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Our top choices for Mayo Clinic hotels

Courtyard
Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
Mayo Clinic
8.2 out of 10, Very Good, (1,074 reviews)
"Beautiful room, couteous and experienced front desk staff. Easiest check in."
United States
April
The price is ￥20,684
￥23,575 total
includes taxes & fees
Jan 20 - Jan 21
Sonesta Select Scottsdale at Mayo Clinic Campus
Interior detail
University Inn Tempe

University Inn Tempe

University Inn Tempe
2.5 star property
23 km from Mayo Clinic
9.0 out of 10, Wonderful, (948 reviews)
"A very convenient place to stay if you are going to ASU events"
United States
brent
The price is ￥16,910
￥19,289 total
includes taxes & fees
Jan 13 - Jan 14
University Inn Tempe
Terrace/patio
Wekopa Casino Resort

Wekopa Casino Resort

Wekopa Casino Resort
4.0 star property
10.1 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,001 reviews)
"It was an amazing stay! "
United States
Whitney
Wekopa Casino Resort
Property amenity
Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North
3.0 star property
8.8 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,009 reviews)
"Great hotel "
United States
Laura
The price is ￥20,368
￥23,213 total
includes taxes & fees
Jan 13 - Jan 14
Aiden by Best Western Scottsdale North
Mountain view
Inn at Eagle Mountain

Inn at Eagle Mountain

Inn at Eagle Mountain
3.5 star property
3 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,007 reviews)
"Great place to stay. "
United States
Alexandra
The price is ￥30,801
￥35,165 total
includes taxes & fees
Jan 18 - Jan 19
Inn at Eagle Mountain
Terrace/patio
Hilton Garden Inn Scottsdale North/Perimeter Center

Hilton Garden Inn Scottsdale North/Perimeter Center

Hilton Garden Inn Scottsdale North/Perimeter Center
3.0 star property
11.8 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,006 reviews)
"Clean room, wonderful staff, great breakfast!"
United States
Michelle
The price is ￥34,827
￥39,692 total
includes taxes & fees
Jan 19 - Jan 20
Hilton Garden Inn Scottsdale North/Perimeter Center
Lobby
Fountain Park Hotel, BW Signature Collection

Fountain Park Hotel, BW Signature Collection

Fountain Park Hotel, BW Signature Collection
3.0 star property
7.2 km from Mayo Clinic
8.8 out of 10, Excellent, (1,004 reviews)
"Clean room, nice staff...Dana very helpful."
Canada
John
The price is ￥18,789
￥21,453 total
includes taxes & fees
Jan 13 - Jan 14
Fountain Park Hotel, BW Signature Collection
Water park
Great Wolf Lodge Arizona

Great Wolf Lodge Arizona

Great Wolf Lodge Arizona
4.0 star property
10.3 km from Mayo Clinic
9.0 out of 10, Wonderful, (918 reviews)
"Awesome resort hotel for kids"
Canada
Vanessa
The price is ￥25,436
￥29,765 total
includes taxes & fees
Feb 10 - Feb 11
Great Wolf Lodge Arizona
Lobby
Hotel Valley Ho

Hotel Valley Ho

Hotel Valley Ho
4.5 star property
Arts District, 16.7 km from Mayo Clinic
9.6 out of 10, Exceptional, (2,192 reviews)
"Great place to stay! "
United States
Stephanie
The price is ￥52,348
￥59,663 total
includes taxes & fees
Jan 18 - Jan 19
Hotel Valley Ho
Water park
Arizona Grand Resort & Spa

Arizona Grand Resort & Spa

Arizona Grand Resort & Spa
4.0 star property
28.6 km from Mayo Clinic
8.6 out of 10, Excellent, (2,323 reviews)
"Great stay! "
United States
Tyson
The price is ￥28,262
￥46,239 total
includes taxes & fees
Jan 25 - Jan 26
Arizona Grand Resort & Spa
Free daily continental breakfast
La Quinta Inn & Suites by Wyndham Phoenix Mesa West

La Quinta Inn & Suites by Wyndham Phoenix Mesa West

La Quinta Inn & Suites by Wyndham Phoenix Mesa West
3.0 star property
22.4 km from Mayo Clinic
7.6 out of 10, Good, (1,424 reviews)
"Clean room, nice staff, "
United States
Tammy
The price is ￥14,068
￥16,076 total
includes taxes & fees
Jan 13 - Jan 14
La Quinta Inn & Suites by Wyndham Phoenix Mesa West
Terrace/patio
Hyatt Place Tempe / Phoenix / University

Hyatt Place Tempe / Phoenix / University

Hyatt Place Tempe / Phoenix / University
3.0 star property
22.1 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,138 reviews)
"Everything was excellent: the service, the hotel’s location, and the breakfast!"
United States
Amaris Dinorah Coya
The price is ￥29,368
￥33,500 total
includes taxes & fees
Jan 19 - Jan 20
Hyatt Place Tempe / Phoenix / University
Outdoor pool
Motel 6 Old town Scottsdale/Fashion Square

Motel 6 Old town Scottsdale/Fashion Square

Motel 6 Old town Scottsdale/Fashion Square
2.0 star property
Fashion Square, 16 km from Mayo Clinic
7.8 out of 10, Good, (1,074 reviews)
"Great place to stay!"
United States
Jeffrey
The price is ￥10,943
￥12,473 total
includes taxes & fees
Jan 13 - Jan 14
Motel 6 Old town Scottsdale/Fashion Square
Lobby
Vīb Hotel by Best Western Phoenix - Tempe

Vīb Hotel by Best Western Phoenix - Tempe

Vīb Hotel by Best Western Phoenix - Tempe
3.0 star property
22.8 km from Mayo Clinic
9.0 out of 10, Wonderful, (733 reviews)
"We had a great stay! Great location and really nice rooms "
United States
Itai
The price is ￥23,486
￥26,789 total
includes taxes & fees
Jan 15 - Jan 16
Vīb Hotel by Best Western Phoenix - Tempe
Terrace/patio
Hyatt House Tempe/Phoenix/University

Hyatt House Tempe/Phoenix/University

Hyatt House Tempe/Phoenix/University
2.5 star property
22.1 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,003 reviews)
"Room was clean, Staff was awesome."
United States
keith
The price is ￥29,928
￥34,139 total
includes taxes & fees
Jan 19 - Jan 20
Hyatt House Tempe/Phoenix/University
Exterior detail
Revival Scottsdale Studios

Revival Scottsdale Studios

Revival Scottsdale Studios
2.5 star property
Paradise Valley Village, 12.8 km from Mayo Clinic
7.4 out of 10, Good, (1,137 reviews)
"Nice rooms"
United States
Benito
The price is ￥13,829
￥15,638 total
includes taxes & fees
Jan 13 - Jan 14
Revival Scottsdale Studios
Rooftop bar, alfresco dining, open select days
Omni Tempe Hotel at ASU

Omni Tempe Hotel at ASU

Omni Tempe Hotel at ASU
4.0 star property
22.8 km from Mayo Clinic
9.4 out of 10, Exceptional, (1,376 reviews)
" Location was great, very clean and pool area is fabulous."
United States
Niaomi
The price is ￥28,925
￥37,498 total
includes taxes & fees
Jan 22 - Jan 23
Omni Tempe Hotel at ASU
Sports facility
Tempe Mission Palms, a Destination by Hyatt Hotel

Tempe Mission Palms, a Destination by Hyatt Hotel

Tempe Mission Palms, a Destination by Hyatt Hotel
3.5 star property
22.4 km from Mayo Clinic
9.2 out of 10, Wonderful, (1,002 reviews)
"Great location! "
United States
Stacy
The price is ￥40,894
￥52,051 total
includes taxes & fees
Jan 13 - Jan 14
Tempe Mission Palms, a Destination by Hyatt Hotel
4 outdoor pools, pool umbrellas, sun loungers
Holiday Inn Club Vacations Scottsdale Resort by IHG

Holiday Inn Club Vacations Scottsdale Resort by IHG

Holiday Inn Club Vacations Scottsdale Resort by IHG
4.0 star property
13.3 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,010 reviews)
"Loved the entire property and amenities!"
United States
Jena
The price is ￥33,631
￥44,626 total
includes taxes & fees
Jan 13 - Jan 14
Holiday Inn Club Vacations Scottsdale Resort by IHG
Exterior
Sonesta Suites Scottsdale Gainey Ranch

Sonesta Suites Scottsdale Gainey Ranch

Sonesta Suites Scottsdale Gainey Ranch
3.5 star property
12.4 km from Mayo Clinic
9.0 out of 10, Wonderful, (1,006 reviews)
"Great location Very nice room Great breakfast and happy hour"
United States
Michael
The price is ￥25,105
￥34,012 total
includes taxes & fees
Jan 18 - Jan 19
Sonesta Suites Scottsdale Gainey Ranch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Mayo Clinic

Find the best Mayo Clinic areas and neighborhoods for the activities you enjoy most.
Downtown Phoenix which includes signage and night scenes

Downtown Phoenix

A true urban neighborhood, Downtown Phoenix boasts major sports venues like Chase Field and Footprint Center, as well as cultural attractions such as the Arizona Science Center and Phoenix Art Museum. Easily accessible via Valley Metro Light Rail, enjoy walkable streets, friendly cafes, and local businesses.

Old Town

Old Town

Old Town is known for its popular shops, and you can see some sights in the area like Western Spirit: Scottsdale's Museum of the West and Scottsdale Fashion Square.

Papago Park featuring desert views as well as a small group of people

Camelback East

Adjacent to Paradise Valley and Scottsdale, Camelback East Village boasts two main cores and sits between Piestewa Peak and Camelback Mountain. Explore the vibrant 24th Street and Camelback Road or 44th Street and Van Buren Street areas.

Visitors explore exhibits on musical instrument creation at the Musical Instrument Museum in Phoenix Arizona

North Phoenix

While you're in North Phoenix, take in top sights like Reach 11 Sports Complex and jump on the metro at 19th Avenue/ Dunlap Station to see more of the city.

East Mesa

While you're in East Mesa, take in top sights like Salt River Tubing and jump on the metro at Superstition Springs Transit Center to see more of the city.

Top Mayo Clinic Hotel Reviews

The Westin Tempe

The Westin Tempe

10/10 Excellent
"Excellent "
David 1-night trip
Posted 10 hours ago
The Westin Tempe

Frequently asked questions

What is Mayo Clinic like?
Travelers will be sure to find plenty to entertain them in Scottsdale's Mayo Clinic neighborhood.
Where is the best place to stay in Mayo Clinic?
Based on Expedia customer reviews, Sonesta Select Scottsdale at Mayo Clinic Campus is the highest ranked property in Mayo Clinic. This hotel is a short 4-minute walk from Mayo Clinic Scottsdale, and it offers a restaurant and an outdoor pool.
How many hotels will I be able to find in the Mayo Clinic area?
With 14 Expedia hotels and other accommodations in Mayo Clinic to choose from, this is a good starting point for exploring the greater Scottsdale area.
If I need to cancel my hotel reservation in Mayo Clinic, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in Mayo Clinic.
Where can I learn more about changing or cancelling my trip to Mayo Clinic?
For more information about updating your trip to Mayo Clinic or cancelling it, go to https://www.expedia.com/service/.
What is there to do around this Scottsdale neighborhood?
A few places to visit in the area around Mayo Clinic include Eagle Mountain Golf Course, Golf Club at Eagle Mountain, and SunRidge Canyon Golf Club. Make a stop at Talking Stick Resort Casino and OdySea Aquarium while you're sightseeing around the area.

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