The Best Hotels Closest to Duke Regional Hospital in Raleigh for 2026

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Duke Regional Hospital hotels

A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.

A Hampton Inn hotel with a modern facade, multiple floors, and a parking lot.

A large indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls, with large windows allowing natural light.

A narrow hallway with shelves stocked with snacks and beverages, leading to a room with a desk and chair.

1. Hampton Inn & Suites Durham/North I-85

2.2 km from Duke Regional Hospital

elizabeth

￥18,798

￥21,336 total

includes taxes & fees

Sep 7 - Sep 8

2. Holiday Inn Express Durham by IHG

2.4 km from Duke Regional Hospital

Sam

￥16,079

￥18,249 total

includes taxes & fees

Aug 30 - Aug 31

A modern kitchen with a coffee machine, a stone wall with a 'Red Roof Inn' sign, and two white chairs.

A Red Roof Inn lobby with a stone wall, wooden flooring, and a seating area with chairs and a small table.

A hotel bathroom with a beige armchair, a towel rack, a mirror, and a sink.

A Red Roof Inn reception area with a stone wall, a coffee machine, and two white armchairs.

3. Red Roof Inn Durham - Duke Univ Medical Center

2.3 km from Duke Regional Hospital

Michael

￥7,864

￥9,196 total

includes taxes & fees

Sep 14 - Sep 15

A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.

A Hampton Inn & Suites hotel with a modern facade, multiple windows, and a parking lot.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

A modern dining area with a long table, multiple chairs, and a sofa with red ottomans.

4. Hampton Inn & Suites Durham University Medical Center

5 km from Duke Regional Hospital

Maggie

￥18,798

￥21,336 total

includes taxes & fees

Sep 6 - Sep 7

A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.

A bar area with a granite countertop, wooden chairs, and a large television screen.

A Hilton Garden Inn hotel with a modern design, featuring a large entrance and a parking area with a delivery van.

A business center with wooden paneling, multiple workstations, and framed artwork on the walls.

5. Hilton Garden Inn Durham/University Medical Center

9th Street District, 4 km from Duke Regional Hospital

Hal

￥23,367

￥26,522 total

includes taxes & fees

Sep 2 - Sep 3

A modern hotel reception area with two wooden reception desks, a large digital display wall, and a seating area with chairs.

A modern restaurant with bar seating, a Starbucks sign, and a bar area with a counter and shelves.

A hotel room with two beds, a desk, and a chair.

6. Hilton Durham near Duke University

5.4 km from Duke Regional Hospital

Deborah

￥16,840

￥19,114 total

includes taxes & fees

Sep 6 - Sep 7

A modern hotel with a prominent entrance, multiple floors, and a balcony on the second floor.

An outdoor patio with a fire feature, seating, and a building with large windows.

A modern dining area with wooden tables and chairs, large windows, and geometric pendant lighting.

A modern hotel room with a bed, a desk, a chair, a small seating area, and a kitchenette.

7. SpringHill Suites by Marriott Durham City View

5.4 km from Duke Regional Hospital

Dominique

￥17,727

￥20,121 total

includes taxes & fees

Aug 30 - Aug 31

A long, narrow hallway with dark walls and wooden flooring.

A hotel room with a large bed, two bedside lamps, a chair, a desk, a heater, and a window with curtains.

A compact kitchenette with a refrigerator, microwave, and a flat-screen TV on a dark cabinet.

8. University Inn Durham next to Duke University Medical Center

4.5 km from Duke Regional Hospital

Franko

￥17,651

￥20,033 total

includes taxes & fees

Aug 30 - Aug 31

An outdoor seating area with sofas, chairs, and a fire pit, adjacent to a modern building with large windows.

A modern kitchen with a central island, bar stools, wooden cabinets, and pendant lighting.

A modern living room with a fireplace, seating area, and a pool table.

A modern reception area with a marble counter, a wooden bench, and a unique chandelier.

9. JB Duke Hotel

6.2 km from Duke Regional Hospital

denise

￥23,721

￥26,924 total

includes taxes & fees

Aug 30 - Aug 31

A hotel room with a bed, a desk, a chair, a small table, a coffee machine, and a trash bin.

A Comfort Inn & Suites hotel with a modern design, featuring a prominent entrance and a landscaped front yard.

A reception area with a wooden reception desk, blue seating, a flat-screen TV, and a stone accent wall.

A swimming pool with lounge chairs and umbrellas, surrounded by a building with a clear sky.

10. Comfort Inn & Suites Durham near Duke University

Croasdaile Farm Master, 3.3 km from Duke Regional Hospital

Ngoc

￥13,882

￥15,756 total

includes taxes & fees

Sep 20 - Sep 21

An outdoor patio with wicker furniture, a stone fire pit, and a brick building in the background.

A gym with treadmills, elliptical machines, a bench press, and a blue balance board.

A hotel room with two beds, a desk, a TV, and a sofa.

A spacious lobby with a reception desk, seating area, and a beverage kiosk.

11. Residence Inn Durham McPherson/Duke University Medical Cntr

Trinity Park, 4.1 km from Duke Regional Hospital

Shelly

￥22,145

￥25,133 total

includes taxes & fees

Aug 30 - Aug 31

A hotel entrance with a stone facade, large wooden doors, and a view into the interior.

A person performing a yoga pose outdoors with trees and a golf course in the background.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and potted plants.

A dining area with a chandelier, tables, chairs, and a Christmas tree.

12. Washington Duke Inn & Golf Club

6.6 km from Duke Regional Hospital

Vicki

￥33,201

￥37,683 total

includes taxes & fees

Aug 30 - Aug 31

A modern living room with a sectional sofa, a bar area, and a dining space.

A modern hotel room with a large window, a sofa, a chair, and a coffee table with a decorative bowl.

A modern dining area with a central bar, multiple seating options, and geometric pendant lighting.

13. AC Hotel Durham

5.4 km from Duke Regional Hospital

Custom Fitness LLC.

￥23,676

￥26,871 total

includes taxes & fees

Sep 2 - Sep 3

A modern lobby with a central seating area, a TV screen, and a patterned wall.

A reception area with a counter, a welcome sign, a digital screen, and a hallway leading to a dining area.

A modern kitchen with a built-in refrigerator, a gray sofa, and a gray armchair.

A modern hotel room with a bed, bedside table, TV, and a small desk area.

14. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

18.2 km from Duke Regional Hospital

Ryan

￥18,146

￥20,550 total

includes taxes & fees

Sep 6 - Sep 7

A swimming pool with lounge chairs and a wooden fence.

A multi-story hotel with a modern design, featuring a prominent entrance with a glass canopy and an American flag.

A hotel room with a bed, a sofa, a desk with a chair, a television, and a painting on the wall.

A spacious lobby with a reception desk, seating area, and artwork on the walls.

15. Hyatt Place Durham Southpoint

16.1 km from Duke Regional Hospital

Brendan P

￥20,218

￥22,947 total

includes taxes & fees

Sep 2 - Sep 3

An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.

A multi-story hotel with a brick facade, large windows, and a well-lit entrance.

A modern restaurant with round tables and yellow chairs, a bar area, and a 'Hello Fall' sign.

A modern living room with a fireplace, two sofas, a coffee table, and a TV mounted on the wall.

16. Fairfield by Marriott Inn & Suites Durham

18.2 km from Duke Regional Hospital

Beverly

￥15,602

￥17,708 total

includes taxes & fees

Sep 10 - Sep 11

An indoor swimming pool with clear water, a no diving sign, and a seating area with chairs and tables.

A modern hotel lobby with a sectional sofa, armchairs, and a coffee table.

A modern hotel lobby with a reception desk, several chairs, a large monitor, and pendant lighting.

A modern kitchen with built-in shelves, a glass backsplash, and a variety of kitchenware.

17. Hyatt House Raleigh / RDU / Brier Creek

17.8 km from Duke Regional Hospital

Darius

￥19,486

￥22,067 total

includes taxes & fees

Aug 29 - Aug 30

An outdoor seating area with wicker chairs and a large umbrella, a fire feature, and a view of the interior through glass walls.

A kitchen with a microwave, coffee maker, and sink.

A hotel room with a large bed, a bedside table with a lamp, a TV mounted on the wall, and a window with curtains.

A swimming pool with lounge chairs and a building in the background.

18. DoubleTree Suites by Hilton Raleigh - Durham

14.2 km from Duke Regional Hospital

Victoria

￥13,838

￥15,706 total

includes taxes & fees

Sep 20 - Sep 21

An outdoor cafe with tables and chairs, umbrellas, and a bicycle parked nearby.

A spacious hotel lobby with a curved seating area, large windows, and modern lighting fixtures.

A group of people performing yoga on mats in an outdoor setting with a wooden deck and a city view in the background.

A spacious lobby with a curved ceiling, large windows, and a variety of seating arrangements including sofas, tables, and chairs.

19. The Durham Hotel

Downtown Durham, 4.5 km from Duke Regional Hospital

Laura

￥29,613

￥33,611 total

includes taxes & fees

Aug 30 - Aug 31

An outdoor seating area with a circular fire pit surrounded by wicker chairs and a table.

An indoor swimming pool with a 3 FT depth marker, a wheelchair-accessible chair, a potted plant, and a view of the outside through large windows.

A modern hotel lobby with a mix of seating areas, a bar, and a large wall-mounted TV.

A multi-story hotel with a flat facade, large windows, and a clear sky.

20. SpringHill Suites by Marriott Durham Chapel Hill

12.6 km from Duke Regional Hospital

John

￥19,626

￥22,275 total

includes taxes & fees

Aug 30 - Aug 31

View all properties

Compare popular hotels close to Duke Regional Hospital

Property	Star rating	Guest rating
Hampton Inn & Suites Durham/North I-85	9.0 Wonderful 1,011 reviews	View
Holiday Inn Express Durham by IHG	8.8 Excellent 1,010 reviews	View
Red Roof Inn Durham - Duke Univ Medical Center	6.8 1,000 reviews	View
Hampton Inn & Suites Durham University Medical Center	9.6 Exceptional 545 reviews	View
Hilton Garden Inn Durham/University Medical Center	9.2 Wonderful 1,001 reviews	View

Top Duke Regional Hospital Hotel Reviews

Courtyard Durham Near Duke University/Downtown

8/10 Good

"Everything was fine & clean other than there was no coffee in the reception even early in the morning. I have never been to a hotel that doesn't have free coffee. That was odd. Other than that, the stay was pleasant and the bed was super comfy!"

Holiday Inn Express Durham by IHG

8/10 Good

"Upon check in, I was told that I only booked one room (I booked two). After 20 minutes on the phone with Expedia, the staff member was corrected. Fire alarm went off about an hour into our stay. As people headed for the exits, the staff member at the front counter stopped everyone, said it was a false alarm. Decent options for breakfast. Pancake maker was out of order, but breakfast staff were very friendly. Comfortable beds."

Hampton Inn & Suites Durham/North I-85

10/10 Excellent

"I like All of the above. Expedia can do better with refunding my money if I'm sick, it should be as simple as me submitting a doctor's note or some other document to prove that I was sick."

University Inn Durham next to Duke University Medical Center

10/10 Excellent

"Clean , convenient location, and friendly staff."

Cottage with Yard, Mins to Duke

10/10 Excellent

"Fabulous stay! The house was comfortable and very cute. Loved the decor! Enjoyed walking around the neighborhood. Very convenient to Duke. Great communication!"

Unscripted Durham, Part of JDV by Hyatt

10/10 Excellent

"Nice rooms great location downtown. Great breakfast"

Drexall Haven - Stylish + Peaceful Stay

10/10 Excellent

"Very convenient stay for our family as we helped our daughter move into college."

Durham Retreat: Deck, Grill, Firepit, 10 mins from Duke & Downtown

10/10 Excellent

"My family & l really enjoyed our week stay at the airb&b. Nice host & really good communication. Thank u"

Family & Work Home Near Duke University & Hospitals

10/10 Excellent

"We were in Durham visiting family, and our group of 8 fit in this house perfectly. The house was well equipped and we appreciated all the little details that made it feel special. We come to Durham from time to time, and we hope to stay here again."

Frequently asked questions

What's the area like around Duke Regional Hospital?

Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.

Where is the best place to stay close to Duke Regional Hospital?

Courtyard Durham Near Duke University/Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 2.2 mi (3.5 km) from Duke Regional Hospital. Other good choices within a few miles include Comfort Inn & Suites Durham near Duke University and Holiday Inn Express Durham by IHG.

How many hotels can I expect to find near Duke Regional Hospital?

Expedia has 10 hotels and other accommodations within a mile from Duke Regional Hospital.

If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?

Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.

Where can I learn more about changing or cancelling my trip in the area near Duke Regional Hospital?

To find more details about changing or cancelling your stay near Duke Regional Hospital, click here.

What can I see and do near Duke Regional Hospital?

You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

Find hotels near Duke Regional Hospital, Raleigh from ￥9,196

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Duke Regional Hospital hotels

1. Hampton Inn & Suites Durham/North I-85

2. Holiday Inn Express Durham by IHG

3. Red Roof Inn Durham - Duke Univ Medical Center

4. Hampton Inn & Suites Durham University Medical Center

5. Hilton Garden Inn Durham/University Medical Center

6. Hilton Durham near Duke University

7. SpringHill Suites by Marriott Durham City View

8. University Inn Durham next to Duke University Medical Center

9. JB Duke Hotel

10. Comfort Inn & Suites Durham near Duke University

11. Residence Inn Durham McPherson/Duke University Medical Cntr

12. Washington Duke Inn & Golf Club

13. AC Hotel Durham

14. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

15. Hyatt Place Durham Southpoint

16. Fairfield by Marriott Inn & Suites Durham

17. Hyatt House Raleigh / RDU / Brier Creek

18. DoubleTree Suites by Hilton Raleigh - Durham

19. The Durham Hotel

20. SpringHill Suites by Marriott Durham Chapel Hill

Compare popular hotels close to Duke Regional Hospital

Top Duke Regional Hospital Hotel Reviews

Courtyard Durham Near Duke University/Downtown

Holiday Inn Express Durham by IHG

Hampton Inn & Suites Durham/North I-85

University Inn Durham next to Duke University Medical Center

Cottage with Yard, Mins to Duke

Unscripted Durham, Part of JDV by Hyatt

Drexall Haven - Stylish + Peaceful Stay

Durham Retreat: Deck, Grill, Firepit, 10 mins from Duke & Downtown

Family & Work Home Near Duke University & Hospitals

Frequently asked questions