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Our top choices for Mayo Clinic hotels

Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
Mayo Clinic
8.2 out of 10, Very Good, (1,073 reviews)
"Spotless room, wonderful amenities, a MOST comfortable bed,polite staff. Will definitely stay here again. "
United States
Cathleen
The price is ¥26,003
¥29,635 total
includes taxes & fees
Mar 3 - Mar 4
Sonesta Select Scottsdale at Mayo Clinic Campus

Candlewood Suites Mesa Phoenix East by IHG

Candlewood Suites Mesa Phoenix East by IHG
2.5 star property
27.8 km from Mayo Clinic
9.2 out of 10, Wonderful, (85 reviews)
"The room was clean and great to have a full kitchen. Enjoyed our stay"
United States
Margo
The price is ¥21,514
¥24,583 total
includes taxes & fees
Feb 2 - Feb 3
Candlewood Suites Mesa Phoenix East by IHG

Wekopa Casino Resort

Wekopa Casino Resort
4.0 star property
10.1 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,001 reviews)
"The golf courses around and at the casino are great"
United States
Ryan
Wekopa Casino Resort

Fountain Park Hotel, BW Signature Collection

Fountain Park Hotel, BW Signature Collection
3.0 star property
7.2 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,007 reviews)
"Great Stay. Dana at front desk was extremely helpful."
United States
Bill
The price is ¥26,158
¥29,865 total
includes taxes & fees
Feb 8 - Feb 9
Fountain Park Hotel, BW Signature Collection

Home2 Suites by Hilton Mesa Longbow, AZ

Home2 Suites by Hilton Mesa Longbow, AZ
4.0 star property
14.7 km from Mayo Clinic
9.6 out of 10, Exceptional, (701 reviews)
"Hotel was great, would stay here again"
United States
Bryan
The price is ¥29,419
¥33,617 total
includes taxes & fees
Feb 8 - Feb 9
Home2 Suites by Hilton Mesa Longbow, AZ

SureStay Plus by Best Western Mesa Superstition Springs

SureStay Plus by Best Western Mesa Superstition Springs
2.5 star property
23.4 km from Mayo Clinic
8.4 out of 10, Very Good, (1,713 reviews)
"Clean rooms and proximity to shopping "
United States
Mae
The price is ¥17,800
¥20,340 total
includes taxes & fees
Feb 2 - Feb 3
SureStay Plus by Best Western Mesa Superstition Springs

La Quinta Inn & Suites by Wyndham Mesa Superstition Springs

La Quinta Inn & Suites by Wyndham Mesa Superstition Springs
3.0 star property
24.1 km from Mayo Clinic
8.2 out of 10, Very Good, (1,812 reviews)
"Clean rooms and friendly staff. "
United States
Maria
The price is ¥19,502
¥22,285 total
includes taxes & fees
Feb 2 - Feb 3
La Quinta Inn & Suites by Wyndham Mesa Superstition Springs

Inn at Eagle Mountain

Inn at Eagle Mountain
3.5 star property
3 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,008 reviews)
"The view was incredible and the location was perfect for us."
United States
Chad
Inn at Eagle Mountain

Holiday Inn Express & Suites Phoenix East - Gilbert by IHG

Holiday Inn Express & Suites Phoenix East - Gilbert by IHG
2.5 star property
24 km from Mayo Clinic
9.4 out of 10, Exceptional, (1,001 reviews)
"Great stay"
United States
Gilbert
The price is ¥23,527
¥26,884 total
includes taxes & fees
Feb 8 - Feb 9
Holiday Inn Express & Suites Phoenix East - Gilbert by IHG

Staybridge Suites Phoenix East - Gilbert by IHG

Staybridge Suites Phoenix East - Gilbert by IHG
3.0 star property
24 km from Mayo Clinic
9.6 out of 10, Exceptional, (868 reviews)
"great breakfast, nice spacious room"
United States
Christopher
The price is ¥24,146
¥27,590 total
includes taxes & fees
Feb 8 - Feb 9
Staybridge Suites Phoenix East - Gilbert by IHG

Superior Suites Phoenix Mesa

Superior Suites Phoenix Mesa
2.0 star property
19.5 km from Mayo Clinic
7.0 out of 10, Good, (1,001 reviews)
"Parking was easy, room was clean. I felt safe staying there "
United States
Charles
The price is ¥12,226
¥14,590 total
includes taxes & fees
Feb 2 - Feb 3
Superior Suites Phoenix Mesa

Hampton Inn by Hilton Carefree

Hampton Inn by Hilton Carefree
2.5 star property
29.2 km from Mayo Clinic
9.4 out of 10, Exceptional, (636 reviews)
"Clean room, free breakfast, restaurants are in walking distance"
United States
Lisa
The price is ¥21,322
¥24,152 total
includes taxes & fees
Feb 24 - Feb 25
Hampton Inn by Hilton Carefree

The Azure Hotel

The Azure Hotel
2.5 star property
19.2 km from Mayo Clinic
8.8 out of 10, Excellent, (1,638 reviews)
"Rooms were clean, beds were comfy and the hotel was generally quiet. "
United States
Aaron
The price is ¥17,413
¥20,673 total
includes taxes & fees
Feb 2 - Feb 3
The Azure Hotel

Hilton Vacation Club Scottsdale Links Resort

Hilton Vacation Club Scottsdale Links Resort
3.5 star property
11.4 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,002 reviews)
"Staff was friendly, beautiful place to stay. "
United States
Ron
The price is ¥28,812
¥37,425 total
includes taxes & fees
Feb 9 - Feb 10
Hilton Vacation Club Scottsdale Links Resort

Talking Stick Resort

Talking Stick Resort
4.0 star property
9 km from Mayo Clinic
9.2 out of 10, Wonderful, (4,389 reviews)
"Amazing stay"
United States
Charonda
The price is ¥43,044
¥53,492 total
includes taxes & fees
Mar 1 - Mar 2
Talking Stick Resort

Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North
3.0 star property
8.8 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,003 reviews)
"Great hotel "
United States
Laura
The price is ¥28,088
¥32,013 total
includes taxes & fees
Feb 8 - Feb 9
Aiden by Best Western Scottsdale North

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
3.0 star property
Central Scottsdale, 9 km from Mayo Clinic
8.8 out of 10, Excellent, (1,864 reviews)
"Fantastic room, staff and breakfast!"
United States
Terry G
The price is ¥24,850
¥28,321 total
includes taxes & fees
Feb 9 - Feb 10
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

Days Inn & Suites by Wyndham Mesa Near Phoenix

Days Inn & Suites by Wyndham Mesa Near Phoenix
3.0 star property
23 km from Mayo Clinic
9.0 out of 10, Wonderful, (2,158 reviews)
"Everything was clean, very friendly and breakfast was great! "
Canada
Cathleen and Martin
The price is ¥17,631
¥20,148 total
includes taxes & fees
Feb 8 - Feb 9
Days Inn & Suites by Wyndham Mesa Near Phoenix

Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District
2.5 star property
9.7 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,784 reviews)
"Very polite staff, great breakfast, clean room! "
United States
Kathryn
The price is ¥26,970
¥30,752 total
includes taxes & fees
Feb 9 - Feb 10
Comfort Suites Scottsdale Talking Stick Entertainment District

Staybridge Suites Scottsdale - Talking Stick by IHG

Staybridge Suites Scottsdale - Talking Stick by IHG
3.0 star property
9.8 km from Mayo Clinic
9.4 out of 10, Exceptional, (983 reviews)
"Clean room , breakfast delicious, courteous staff. "
United States
David
The price is ¥42,410
¥48,356 total
includes taxes & fees
Feb 2 - Feb 3
Staybridge Suites Scottsdale - Talking Stick by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Mayo Clinic

Find the best Mayo Clinic areas and neighborhoods for the activities you enjoy most.

Downtown Phoenix

A true urban neighborhood, Downtown Phoenix boasts major sports venues like Chase Field and Footprint Center, as well as cultural attractions such as the Arizona Science Center and Phoenix Art Museum. Easily accessible via Valley Metro Light Rail, enjoy walkable streets, friendly cafes, and local businesses.

Old Town

Old Town is known for its popular shops, and you can see some sights in the area like Western Spirit: Scottsdale's Museum of the West and Scottsdale Fashion Square.

Camelback East

Adjacent to Paradise Valley and Scottsdale, Camelback East Village boasts two main cores and sits between Piestewa Peak and Camelback Mountain. Explore the vibrant 24th Street and Camelback Road or 44th Street and Van Buren Street areas.

North Phoenix

While you're in North Phoenix, take in top sights like Reach 11 Sports Complex and jump on the metro at 19th Avenue/ Dunlap Station to see more of the city.

Central Scottsdale

While visiting Central Scottsdale, you might make a stop by sights like Scottsdale Ranch Park and Starfire Golf Club at Scottsdale Country Club.

Top Mayo Clinic Hotel Reviews

Frequently asked questions

What is Mayo Clinic like?
Travelers will be sure to find plenty to entertain them in Scottsdale's Mayo Clinic neighborhood.
Where is the best place to stay in Mayo Clinic?
Based on Expedia customer reviews, Sonesta Select Scottsdale at Mayo Clinic Campus is the highest ranked property in Mayo Clinic. This hotel is a short 4-minute walk from Mayo Clinic Scottsdale, and it offers a restaurant and an outdoor pool.
How many hotels will I be able to find in the Mayo Clinic area?
With 14 Expedia hotels and other accommodations in Mayo Clinic to choose from, this is a good starting point for exploring the greater Scottsdale area.
If I need to cancel my hotel reservation in Mayo Clinic, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in Mayo Clinic.
Where can I learn more about changing or cancelling my trip to Mayo Clinic?
For more information about updating your trip to Mayo Clinic or cancelling it, go to https://www.expedia.com/service/.
What is there to do around this Scottsdale neighborhood?
A few places to visit in the area around Mayo Clinic include Eagle Mountain Golf Course, Golf Club at Eagle Mountain, and SunRidge Canyon Golf Club. Make a stop at Talking Stick Resort Casino and OdySea Aquarium while you're sightseeing around the area.

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