What's it like in Greater South Side?

Travelers are sure to enjoy a stay in Des Moines's Greater South Side neighborhood. Consider a visit to Gray’s Lake Park as part of your Greater South Side travel plans.

What's a favorite place to stay in Greater South Side?

Based on our traveler data, Days Inn & Suites by Wyndham Des Moines Airport is one of the top choices for your stay in Greater South Side. This hotel offers free breakfast and an indoor pool. Other good options for your stay in the neighborhood include Hampton Inn Des Moines-Airport and AmericInn by Wyndham Des Moines Airport .

How many hotels will I be able to find in Greater South Side?

With 17 Expedia hotels and other accommodations in Greater South Side to choose from, this is a good starting point for exploring the greater Des Moines area.

If I need to cancel my hotel reservation in Greater South Side, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Add your dates and click on "Search", then use the "fully refundable" filter to get top deals in Greater South Side.

Where can I learn more about changing or cancelling my trip to Greater South Side?

For more information about changing or cancelling your trip to Greater South Side, head over to our customer service page .

What is there to do around this Des Moines neighborhood?

Gray’s Lake Park is an attraction you might want to check out while you're in Greater South Side. While you're out sightseeing, Air Lanes Bowling Center and Lauridsen Amphitheater are a couple of additional sights to visit in Des Moines.

Top Greater South Side Hotels

A nighttime pedestrian bridge with illuminated railings and a rainbow-colored light projection on the floor.

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Our top choices for Greater South Side hotels

A spacious hotel lobby with a central bar, seating area, and a ceiling fan.

1. Hampton Inn Des Moines-Airport

Greater South Side

Jayson

￥16,730 total

includes taxes & fees

Oct 24 - Oct 25

A hotel room with a large bed, a nightstand, a wall-mounted TV, and a window with curtains.

2. Days Inn & Suites by Wyndham Des Moines Airport

Greater South Side

Amanda

￥11,576 total

includes taxes & fees

Nov 1 - Nov 2

A reception desk with a sign reading "AmericInn" and a clock on the wall.

3. AmericInn by Wyndham Des Moines Airport

Greater South Side

Alan

￥11,275 total

includes taxes & fees

Oct 25 - Oct 26

4. Quality Inn & Suites Des Moines Airport

Greater South Side

Barbara

￥11,357 total

includes taxes & fees

Nov 8 - Nov 9

A spacious indoor area with multiple levels, featuring a central open space with tables and chairs, surrounded by balconies and a large, colorful ceiling structure.

5. Holiday Inn Des Moines-Airport/Conf Center by IHG

Greater South Side

Reginald

￥19,504 total

includes taxes & fees

Oct 15 - Oct 16

A luxurious living room with a stone fireplace, a large mirror, and two blue armchairs.

6. Des Lux Hotel

Court District, 3.9 km from Greater South Side

Heidi

￥30,083 total

includes taxes & fees

Oct 13 - Oct 14

A spacious lobby with high ceilings, large windows, and a chandelier.

7. Hotel Fort Des Moines, Curio Collection by Hilton

Western Gateway, 3.7 km from Greater South Side

Kelsey

￥22,390 total

includes taxes & fees

Nov 8 - Nov 9

A spacious lobby with a bar area, seating arrangements, and a high ceiling with recessed lighting.

8. Des Moines Marriott Downtown

Downtown Des Moines, 4.1 km from Greater South Side

Nancy

￥23,937 total

includes taxes & fees

Oct 25 - Oct 26

A Holiday Inn Express building with a brick facade, multiple windows, and a covered entrance.

9. Holiday Inn Express & Suites Des Moines Downtown by IHG

Downtown Des Moines, 3.2 km from Greater South Side

Joe

￥18,262 total

includes taxes & fees

Nov 8 - Nov 9

A modern kitchen with dark cabinets, stainless steel appliances, and a tiled backsplash.

10. Staybridge Suites Des Moines Downtown by IHG

Historic East Village, 4.5 km from Greater South Side

Emily

￥20,213 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor seating area with a circular fire pit, wicker furniture, and string lights.

11. Residence Inn Des Moines Downtown

Court District, 3.9 km from Greater South Side

Nicole

￥21,688 total

includes taxes & fees

Nov 2 - Nov 3

A modern hotel lobby with a staircase, seating area, and a reception desk.

12. Hilton Des Moines Downtown

Downtown Des Moines, 4.5 km from Greater South Side

Sweta

￥25,309 total

includes taxes & fees

Nov 10 - Nov 11

A hotel facade with a prominent sign reading "SAVERY HOTEL" and "Renaissance Hotel."

13. Renaissance Des Moines Savery Hotel

Downtown Des Moines, 4.2 km from Greater South Side

Jayson

￥25,470 total

includes taxes & fees

Nov 1 - Nov 2

A spacious hotel lobby with a blue sofa, a grey armchair, and a flat-screen TV mounted on a textured wall.

14. Comfort Inn & Suites Event Center

Downtown Des Moines, 4.9 km from Greater South Side

Mario

￥16,427 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor patio area with tables and chairs, a fire pit, and string lights.

15. Fairfield Inn & Suites by Marriott Des Moines Downtown

Downtown Des Moines, 4.8 km from Greater South Side

Charles

￥17,007 total

includes taxes & fees

Nov 8 - Nov 9

A modern bar with wooden shelves and a long counter.

16. Surety Hotel, Autograph Collection

Court District, 3.8 km from Greater South Side

Brett

￥29,965 total

includes taxes & fees

Oct 25 - Oct 26

17. Embassy Suites Hotel Des Moines Downtown

Historic East Village, 4.4 km from Greater South Side

Candy

￥23,117 total

includes taxes & fees

Oct 18 - Oct 19

A modern dining area with a large island table, multiple chairs, and a chandelier.

18. Hampton Inn & Suites Des Moines Downtown

Court District, 3.9 km from Greater South Side

David A

￥18,755 total

includes taxes & fees

Oct 25 - Oct 26

A multi-story hotel with a classic brick facade, large windows, and a prominent Liberty Building sign.

19. Hyatt Place Des Moines/Downtown

Downtown Des Moines, 4.1 km from Greater South Side

Felicia

￥19,504 total

includes taxes & fees

Oct 25 - Oct 26

An outdoor seating area with yellow chairs and a colorful sofa, a fire pit, and a wooden ceiling with hanging lights.

20. Home2 Suites by Hilton Des Moines at Drake University

Drake, 5.6 km from Greater South Side

Cassandra

￥17,181 total

includes taxes & fees

Nov 10 - Nov 11

View all properties

Compare popular hotels in Greater South Side

Property	Star rating	Guest rating
Hampton Inn Des Moines-Airport	2.5 star property	8.8 Excellent 1,005 reviews	View
Days Inn & Suites by Wyndham Des Moines Airport	2.0 star property	8.6 Excellent 1,820 reviews	View
Holiday Inn Des Moines-Airport/Conf Center by IHG	3.0 star property	8.4 Very good 728 reviews	View
AmericInn by Wyndham Des Moines Airport	3.0 star property	8.0 Very good 1,001 reviews	View
Quality Inn & Suites Des Moines Airport	2.5 star property	7.6 Good 1,000 reviews	View

Where to stay in Greater South Side

Find the best Greater South Side areas and neighborhoods for the activities you enjoy most. Learn more about Greater South Side

The entrance to the Greater Des Moines Botanical Garden with a large dome structure in the background.

Downtown Des Moines

Downtown Des Moines boasts corporate campuses, fine dining, and unique retail destinations. Explore the Pappajohn Sculpture Park, and enjoy easy access to DART transit and skywalk connections.

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Historic East Village

Directly east of Downtown Des Moines, this nationally recognized historic district boasts the Iowa State Capitol complex, State of Iowa Historical Museum, and Des Moines Botanical Gardens. Explore eateries, boutique shops, and loft-style housing in its charming structures.

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A city skyline at night with illuminated buildings and a prominent tower.

Court District

Court District is known for its ample dining options, and you can make a stop by Science Center of Iowa and Principal Park while in the area.

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The exterior and interior of Mars Cafe, featuring a brick facade, large windows, and a red interior with hanging lights and artwork.

Drake

If you're spending some time in Drake, Knapp Center and Des Moines Community Playhouse are top sights worth seeing.

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A city skyline at dusk with illuminated buildings, a bridge, and a river.

Beaverdale

If you're looking for some top things to see and do in Beaverdale and surrounding area, you can visit Merle Hay Mall and Knapp Center.

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Top Greater South Side Hotel Reviews

Des Lux Hotel

10/10 Excellent

"Decor and bar were great- don’t forget your swimsuit - nice hot tub!"

Holiday Inn Des Moines-Airport/Conf Center by IHG

10/10 Excellent

"I love this hotel! It was excellent, as always. Also, we paid a small fee to leave our car at the hotel during the trip. The wonderful gentlemen who drives the shuttle bus dropped us off at the door to check our luggage, and picked us up almost immediately after we claimed our luggage. So quick and easy, and it cost less than using the airport parking, or the off-site parking, plus I know our car will be safe there. The people who run this hotel always go the extra mile. (The room even has a Keurig style coffee brewer. So nice!)"

Find hotels in Greater South Side, Des Moines

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Our top choices for Greater South Side hotels

1. Hampton Inn Des Moines-Airport

2. Days Inn & Suites by Wyndham Des Moines Airport

3. AmericInn by Wyndham Des Moines Airport

4. Quality Inn & Suites Des Moines Airport

5. Holiday Inn Des Moines-Airport/Conf Center by IHG

6. Des Lux Hotel

7. Hotel Fort Des Moines, Curio Collection by Hilton

8. Des Moines Marriott Downtown

9. Holiday Inn Express & Suites Des Moines Downtown by IHG

10. Staybridge Suites Des Moines Downtown by IHG

11. Residence Inn Des Moines Downtown

12. Hilton Des Moines Downtown

13. Renaissance Des Moines Savery Hotel

14. Comfort Inn & Suites Event Center

15. Fairfield Inn & Suites by Marriott Des Moines Downtown

16. Surety Hotel, Autograph Collection

17. Embassy Suites Hotel Des Moines Downtown

18. Hampton Inn & Suites Des Moines Downtown

19. Hyatt Place Des Moines/Downtown

20. Home2 Suites by Hilton Des Moines at Drake University

Compare popular hotels in Greater South Side

Where to stay in Greater South Side

Downtown Des Moines

Historic East Village

Court District

Drake

Beaverdale

Top Greater South Side Hotel Reviews

Des Lux Hotel

Frequently asked questions

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