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Find hotels in Santa Lucia, Syracuse from ￥11,738

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Discover 3,846 Santa Lucia hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Grande Albergo Alfeo
Aerial view

Grande Albergo Alfeo

4.0 star property
8.6 out of 10, Excellent, (642)
"The hotel is very central in the main town of Siracusa. Plenty of good restaurants on the doorstep and only ten minute walk from the station. Ortigia only a 15 minute walk away. The bathroom facilities and room decor are slightly old fashioned but all working fine. "
Grande Albergo Alfeo
Caportigia Boutique Hotel
Terrace/patio

Caportigia Boutique Hotel

5.0 star property
9.4 out of 10, Exceptional, (248)
"Great base for exploring Syracuse. "
The price is ￥27,603
￥32,112 total
includes taxes & fees
Oct 16 - Oct 17
Caportigia Boutique Hotel
Hotel Palazzo Cavalieri
Suite | Soundproofing, free WiFi

Hotel Palazzo Cavalieri

4.0 star property
9.0 out of 10, Wonderful, (32)
"Enjoyed our stay, nice comfortable room and bed. Very nice breakfast buffet. Within a quick 5 min walk to Ortigia Island, also walkable to train and bus station. Would stay here again."
The price is ￥36,499
￥41,609 total
includes taxes & fees
Oct 5 - Oct 6
Hotel Palazzo Cavalieri
Lakkios
Suite, Balcony, Sea View | 1 bedroom, minibar, in-room safe, desk

Lakkios

3.0 star property
9.0 out of 10, Wonderful, (56)
"Nice location to where dining options and sites to see are numerous "
Lakkios
B&B Nike
Double or Twin Room, Balcony, Ocean View | Premium bedding, minibar, desk, soundproofing

B&B Nike

9.0 out of 10, Wonderful, (69)
"This is an AMAZING AND EXCEPTIONAL property! Tucked away in a residential area with just a three minute walk to the bus stop. The hotel is beautifully furnished and modern. The rooms are spacious and inviting. This boutique hotel feels like a luxury five star hotel. I definitely want to come back to Cagliari, and when I do, rest assured I will be staying at Nemo. Also breakfast on the roof top is amazing! "
B&B Nike
Fortaleza Charme House
Superior Triple Room, Sea View | Memory foam beds, in-room safe, individually furnished, desk

Fortaleza Charme House

10.0 out of 10, Exceptional, (22)
"Lovely hotel, very friendly service, huge rooms. "
The price is ￥24,190
￥27,576 total
includes taxes & fees
Oct 13 - Oct 14
Fortaleza Charme House
San Nicola Rooms Siracusa
Exterior

San Nicola Rooms Siracusa

9.0 out of 10, Wonderful, (2)
"Não se espante com o prédio onde está localizado o hotel (fica no terceiro andar). Os quartos são novos e muito confortáveis. E ficar atento porque não há estacionamento grátis, mas sim pago na rua. "
The price is ￥14,964
￥17,059 total
includes taxes & fees
Oct 10 - Oct 11
San Nicola Rooms Siracusa
Siracusa Resort Musciara
Private beach, free beach cabanas, sun loungers, beach umbrellas

Siracusa Resort Musciara

3.0 star property
9.6 out of 10, Exceptional, (37)
"Very clean, lovely hotel with a wide variety of room choices. The dining area is on the water - very nice place to eat a meal. The beach is fantastic! It's an easy walk into old town Ortigia. Convenient parking lot next door."
The price is ￥61,979
￥69,926 total
includes taxes & fees
Oct 5 - Oct 6
Siracusa Resort Musciara
B&B Triskeles
Interior detail

B&B Triskeles

3.0 star property
8.2 out of 10, Very Good, (57)
"Excellent stay, close to everything and easy parking"
The price is ￥10,298
￥11,738 total
includes taxes & fees
Oct 1 - Oct 2
B&B Triskeles
Casa Miranda Boutique
Quadruple Room, 1 King Bed with Sofa bed, Sea View, Tower | Terrace/patio

Casa Miranda Boutique

The price is ￥32,556
￥37,113 total
includes taxes & fees
Oct 29 - Oct 30
Casa Miranda Boutique
Hotel Le Muse
Exterior

Hotel Le Muse

3.0 star property
7.4 out of 10, Good, (68)
"The room was great and the staff was exceptionally helpful"
The price is ￥17,825
￥20,321 total
includes taxes & fees
Oct 9 - Oct 10
Hotel Le Muse
Giuggiulena Villa
Property entrance

Giuggiulena Villa

3.0 star property
10.0 out of 10, Exceptional, (125)
"Fantastic stay. Made to feel very welcome and what a lovely relaxing place to stay. Evening meal was exceptional. "
The price is ￥27,326
￥31,152 total
includes taxes & fees
Oct 19 - Oct 20
Giuggiulena Villa
Nostos rooms & Apartments
Coffee/tea maker, electric kettle

Nostos rooms & Apartments

3.0 star property
9.0 out of 10, Wonderful, (267)
"The staff were friendly. The room was quiet and clean. There is no elevator."
The price is ￥11,998
￥13,676 total
includes taxes & fees
Oct 21 - Oct 22
Nostos rooms & Apartments
Re Dionisio Luxury Suites
Water view

Re Dionisio Luxury Suites

3.0 star property
8.8 out of 10, Excellent, (54)
"Wonderful property, excellent staff and the most amazing view from the apartment"
The price is ￥51,959
￥58,903 total
includes taxes & fees
Oct 18 - Oct 19
Re Dionisio Luxury Suites
Gymnasium
Full-size fridge, oven, stovetop, cookware/dishes/utensils

Gymnasium

3.0 star property
9.0 out of 10, Wonderful, (37)
"Great location, clean new comfortable room and kitt. "
Gymnasium
Hotel dei Coloniali
Exterior

Hotel dei Coloniali

3.0 star property
7.4 out of 10, Good, (164)
"Convenient location for Syracuse town, but in a scruffy area and the whole property is looking tired. Breakfast was adequate. The owner was charming and happy to help."
The price is ￥11,026
￥12,569 total
includes taxes & fees
Oct 12 - Oct 13
Hotel dei Coloniali
Piccolo Hotel Casa Mia
Terrace/patio

Piccolo Hotel Casa Mia

3.0 star property
8.6 out of 10, Excellent, (369)
"Nice quirky place to stay in Siracusa located conveniently for everything you need and very professional staff "
Piccolo Hotel Casa Mia
Hotel Mediterraneo
View from room

Hotel Mediterraneo

3.0 star property
7.8 out of 10, Good, (121)
"Nice clean room, pleasant staff, great location."
Hotel Mediterraneo
Populus
Terrace/patio

Populus

1.0 star property
7.8 out of 10, Good, (73)
"Just stay somewhere else, plain and simple."
The price is ￥11,677
￥15,054 total
includes taxes & fees
Oct 8 - Oct 9
Populus
Agorà
Triple Room, Housekeeping, City View | Desk, laptop workspace, free WiFi

Agorà

The price is ￥15,649
￥18,832 total
includes taxes & fees
Oct 7 - Oct 8
Agorà
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.
Temple of Apollo featuring a ruin and heritage elements

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Neapolis

While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.

Top Santa Lucia Hotel Reviews

Hotel Como

Hotel Como

10/10 Excellent
"Directly across from the train station and I didn’t hear anything. The staff were very nice and the breakfast was great. I wish that the bed was elevated about 8-10”. It was very comfortable but hard to get out of bed for an old man like myself! "
John 1-night trip
Posted 7 hours ago
Hotel Como

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What is Santa Lucia like?

Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.

Where is the best place to stay in Santa Lucia?

Based on Expedia customer reviews, Fortaleza Charme House is the highest ranked property in Santa Lucia. This inn is a short 6-minute walk from Lungomare di Ortigia, and it offers a beach bar and free WiFi. Other top choices in the neighborhood include Caportigia Boutique Hotel and Nostos rooms & Apartments.

How many hotels can I expect to find in Santa Lucia?

Expedia has 271 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.

If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.

Where can I learn more about changing or cancelling my trip to Santa Lucia?

For more details about changing or cancelling your trip to Santa Lucia, click here.

What are the top things to see and do in Santa Lucia?

Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.