Santa Lucia Vacations
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ￥109,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Where to stay in Santa Lucia
Find the best Santa Lucia areas and neighborhoods for the activities you enjoy most. Learn more about Santa Lucia
Ortigia
4 out of top 10 points of interest in this area
Travelers come to Ortigia for its seaside views, and you can see top attractions like Cathedral of Syracuse and Piazza del Duomo while you're in town.
Grottasanta
1 out of top 10 points of interest in this area
Grottasanta is noteworthy for its historic sites, and you can make a stop at top attractions like Pista Ciclabile Siracusa and Ionian Sea.
Neapolis
3 out of top 10 points of interest in this area
While visiting Neapolis, you might make a stop by sights like Roman Amphitheatre of Syracuse and Archaeological Park of Neapolis.
Tiche
Gardens and restaurants are notable features of Tiche. You might consider a stop by Ionian Sea while you're exploring the neighborhood.
Acradina
You'll enjoy the churches and seaside views in Acradina. You might want to make time for a stop at Ionian Sea or Capuchin Quarry.
Santa Lucia Hotel Deals
Grande Albergo Alfeo
Via Nino Bixio 5 Syracuse SR
Fully refundableReserve now, pay when you stay
￥12,235
￥13,948 total
Nov 15 - Nov 16
includes taxes & fees
8.6/10 Excellent! (709 reviews)
"Very noisy on the weekends. Restaurants and bars across the road were lively until 4:00 am. Hotels is tired looking."
Reviewed on Oct 20, 2026
Hotel Palazzo Cavalieri
42 Via Malta Syracuse SR
Fully refundableReserve now, pay when you stay
￥10,717
￥12,217 total
Nov 15 - Nov 16
includes taxes & fees
9/10 Wonderful! (50 reviews)
"Very responsive staff that helped me organize transportation to and from the airport, accommodation for my baby, and a surprise welcome for my wife’s birthday. Amazing location just outside Ortigia, I honestly preferred staying there than on the island. Highly recommended."
Reviewed on Oct 1, 2026
Caportigia Boutique Hotel
Viale Montedoro 76 Syracuse SR
Fully refundableReserve now, pay when you stay
￥22,054
￥26,036 total
Nov 21 - Nov 22
includes taxes & fees
9.2/10 Wonderful! (300 reviews)
"Overall the hotel was very nice and in perfect location. We would definitely stay again. Some items they could improve. The reading lights above bed did not work and there was no other source of light except the huge lights for the entire room. The shower floor was super super super slippery. Both ..."
Reviewed on Sep 28, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
How much does a Santa Lucia vacation package cost?
Our Santa Lucia packages, which start from just , are the perfect way to save loads of cash. All you have to do is choose your preferred flights, hotels and rental cars to create your ideal escape.
How do I get a cheap travel package to Santa Lucia?
Combine your hotels and flights, throw in extras such as a rental car or activities, and save with a Santa Lucia vacation package. You won't just score big discounts on your escape — you'll have lots of choice at your fingertips too. When you book with Expedia, you can choose from more than 550 airlines and 1,000,000 hotels all over the world. Your affordable vacation begins right here, right now!
Where should I stay in Santa Lucia?
Take the hassle out of sightseeing by staying in a hotel right around the corner from Santa Lucia's iconic attractions. Cathedral of Syracuse and Temple of Apollo are two visitor favorites.
What are the top hotels in Santa Lucia?
If this will be your first time in Santa Lucia, book a room at Hotel Cavalieri or Paolanna Luxury Rooms. Both hotels offer friendly service and are popular options with many travelers.
How far in advance should I book my Santa Lucia vacation?
Smart travelers will likely want to reserve their seats early. You can normally compare international fares on Expedia up to 12 months before your flight. If you're purchasing tickets last minute, don't stress. Budget prices occasionally appear in the last weeks prior to departure.
What does an Expedia Santa Lucia travel package include?
Packages include hotels, flights and rental cars, but you can mix and match them to create your ideal Santa Lucia vacation. You can also add on some activities and experiences once you've made your booking. You're in charge! When you bundle your bookings with Expedia, you'll score discounts you won't find anywhere else.
What should I know before booking a Santa Lucia travel package?
You'll land impressive savings when you bundle your hotels, flights and rental cars into a package. Plus, booking everything in one place will make your trip planning easier. So why waste money or time? Whether you're putting together a ritzy romantic getaway or a budget family adventure, browse our package deals today.
Can I choose my airline with a Santa Lucia Expedia vacation package?
You can, and with more than 550 airlines to pick from globally, you have plenty of choice. Search the available options and find out which airline best fits your needs and budget.
If I'm not able to travel, can I cancel my Santa Lucia vacation package?
Yes, you can. We realize life doesn't always go to plan, so we're here to help if you have to make changes to your Santa Lucia vacation package. It may be possible to cancel or amend your itinerary at no cost if you've booked in the last 24 hours. Your airline, hotel or car rental company may charge you a fee if your booking was made more than 24 hours ago. Visit our Customer Service Portal for further information. Also, check your itinerary for the nitty-gritty on change fees.
Stay near popular Santa Lucia attractions
Porto Piccolo
8.8/10 (189 reviews)
Explore the waterfront in Syracuse with a trip to Porto Piccolo. Wander the seaside in this culturally rich area.
Santa Lucia Bridge
8.8/10 (13 reviews)
Santa Lucia Bridge is just one of the places to see in Syracuse, so why not enjoy the other things to explore during your travels? Discover the museums and monuments in this walkable area.
Syracuse Forum Ruins
You can learn about the history of Syracuse with a trip to Syracuse Forum Ruins. Wander the beautiful beaches and seaside in this culturally rich area.
Madonna delle Lacrime
8.8/10 (16 reviews)
You can study the exhibits at Madonna delle Lacrime, a museum with a story of its own, during your trip to Syracuse. Wander the seaside in this culturally rich area.
Santa Lucia al Sepolcro Basilica
Find out about the history of Syracuse when you take a trip to Santa Lucia al Sepolcro Basilica. Wander the seaside in this culturally rich area.
Papyrus Museum
8.0/10 (1 review)
You can browse the exhibits at Papyrus Museum, a museum with a storied past, during your travels to Syracuse. Wander the seaside in this culturally rich area.
Piazza Santa Lucia
8.0/10 (1 review)
You can find out about the history of Syracuse with a trip to Piazza Santa Lucia. Wander the beautiful beaches and seaside in this culturally rich area.
Things to do
Syracuse: Ortigia Island and Sea Caves Boat Tour
￥3,604
per adult
Syracuse: Pillirina, Ortigia, and Sea Caves Tour by Boat
￥7,207
per adult
Syracuse: Ortigia and Sea Caves Excursion by Boat
￥3,604
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.