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Our top choices for Mayo Clinic hotels

Courtyard
Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus
3.0 star property
Mayo Clinic
8.2 out of 10, Very Good, (1073)
"Beautiful room, couteous and experienced front desk staff. Easiest check in."
United States
April
The price is ￥20,528
￥23,396 total
includes taxes & fees
Jan 20 - Jan 21
Sonesta Select Scottsdale at Mayo Clinic Campus
Terrace/patio
Hyatt Place Tempe / Phoenix / University

Hyatt Place Tempe / Phoenix / University

Hyatt Place Tempe / Phoenix / University
3.0 star property
22.1 km from Mayo Clinic
9.2 out of 10, Wonderful, (1135)
"Everything was excellent: the service, the hotel’s location, and the breakfast!"
United States
Amaris Dinorah Coya
The price is ￥21,178
￥24,157 total
includes taxes & fees
Jan 11 - Jan 12
Hyatt Place Tempe / Phoenix / University
Water park
Arizona Grand Resort & Spa

Arizona Grand Resort & Spa

Arizona Grand Resort & Spa
4.0 star property
28.6 km from Mayo Clinic
8.6 out of 10, Excellent, (2321)
"Great stay! "
United States
Tyson
The price is ￥27,301
￥45,063 total
includes taxes & fees
Jan 25 - Jan 26
Arizona Grand Resort & Spa
Rooftop bar, alfresco dining, open daily
The Westin Tempe

The Westin Tempe

The Westin Tempe
4.0 star property
22.7 km from Mayo Clinic
9.4 out of 10, Exceptional, (1002)
"Great location "
United States
Darrell
The price is ￥19,901
￥28,186 total
includes taxes & fees
Jan 11 - Jan 12
The Westin Tempe
Lobby
Hotel Valley Ho

Hotel Valley Ho

Hotel Valley Ho
4.5 star property
Arts District, 16.7 km from Mayo Clinic
9.6 out of 10, Exceptional, (2182)
"Great place to stay! "
United States
Stephanie
The price is ￥44,510
￥50,728 total
includes taxes & fees
Jan 11 - Jan 12
Hotel Valley Ho
7 restaurants, breakfast, lunch, dinner served; seafood
Talking Stick Resort

Talking Stick Resort

Talking Stick Resort
4.0 star property
9 km from Mayo Clinic
9.2 out of 10, Wonderful, (4308)
"Excellent accommodations"
Canada
Ray
The price is ￥35,116
￥44,507 total
includes taxes & fees
Jan 11 - Jan 12
Talking Stick Resort
Rooftop bar, alfresco dining, open select days
Omni Tempe Hotel at ASU

Omni Tempe Hotel at ASU

Omni Tempe Hotel at ASU
4.0 star property
22.8 km from Mayo Clinic
9.4 out of 10, Exceptional, (1368)
" Location was great, very clean and pool area is fabulous."
United States
Niaomi
The price is ￥24,947
￥32,928 total
includes taxes & fees
Jan 11 - Jan 12
Omni Tempe Hotel at ASU
3 outdoor pools, a heated pool, cabanas (surcharge), pool umbrellas
Scottsdale Plaza Resort & Villas (soon to be Kimpton)

Scottsdale Plaza Resort & Villas (soon to be Kimpton)

Scottsdale Plaza Resort & Villas (soon to be Kimpton)
4.0 star property
13.5 km from Mayo Clinic
8.8 out of 10, Excellent, (2171)
"Nice resort with clean rooms! Food at restaurant was amazing! Will return for a visit! "
Canada
Mahtab
The price is ￥29,485
￥40,137 total
includes taxes & fees
Jan 10 - Jan 11
Scottsdale Plaza Resort & Villas (soon to be Kimpton)
Terrace/patio
Hyatt House Tempe/Phoenix/University

Hyatt House Tempe/Phoenix/University

Hyatt House Tempe/Phoenix/University
2.5 star property
22.1 km from Mayo Clinic
9.2 out of 10, Wonderful, (1001)
"Room was clean, Staff was awesome."
United States
keith
The price is ￥25,174
￥28,714 total
includes taxes & fees
Jan 11 - Jan 12
Hyatt House Tempe/Phoenix/University
Lobby
Embassy Suites by Hilton Phoenix Downtown North

Embassy Suites by Hilton Phoenix Downtown North

Embassy Suites by Hilton Phoenix Downtown North
3.5 star property
28.5 km from Mayo Clinic
9.2 out of 10, Wonderful, (1240)
"Great rooms fantastic staff quality breakfast"
United States
Mike
The price is ￥23,000
￥26,007 total
includes taxes & fees
Jan 11 - Jan 12
Embassy Suites by Hilton Phoenix Downtown North
Terrace/patio
Wekopa Casino Resort

Wekopa Casino Resort

Wekopa Casino Resort
4.0 star property
10.1 km from Mayo Clinic
9.2 out of 10, Wonderful, (1000)
"It was an amazing stay! "
United States
Whitney
Wekopa Casino Resort
Exterior
Hyatt Place Scottsdale/Old Town

Hyatt Place Scottsdale/Old Town

Hyatt Place Scottsdale/Old Town
3.0 star property
Brown and Stetson Business, 15.6 km from Mayo Clinic
8.6 out of 10, Excellent, (1374)
"Great Stay! "
Canada
Bahareh
The price is ￥21,781
￥24,824 total
includes taxes & fees
Jan 11 - Jan 12
Hyatt Place Scottsdale/Old Town
Lobby
Vīb Hotel by Best Western Phoenix - Tempe

Vīb Hotel by Best Western Phoenix - Tempe

Vīb Hotel by Best Western Phoenix - Tempe
3.0 star property
22.8 km from Mayo Clinic
9.0 out of 10, Wonderful, (730)
"We had a great stay! Great location and really nice rooms "
United States
Itai
The price is ￥20,514
￥23,401 total
includes taxes & fees
Jan 12 - Jan 13
Vīb Hotel by Best Western Phoenix - Tempe
Lunch, dinner served; Mexican cuisine, pool views
Rise Uptown Hotel

Rise Uptown Hotel

Rise Uptown Hotel
4.0 star property
27.9 km from Mayo Clinic
9.2 out of 10, Wonderful, (1125)
"Great staff, great rooms."
United States
Robert
The price is ￥25,294
￥34,800 total
includes taxes & fees
Jan 12 - Jan 13
Rise Uptown Hotel
Fireplace
Sonesta Select Tempe Downtown

Sonesta Select Tempe Downtown

Sonesta Select Tempe Downtown
3.0 star property
22.7 km from Mayo Clinic
8.4 out of 10, Very Good, (1002)
"Location, staff were very nice"
United States
Emma
The price is ￥24,915
￥28,420 total
includes taxes & fees
Jan 11 - Jan 12
Sonesta Select Tempe Downtown
Water park
Great Wolf Lodge Arizona

Great Wolf Lodge Arizona

Great Wolf Lodge Arizona
4.0 star property
10.3 km from Mayo Clinic
9.0 out of 10, Wonderful, (915)
"Awesome resort hotel for kids"
Canada
Vanessa
The price is ￥28,049
￥32,823 total
includes taxes & fees
Jan 11 - Jan 12
Great Wolf Lodge Arizona
Exterior
Holiday Inn Express & Suites Tempe by IHG

Holiday Inn Express & Suites Tempe by IHG

Holiday Inn Express & Suites Tempe by IHG
2.5 star property
28 km from Mayo Clinic
8.8 out of 10, Excellent, (1019)
"Clean room, quiet stay, breakfast is very good. The staff and front desk ladies are so nice and polite."
United States
Irma
The price is ￥16,454
￥18,769 total
includes taxes & fees
Jan 11 - Jan 12
Holiday Inn Express & Suites Tempe by IHG
Lobby lounge
The McCormick Scottsdale

The McCormick Scottsdale

The McCormick Scottsdale
3.5 star property
13 km from Mayo Clinic
8.4 out of 10, Very Good, (1293)
"Clean room, good view, friendly staff. "
United States
Aravinda
The price is ￥17,550
￥25,365 total
includes taxes & fees
Jan 11 - Jan 12
The McCormick Scottsdale
Exterior
HYATT house Scottsdale/Old Town

HYATT house Scottsdale/Old Town

HYATT house Scottsdale/Old Town
3.0 star property
Downtown Scottsdale, 15.5 km from Mayo Clinic
8.8 out of 10, Excellent, (1141)
"Great stay, clean rooms and in the heart of town."
United States
Edmond
The price is ￥21,178
￥24,137 total
includes taxes & fees
Jan 11 - Jan 12
HYATT house Scottsdale/Old Town
Property amenity
Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North
3.0 star property
8.8 km from Mayo Clinic
9.0 out of 10, Wonderful, (1003)
"Great hotel "
United States
Laura
The price is ￥18,514
￥21,102 total
includes taxes & fees
Jan 14 - Jan 15
Aiden by Best Western Scottsdale North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Mayo Clinic

Find the best Mayo Clinic areas and neighborhoods for the activities you enjoy most.
Downtown Phoenix which includes signage and night scenes

Downtown Phoenix

A true urban neighborhood, Downtown Phoenix boasts major sports venues like Chase Field and Footprint Center, as well as cultural attractions such as the Arizona Science Center and Phoenix Art Museum. Easily accessible via Valley Metro Light Rail, enjoy walkable streets, friendly cafes, and local businesses.

Old Town

Old Town

Old Town is known for its popular shops, and you can see some sights in the area like Western Spirit: Scottsdale's Museum of the West and Scottsdale Fashion Square.

Papago Park featuring desert views as well as a small group of people

Camelback East

Adjacent to Paradise Valley and Scottsdale, Camelback East Village boasts two main cores and sits between Piestewa Peak and Camelback Mountain. Explore the vibrant 24th Street and Camelback Road or 44th Street and Van Buren Street areas.

Visitors explore exhibits on musical instrument creation at the Musical Instrument Museum in Phoenix Arizona

North Phoenix

While you're in North Phoenix, take in top sights like Reach 11 Sports Complex and jump on the metro at 19th Avenue/ Dunlap Station to see more of the city.

East Mesa

While you're in East Mesa, take in top sights like Salt River Tubing and jump on the metro at Superstition Springs Transit Center to see more of the city.

Top Mayo Clinic Hotel Reviews

Omni Scottsdale Resort & Spa at Montelucia

Omni Scottsdale Resort & Spa at Montelucia

10/10 Excellent
"Everyone there was very friendly and helpful "
Enoch E. Hartman 6-night trip
Posted 1 day ago
Omni Scottsdale Resort & Spa at Montelucia

Frequently asked questions

What is Mayo Clinic like?
Travelers will be sure to find plenty to entertain them in Scottsdale's Mayo Clinic neighborhood.
Where is the best place to stay in Mayo Clinic?
Based on Expedia customer reviews, Sonesta Select Scottsdale at Mayo Clinic Campus is the highest ranked property in Mayo Clinic. This hotel is a short 4-minute walk from Mayo Clinic Scottsdale, and it offers a restaurant and an outdoor pool.
How many hotels will I be able to find in the Mayo Clinic area?
With 14 Expedia hotels and other accommodations in Mayo Clinic to choose from, this is a good starting point for exploring the greater Scottsdale area.
If I need to cancel my hotel reservation in Mayo Clinic, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in Mayo Clinic.
Where can I learn more about changing or cancelling my trip to Mayo Clinic?
For more information about updating your trip to Mayo Clinic or cancelling it, go to https://www.expedia.com/service/.
What is there to do around this Scottsdale neighborhood?
A few places to visit in the area around Mayo Clinic include Eagle Mountain Golf Course, Golf Club at Eagle Mountain, and SunRidge Canyon Golf Club. Make a stop at Talking Stick Resort Casino and OdySea Aquarium while you're sightseeing around the area.

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