An ancient amphitheater with stone seating and a small tower.

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Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

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Our top choices for Epipoli hotels

A bedroom with a bed, a desk, a chair, a wardrobe, and a large window with curtains.

1. B&B Kosmos

B&B Kosmos
3.0 star property
Epipoli
9.6 out of 10, Exceptional, (77 reviews)
"The menu was fresh but was also quite minimum. We were happy with it. We would happily recommend living with Salvo for visiting Syracuse. The location is well located in the city in a quiet neighbourhood, importantly it feels safe. "
United Kingdom
Kumar
The price is ￥14,289
￥16,290 total
includes taxes & fees
Oct 14 - Oct 15
B&B Kosmos
A swimming pool with lounge chairs and umbrellas, surrounded by buildings with arched windows and palm trees.

2. Hotel Relax

Hotel Relax
4.0 star property
Epipoli
8.2 out of 10, Very Good, (35 reviews)
"Good breakfast and nice pool. Pool rules were strange snd not matching the written ones. Easy parking"
United Kingdom
Fabrizio
The price is ￥21,376
￥24,368 total
includes taxes & fees
Oct 14 - Oct 15
Hotel Relax
A poolside setting with a person relaxing, a table with a drink and fruit, and a view of the pool and chairs in the background.

3. Hotel Parco delle Fontane

Hotel Parco delle Fontane
4.0 star property
Tiche, 1.5 km from Epipoli
9.2 out of 10, Wonderful, (307 reviews)
"Great staff very clean great food beautiful pool we loved it ♥️"
United States
Tony
The price is ￥23,564
￥26,863 total
includes taxes & fees
Sep 26 - Sep 27
Hotel Parco delle Fontane
A hotel entrance with a name sign, a potted plant, and a staircase.

4. Hotel Panorama

Hotel Panorama
4.0 star property
Neapolis, 2 km from Epipoli
7.6 out of 10, Good, (157 reviews)
"The property is dated and the bathroom are extremely small"
United States
rosario
The price is ￥15,455
￥17,618 total
includes taxes & fees
Sep 27 - Sep 28
Hotel Panorama
An outdoor swimming pool with a wooden deck, surrounded by white umbrellas and lounge chairs.

5. Mercure Siracusa Prometeo

Mercure Siracusa Prometeo
4.0 star property
Neapolis, 2.7 km from Epipoli
9.0 out of 10, Wonderful, (504 reviews)
"Wow, what a fantastic hotel. Super location for the Archeological Park & Museum. Rooms and amenities were great, the pool and sundeck perfect for a drink. Staff were friendly and helpful, breakfast was spectacular, everything you could want for a Sicilian breakfast. Rooms were modern and comfortable definitely a value for the price. "
United States
John
The price is ￥16,832
￥20,970 total
includes taxes & fees
Oct 11 - Oct 12
Mercure Siracusa Prometeo
A modern bedroom with a bed, bedside tables, a chair, a small stool, and a window with curtains.

6. Prometeo Rooms

Prometeo Rooms
2.9 km from Epipoli
9.4 out of 10, Exceptional, (36 reviews)
"Good location"
Australia
Flynn
The price is ￥11,227
￥13,458 total
includes taxes & fees
Oct 10 - Oct 11
Prometeo Rooms
A table with two wine glasses and a decorative item, viewed through a window overlooking a parking area with cars and greenery.

7. Gymnasium

Gymnasium
3.0 star property
Santa Lucia, 3.5 km from Epipoli
8.8 out of 10, Excellent, (42 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is ￥8,818
￥10,053 total
includes taxes & fees
Oct 14 - Oct 15
Gymnasium
A coastal terrace with wicker furniture, striped umbrellas, and a rocky backdrop.

8. Grand Hotel Villa Politi

Grand Hotel Villa Politi
4.0 star property
Grottasanta, 3.6 km from Epipoli
8.6 out of 10, Excellent, (974 reviews)
"Nice stay if you have a car"
France
abdulrahman
The price is ￥25,293
￥28,834 total
includes taxes & fees
Sep 18 - Sep 19
Grand Hotel Villa Politi
A modern hotel room with a flat-screen TV mounted on a dark wall, a white desk with a remote control, a bed with a black and white patterned bedspread, and a window with curtains.

9. Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia, 3.8 km from Epipoli
9.0 out of 10, Wonderful, (286 reviews)
"A really nice room, the bed was extremely comfortable and the staff were very friendly."
United Kingdom
Michael
The price is ￥11,678
￥13,313 total
includes taxes & fees
Oct 5 - Oct 6
Nostos rooms & Apartments
An aerial view of a resort with multiple swimming pools, palm trees, and a clear view of the coastline.

10. Minareto

Minareto
5.0 star property
6.6 km from Epipoli
8.8 out of 10, Excellent, (277 reviews)
"Nice facilities"
United Kingdom
Lekhbiro
The price is ￥65,981
￥74,361 total
includes taxes & fees
Sep 21 - Sep 22
Minareto
A historic building with ornate balconies, a grand entrance, and flags of the European Union and Italy.

11. Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia, 3.8 km from Epipoli
8.6 out of 10, Excellent, (695 reviews)
"The staff was helpful, rooms are simple, pretty good location- close to Ortigia by foot. Breakfast is GREAT & the lemon granita in the main lobby as complimentary was amazing!"
Canada
Alessandro
The price is ￥18,588
￥21,190 total
includes taxes & fees
Sep 15 - Sep 16
Grande Albergo Alfeo
A balcony with a table set for two, a chair, and a view of a building with multiple windows and balconies.

12. B&B Nike

B&B Nike
Santa Lucia, 3.8 km from Epipoli
9.0 out of 10, Wonderful, (89 reviews)
"Great location and comfortable stay!"
United States
Rosa
The price is ￥12,806
￥14,598 total
includes taxes & fees
Oct 4 - Oct 5
B&B Nike
A modern bedroom with a bed, a desk, and a chair. There are framed pictures on the wall.

13. B&B Spigolehouse

B&B Spigolehouse
3 km from Epipoli
8.2 out of 10, Very Good, (36 reviews)
"Amazing property, all attractions are very close"
United States
DAVID
The price is ￥15,890
￥18,115 total
includes taxes & fees
Sep 21 - Sep 22
B&B Spigolehouse
A balcony with a view of the sea, featuring a metal railing and potted plants.

14. Domus Mariae Albergo

Domus Mariae Albergo
3.0 star property
Ortigia, 4.7 km from Epipoli
9.2 out of 10, Wonderful, (387 reviews)
"Perfect staff perfect location hotel very clean"
United States
Marino
The price is ￥17,650
￥20,121 total
includes taxes & fees
Sep 15 - Sep 16
Domus Mariae Albergo
A hotel room with a large bed, a window with a view of buildings, a bedside table with a lamp, and a mirror on the wall.

15. Hotel Como

Hotel Como
3.0 star property
3.2 km from Epipoli
7.8 out of 10, Good, (447 reviews)
"Location is just across train station."
United States
Yinan
The price is ￥9,339
￥10,647 total
includes taxes & fees
Oct 4 - Oct 5
Hotel Como
A historic building with a central entrance, multiple balconies, and a large potted plant in front.

16. Algila' Ortigia Charme Hotel

Algila' Ortigia Charme Hotel
4.0 star property
Ortigia, 4.6 km from Epipoli
9.6 out of 10, Exceptional, (1,004 reviews)
"Fantastic property, fab breakfast and lovely staff, what more could you want!"
United Kingdom
Rachael
The price is ￥52,045
￥59,032 total
includes taxes & fees
Sep 15 - Sep 16
Algila' Ortigia Charme Hotel
A balcony with potted plants and a metal railing.

17. Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia, 3.7 km from Epipoli
8.6 out of 10, Excellent, (386 reviews)
"Fantastic breakfast, great cakes and good coffee. The rooms were comfortable and the location is great for all the important places to be in Siracusa. It was quiet and peaceful and the staff were helpful and friendly."
United Kingdom
Richard
The price is ￥11,517
￥13,129 total
includes taxes & fees
Oct 8 - Oct 9
Piccolo Hotel Casa Mia
A bakery display with various baked goods and a sign indicating apple and jam cake.

18. UNA Hotels One Siracusa Wellness & SPA

UNA Hotels One Siracusa Wellness & SPA
4.0 star property
Grottasanta, 3.6 km from Epipoli
8.6 out of 10, Excellent, (551 reviews)
"It’s a really beautiful hotel. Great staff, great food, AC works, beautiful spa. It’s in central place but not in the midst of all the chaos at the same time!"
United States
Tanasha
The price is ￥22,128
￥25,227 total
includes taxes & fees
Oct 14 - Oct 15
UNA Hotels One Siracusa Wellness & SPA
A poolside breakfast setup with a newspaper, fruit bowl, juice, and coffee.

19. Albatros Hotel

Albatros Hotel
4.0 star property
5 km from Epipoli
8.6 out of 10, Excellent, (116 reviews)
"Great hotel, super clean, helpful team and lovely pool and gardens."
United Kingdom
lynda
The price is ￥14,622
￥16,668 total
includes taxes & fees
Oct 5 - Oct 6
Albatros Hotel
A balcony with a table set for tea, a book, and a view of a building and water.

20. Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia, 3.7 km from Epipoli
7.8 out of 10, Good, (124 reviews)
"Very friendly and helpful staff."
United States
David
The price is ￥14,479
￥16,507 total
includes taxes & fees
Oct 6 - Oct 7
Hotel Mediterraneo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Epipoli

Find the best Epipoli areas and neighborhoods for the activities you enjoy most.
A historic waterfront with a stone bridge, illuminated buildings, and a calm water body.

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Teatro dei Pupi and Cathedral of Syracuse while you're in town.

A modern building with a unique triangular roof and a central spire.
Photo by William Keller
Open Photo by William Keller

Santa Lucia

Santa Lucia is noteworthy for its historic sites, and you can make a stop at top attractions like Porto Piccolo and Ionian Sea.

Ancient ruins with a large amphitheater surrounded by trees.
Photo by William Keller
Open Photo by William Keller

Neapolis

While visiting Neapolis, you might make a stop by sights like Archaeological Park of Neapolis and Greek Theatre of Syracuse.

An ancient amphitheater with stone ruins and a grassy field.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

A natural rock arch over a body of water with people paddling in kayaks.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Top Epipoli Hotel Reviews

Mercure Siracusa Prometeo

Mercure Siracusa Prometeo

10/10 Excellent
"We loved our stay here in Syracuse. We could walk to several historical attractions and even better we could walk to Ortigia. Be sure to book a sunset cruise. It was so beautiful and a lot of fun. It's only a 5-10 minute walk to catch the bus to the airport. Another plus! We highly recommend this hotel."
Stephanie 2-night trip
Posted 10 hours ago
Mercure Siracusa Prometeo

Frequently asked questions

What is Epipoli like?
Travelers to the Epipoli neighborhood in Syracuse will be sure to enjoy their stay.
What's the best accommodation in Epipoli?
Based on our traveler data, Hotel Relax is one of the top choices for your stay in Epipoli. This hotel offers a full-service spa and a restaurant.
How many hotels will I be able to find in the Epipoli area?
When you want to find places to stay in Syracuse, start by booking one of Expedia's 7 hotels and other accommodations in Epipoli.
If I need to cancel my hotel reservation in Epipoli, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals in Epipoli.
Where can I learn more about changing or cancelling my trip to Epipoli?
To find more details about changing or cancelling your trip to Epipoli, head over to our customer service page.
What can I see and do in this Syracuse neighborhood?
A few places to visit in the area around Epipoli include Cantine Pupillo, Greek Theatre of Syracuse, and Latomia del Paradiso. Rope-makers' Cave and Ear of Dionysius are also worth a visit when you're out sightseeing in Syracuse.

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