davenport

400 Jason Way Ct Suite DA Davenport IA
The price is ￥8,970 per night from Dec 21 to Dec 22
￥8,970
￥10,046 total
Dec 21 - Dec 22
includes taxes & fees
7.8/10 Good! (373 reviews)

Frequently asked questions

What's the best place for a stay in Muscatine?
Strawberry Farm Bed & Breakfast is a favorite with Expedia customers. This B&B offers free breakfast and free parking. Reviews from our site also recommend Hampton Inn Muscatine and Best Western Muscatine / Pearl City Hotel as top choices for your trip. See all available top hotels, or vacation rentals in Muscatine.
What's the top vacation rental in Muscatine?
Lucy's House Single Family Bungalow: This vacation home rental outside of Muscatine is located on a river and has a patio, a garden, and air-conditioning to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. Make the most of the books in this rental home to help you unwind. See all vacation rentals in Muscatine.
If I need to cancel my hotel reservation in Muscatine, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Muscatine.
Where can I learn more about changing or cancelling my trip to Muscatine?
For more information about changing or cancelling your trip to Muscatine, head over to our customer service page.
What's the best place to stay when traveling with kids to Muscatine?
Super 8 by Wyndham Muscatine is a hotel with free parking and free breakfast, and it's a top choice on Expedia for families. The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel is another good option for your family trip. Kids of all ages will also enjoy a visit to Muscatine Aquatic Center. Find more child-friendly accommodations in Muscatine.
What is the favorite LGBTQ-friendly accommodation in Muscatine?
Hampton Inn Muscatine is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel is another good option for your trip. See all available hotels listed as LGBTQ-friendly in Muscatine.
What's the best pet-friendly place to stay in Muscatine?
AmericInn by Wyndham Muscatine is a top dog-friendly hotel, and offers an indoor pool along with free WiFi for its human guests. Two other good options for you and your pet's trip include Hampton Inn Muscatine and Best Western Muscatine / Pearl City Hotel. See more pet-friendly hotel accommodations in Muscatine.
What's the best place to stay close to Geneva Golf and Country Club?
Strawberry Farm Bed & Breakfast is one of the top choices for your stay based on our traveler data, and this 3-star B&B offers free breakfast and free parking. It's located just a short 0.8 mi (1.3 km) from Geneva Golf and Country Club. Other good options within a few miles include Best Western Pearl City Inn and Comfort Inn Muscatine near Hwy 61.
What about the best place to stay close to Muscatine Art Center?
One of the top choices for your stay is The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel, located a short 0.9 mi (1.4 km) from Muscatine Art Center, and this 4-star hotel offers a restaurant and an indoor pool. St. Mary Bed & Breakfast and Best Western Pearl City Inn are two other good choices within a few miles.
What are some accommodations with pools in Muscatine?
Best Western Muscatine / Pearl City Hotel: Features buffet, an indoor pool, and free self parking. AmericInn by Wyndham Muscatine and The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel are a couple of other choices with an onsite pool. View all hotels with pools in Muscatine.
What is the best hotel near Quad City International Airport (MLI)?
La Quinta Inn by Wyndham Moline Airport is a popular hotel, featuring free breakfast and an outdoor pool. It's located a short 0.4 mi (0.6 km) from Quad City Intl. Airport. Other choices close to the airport are Motel 6 Moline and Country Inn & Suites by Radisson, Moline Airport, IL.
What is staying in Muscatine like?
Visitors can enjoy all that Muscatine has to offer including the riverfront, baseball games, and theaters. Tourists can also enjoy the city's entertainment choices, monuments, and churches. In Muscatine, there are 16 hotels and other accommodations to choose from. Find out more about Muscatine.
What should I do while I'm visiting Muscatine?
The picturesque setting of Mississippi River and Cedar River exemplify the area's natural beauty. A couple of additional sights to add to your agenda are Wildcat Den State Park and Pine Creek Grist Mill. Check out what more to see and do in Expedia's Muscatine guide.
What's the weather like in Muscatine?
The hottest months are usually July and August with an average temp of 72°F, while the coldest months are January and February with an average of 30°F. The snowiest months in Muscatine are January, November, February, and December, with each month seeing an average of 7 inches of snowfall.

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