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Find hotels in Santa Lucia, Syracuse from ¥11,738
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Discover 3,846 Santa Lucia hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Grande Albergo Alfeo
Grande Albergo Alfeo
8.6 out of 10, Excellent, (642)

Caportigia Boutique Hotel
Caportigia Boutique Hotel
9.4 out of 10, Exceptional, (248)
The price is ¥27,603
¥32,112 total
includes taxes & fees
Oct 16 - Oct 17

Hotel Palazzo Cavalieri
Hotel Palazzo Cavalieri
9.0 out of 10, Wonderful, (32)
The price is ¥36,499
¥41,609 total
includes taxes & fees
Oct 5 - Oct 6

Lakkios
Lakkios
9.0 out of 10, Wonderful, (56)

B&B Nike
B&B Nike
9.0 out of 10, Wonderful, (69)

Fortaleza Charme House
Fortaleza Charme House
10.0 out of 10, Exceptional, (22)
The price is ¥24,190
¥27,576 total
includes taxes & fees
Oct 13 - Oct 14
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Lucia
Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.

Ortigia
Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.
Grottasanta
Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.
Tiche
Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.
Acradina
You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.
Neapolis
While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.
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