Find hotels in Lower Keys, FL from ¥16,479

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Compare 818 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Lower Keys hotels

Parmer's Resort

2.5 star property
9.0 out of 10, Wonderful, (1001)
"Had a wonderful time place is very nice enjoyed ourselves "
The price is ¥15,845
¥22,655 total
includes taxes & fees
Sep 23 - Sep 24
Parmer's Resort

Old Wooden Bridge Resort and Marina

2.5 star property
8.6 out of 10, Excellent, (258)
"Really I have the best experience and soon I want to go again "
The price is ¥11,366
¥33,593 total
includes taxes & fees
Sep 24 - Sep 25
Old Wooden Bridge Resort and Marina

Sugar Loaf Lodge

2.5 star property
8.2 out of 10, Very Good, (1004)
"Nice family owned spot. "
The price is ¥14,647
¥16,479 total
includes taxes & fees
Sep 23 - Sep 24
Sugar Loaf Lodge

Barnacle Resort

3.0 star property
8.2 out of 10, Very Good, (40)
"Perfect place for a quiet getaway."
The price is ¥30,492
¥38,004 total
includes taxes & fees
Sep 23 - Sep 24
Barnacle Resort

Looe Key Reef Resort

2.5 star property
7.4 out of 10, Good, (1004)
"We only stayed one night but it was nice and we enjoyed ourselves."
The price is ¥27,497
¥30,934 total
includes taxes & fees
Oct 20 - Oct 21
Looe Key Reef Resort

Atlantic View Luxury Villa with Pool

3.5 star property
10.0 out of 10, Exceptional, (1)
"We were here for a night and it was great. A nice rustic feel on a big property, with good view. "
Atlantic View Luxury Villa with Pool

Little Torch Cottages

2.0 star property
9.2 out of 10, Wonderful, (9)
"Felt like home. We'd stay here again!"
Little Torch Cottages

Almond Tree Inn Hotel - Adults Only

3.5 star property
10.0 out of 10, Exceptional, (1014)
"Beautiful quaint property with outstanding staff. Loved our visit and would highly recommend "
The price is ¥27,496
¥30,934 total
includes taxes & fees
Sep 28 - Sep 29
Almond Tree Inn Hotel - Adults Only

Simonton Court Historic Inn & Cottages

2.5 star property
9.8 out of 10, Exceptional, (830)
"Great breakfast on site."
The price is ¥21,605
¥24,306 total
includes taxes & fees
Sep 29 - Sep 30
Simonton Court Historic Inn & Cottages

Orchid Key Inn - Adults Only

3.5 star property
9.8 out of 10, Exceptional, (1014)
"Our stay was incredible "
The price is ¥28,895
¥32,507 total
includes taxes & fees
Sep 23 - Sep 24
Orchid Key Inn - Adults Only

The Marquesa Hotel

3.5 star property
9.8 out of 10, Exceptional, (1011)
"Beautiful, clean property! Would definitely stay there again!"
The price is ¥25,004
¥35,621 total
includes taxes & fees
Sep 29 - Sep 30
The Marquesa Hotel

H2O Suites - Adults Only

3.5 star property
9.8 out of 10, Exceptional, (562)
"The place was stunning. Quite, relaxing Amazing "
The price is ¥38,319
¥49,766 total
includes taxes & fees
Sep 24 - Sep 25
H2O Suites - Adults Only

Key West Villas

3.5 star property
9.8 out of 10, Exceptional, (238)
"Best place to stay in Key West. Perfect location and hospitality was over the top. Best Happy Hour in town."
Key West Villas

Yacht Haven Marina

3.5 star property
9.8 out of 10, Exceptional, (209)
"We loved staying on the houseboat! "
Yacht Haven Marina

The Gardens Hotel

4.0 star property
9.8 out of 10, Exceptional, (1004)
"Great property and location!"
The price is ¥28,602
¥32,178 total
includes taxes & fees
Sep 23 - Sep 24
The Gardens Hotel

Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

3.5 star property
9.8 out of 10, Exceptional, (115)
"Staff (Olga, Zana, Tim) went out of their way to make sure that all of our stay was excellent "
Alexanders Guesthouse - Adult Exclusive, LGBTQ Friendly

Hyatt Vacation Club at Windward Pointe, Key West

3.5 star property
9.6 out of 10, Exceptional, (1024)
"Gorgeous resort! Very clean and conveniently located. "
The price is ¥28,547
¥38,774 total
includes taxes & fees
Oct 7 - Oct 8
Hyatt Vacation Club at Windward Pointe, Key West

Island City House Hotel

3.0 star property
9.6 out of 10, Exceptional, (1007)
"Great place i will stay again for sure "
The price is ¥22,006
¥24,757 total
includes taxes & fees
Sep 24 - Sep 25
Island City House Hotel

The Grand Guesthouse

2.5 star property
9.6 out of 10, Exceptional, (1001)
"Great place and a great value. Very clean & a comfortable bed."
The price is ¥15,336
¥20,953 total
includes taxes & fees
Sep 24 - Sep 25
The Grand Guesthouse

Santa Maria Suites

4.0 star property
9.6 out of 10, Exceptional, (1007)
"Extremely appealing, very nice accommodation. Proximity to restaurants excellent. "
The price is ¥36,403
¥47,612 total
includes taxes & fees
Sep 28 - Sep 29
Santa Maria Suites
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Lower Keys attractions

Calusa Beach
Bahia Honda State Park, Beach at the Campground, view to the new Bridge.
If you like to get a spot here for your RV, you have to book up to 8 months in advance.

Calusa Beach

Why not spend a lazy afternoon at Calusa Beach during your trip to Big Pine Key? While you're in the area, wander around the natural setting.

Big Pine Key Flea Market

Big Pine Key Flea Market

You can find the perfect gifts to bring home at Big Pine Key Flea Market during your stay in Big Pine Key. Stroll along the marina or discover the sunrises in this relaxing area.

Coupon Bight Aquatic Preserve

Coupon Bight Aquatic Preserve

Commune with nature and explore the great outdoors at Coupon Bight Aquatic Preserve during your travels in Big Pine Key. While in this relaxing area, you can enjoy the restaurants.

Learn more about Lower Keys

Explore the relaxing area of Lower Keys—parks, boating, and sights from Florida Keys Beaches to Sugarloaf Beach.

Big Pine Key featuring a river or creek, a bay or harbor and general coastal views

Top Lower Keys Hotel Reviews

More cheap stays in Lower Keys

More cheap stays in Lower Keys

Hotels in Lower Keys with star-rating

Hotels in Lower Keys with star-rating

Explore a world of travel with Expedia

Explore a world of travel with Expedia