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Check prices for these dates

Tonight
Apr 5 - Apr 6
Tomorrow
Apr 6 - Apr 7
Next weekend
Apr 10 - Apr 12
In two weeks
Apr 17 - Apr 19

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Our top choices for Santa Lucia hotels

Comfort Double Room | Soundproofing, free WiFi

Melody rooms

Melody rooms
Santa Lucia
The price is ￥6,779
￥7,727 total
includes taxes & fees
Apr 9 - Apr 10
Melody rooms
Rooftop terrace

Caportigia Boutique Hotel

Caportigia Boutique Hotel
5.0 star property
Santa Lucia
9.4 out of 10, Exceptional, (269 reviews)
"Excellent modern property, staff are all amazing. Walkable to everything."
Canada
Brian
The price is ￥30,308
￥35,178 total
includes taxes & fees
Apr 18 - Apr 19
Caportigia Boutique Hotel
Terrace/patio

Le Camere Luxsury Rooms

Le Camere Luxsury Rooms
Santa Lucia
The price is ￥7,570
￥12,824 total
includes taxes & fees
Apr 28 - Apr 29
Le Camere Luxsury Rooms
1 bedroom, down comforters, minibar, in-room safe

Re Dionisio Luxury Suites

Re Dionisio Luxury Suites
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (57 reviews)
"Spacious room, dated but comfortable."
United States
Kenneth
The price is ￥32,983
￥38,121 total
includes taxes & fees
Apr 5 - Apr 6
Re Dionisio Luxury Suites
Exclusive Room | In-room safe, soundproofing, iron/ironing board, free WiFi

Isonzo Suites

Isonzo Suites
Santa Lucia
8.8 out of 10, Excellent, (6 reviews)
"."
Italy
Gianluca
The price is ￥10,885
￥17,860 total
includes taxes & fees
Apr 6 - Apr 7
Isonzo Suites
Comfort Triple Room, Balcony, Ocean View | View from room

Hotel Mediterraneo

Hotel Mediterraneo
3.0 star property
Santa Lucia
7.8 out of 10, Good, (123 reviews)
"Very friendly and helpful staff."
United States
David
The price is ￥12,534
￥14,289 total
includes taxes & fees
Apr 12 - Apr 13
Hotel Mediterraneo
Porch

Piccolo Hotel Casa Mia

Piccolo Hotel Casa Mia
3.0 star property
Santa Lucia
8.6 out of 10, Excellent, (375 reviews)
"The staff is extremely nice and friendly and you feel welcome. "
Canada
Florentina
The price is ￥10,817
￥12,331 total
includes taxes & fees
Apr 20 - Apr 21
Piccolo Hotel Casa Mia
Premium bedding, down comforters, memory foam beds, in-room safe

Eos Sea View Apartment

Eos Sea View Apartment
Santa Lucia
The price is ￥23,138
￥27,291 total
includes taxes & fees
Apr 9 - Apr 10
Eos Sea View Apartment
Classic Room | View from room

Gymnasium

Gymnasium
3.0 star property
Santa Lucia
8.8 out of 10, Excellent, (40 reviews)
"Nice kitchen area, centrally located."
United States
Richard
The price is ￥10,217
￥11,646 total
includes taxes & fees
Apr 5 - Apr 6
Gymnasium
Coffee/tea maker, electric kettle

Nostos rooms & Apartments

Nostos rooms & Apartments
3.0 star property
Santa Lucia
9.0 out of 10, Wonderful, (276 reviews)
"Welcoming, room, staff and area around definitely stood out!"
Canada
Aina
The price is ￥11,562
￥13,180 total
includes taxes & fees
Apr 8 - Apr 9
Nostos rooms & Apartments
Double Room | Premium bedding, desk, cribs/infant beds, rollaway beds

B&B Siracusa

B&B Siracusa
Santa Lucia
9.0 out of 10, Wonderful, (59 reviews)
"Good location, very modern clean accommodation."
Canada
Malcolm
The price is ￥13,693
￥15,610 total
includes taxes & fees
Apr 5 - Apr 6
B&B Siracusa
Free daily buffet breakfast

San Nicola Rooms Siracusa

San Nicola Rooms Siracusa
Santa Lucia
9.2 out of 10, Wonderful, (5 reviews)
"Quarto bem decorado, um pouco apertado só tem lugar para uma mala. A reserva foi quarto de casal, mas nos colocaram em camas de solteiro, o problema era que o colchão escorregava. Eu reservei locais com elevador, muito antigo e tinha que subir com a mala por uns 10 degraus até o elevador.a equipe simpática e atenciosa, o café da manhã simples, mas de qualidade. Muito bonita a decoração dos espaços. A localização pelo app da expedia mostra outro endereço. Tivemos dificuldade de encontrar a...
Brazil
Paula
The price is ￥18,726
￥21,348 total
includes taxes & fees
Apr 5 - Apr 6
San Nicola Rooms Siracusa
Front of property

Grande Albergo Alfeo

Grande Albergo Alfeo
4.0 star property
Santa Lucia
8.6 out of 10, Excellent, (657 reviews)
"Good front desk staff, welcoming breakfast staff, clean room and good area for walking to attractions. "
Canada
Reita
The price is ￥18,056
￥20,585 total
includes taxes & fees
Apr 9 - Apr 10
Grande Albergo Alfeo
Lobby lounge

Regina Margherita

Regina Margherita
Santa Lucia
7.8 out of 10, Good, (16 reviews)
"The area is so close to the Ortigia Island where the beautiful cathedral and Doumo are. Lovely walk around the entire island and areas to go in the water If you like. Many dining options and shopping too. Wonderful area!"
United States
Laura
The price is ￥10,503
￥11,972 total
includes taxes & fees
Apr 29 - Apr 30
Regina Margherita
View from room

Calafatari B&B

Calafatari B&B
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (11 reviews)
"We had a lovely stay. Anna was very welcoming. We had a lovely large clean room and a nice modern bathroom. She went all out for breakfast. "
United States
Carl and Lina
The price is ￥26,482
￥30,189 total
includes taxes & fees
Apr 7 - Apr 8
Calafatari B&B
Free WiFi

B&B L'INFIORESCENZA

B&B L'INFIORESCENZA
Santa Lucia
The price is ￥5,341
￥8,185 total
includes taxes & fees
Apr 7 - Apr 8
B&B L'INFIORESCENZA
Triple Room, Balcony | Balcony

B&B Nike

B&B Nike
Santa Lucia
8.8 out of 10, Excellent, (75 reviews)
"Clean, good location. "
United States
Salvatore
The price is ￥13,217
￥15,067 total
includes taxes & fees
Apr 18 - Apr 19
B&B Nike
Apartment, Balcony, Partial Sea View | Interior

Eos Serenity Suites

Eos Serenity Suites
Santa Lucia
The price is ￥17,387
￥19,821 total
includes taxes & fees
Apr 8 - Apr 9
Eos Serenity Suites
Breakfast area

Giuggiulena Villa

Giuggiulena Villa
3.0 star property
Santa Lucia
10.0 out of 10, Exceptional, (126 reviews)
"Fantastic stay. Made to feel very welcome and what a lovely relaxing place to stay. Evening meal was exceptional. "
United States
Paul
The price is ￥34,608
￥39,454 total
includes taxes & fees
Apr 13 - Apr 14
Giuggiulena Villa
Exterior

Populus

Populus
1.0 star property
Santa Lucia
7.8 out of 10, Good, (74 reviews)
"Just stay somewhere else, plain and simple."
United States
Thomas
The price is ￥9,242
￥10,537 total
includes taxes & fees
Apr 7 - Apr 8
Populus
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Santa Lucia

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Breakfast area
Giuggiulena Villa
3.0 star property
10.0
Exceptional
126 reviews
View
Rooftop terrace
Caportigia Boutique Hotel
5.0 star property
9.4
Exceptional
269 reviews
View
Coffee/tea maker, electric kettle
Nostos rooms & Apartments
3.0 star property
9.0
Wonderful
276 reviews
View
Suite, Balcony, Sea View | Minibar, in-room safe, desk, soundproofing
Lakkios
3.0 star property
9.0
Wonderful
64 reviews
View
Classic Room | View from room
Gymnasium
3.0 star property
8.8
Excellent
40 reviews
View

Where to stay in Santa Lucia

Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most.

Ortigia

Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.

Grottasanta

Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.

Photo by William Keller
Open Photo by William Keller

Neapolis

While visiting Neapolis, you might make a stop by sights like Archaeological Park of Neapolis and Greek Theatre of Syracuse.

Syracuse, panoramic phot of the Roman Amphitheatre at Syracuse (Siracusa), UNESCO World Heritage Site, Sicily, Italy, Europe

Tiche

Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.

Acradina

You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.

Top Santa Lucia Hotel Reviews

Fortaleza Charme House

Fortaleza Charme House

10/10 Excellent
"The location is perfect. The staff is very helpful and friendly. We enjoyed the wonderful tall rooms and the comfort of being close to shops, restaurants and the interesting archeological sites and museums. We will certainly recommend this location and will return in the future."
Peter 4-night trip
Posted 6 hours ago
Fortaleza Charme House

Frequently asked questions

What is Santa Lucia like?
Santa Lucia is a neighborhood that people enjoy for its interesting historical sites. Are you looking for Santa Lucia travel tips? Be sure to check out Porto Piccolo and Ionian Sea while you're in the neighborhood.
Where is the best place to stay in Santa Lucia?
Based on Expedia customer reviews, Nostos rooms & Apartments is the highest ranked property in Santa Lucia. This B&B offers free WiFi and valet parking. Other top choices in the neighborhood include La casa di Aneupe and Lakkios.
How many hotels can I expect to find in Santa Lucia?
Expedia has 303 hotels and other accommodations in Santa Lucia to choose from, making this an ideal home base for exploring the greater Syracuse area.
If I need to cancel my hotel reservation in Santa Lucia, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then use the filter option "fully refundable" to get the best options available in Santa Lucia.
Where can I learn more about changing or cancelling my trip to Santa Lucia?
For more details about changing or cancelling your trip to Santa Lucia, click here.
What are the top things to see and do in Santa Lucia?
Landmarks in Santa Lucia that you won't want to miss include Syracuse Forum Ruins and Santa Lucia Bridge. Porto Piccolo and Ionian Sea are some other stops to visit in the neighborhood. A few places to visit in the area around Santa Lucia include Piazza Santa Lucia, Santa Lucia al Sepolcro Basilica, and Madonna delle Lacrime. When you're sightseeing in Syracuse, Papyrus Museum and Museo Archeologico Regionale Paolo Orsi are also worth a stop.

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