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May 2 - May 3
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May 3 - May 4
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May 8 - May 10
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Our top choices for Downtown hotels

Free daily on-the-go breakfast

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very Good, (696 reviews)
"Very pleasant and helpful staff. Comfortable room though fairly small."
United States
William
The price is ￥13,628
￥15,988 total
includes taxes & fees
May 10 - May 11
Quality Inn Seneca Clemson Area US-123
Interior

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
7.5 km from Downtown
9.8 out of 10, Exceptional, (71 reviews)
"I have been more then once to this location and cabins are spotless, always stocked with snacks. The staff always friendly and welcoming and my dog Sammy a shepard mix enjoys the stays as well. See you next time."
United States
Stephen
The price is ￥15,509
￥23,952 total
includes taxes & fees
May 14 - May 15
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
House (3 Bedrooms) | Interior

8 Mi to Clemson: Peaceful Family Home w/ Yard

8 Mi to Clemson: Peaceful Family Home w/ Yard
3.0 star property
1.2 km from Downtown
10.0 out of 10, Exceptional, (1 review)
"The place was all out perfect the owner was polite and perfect. It was a very peaceful place to stay thank you so much."
United States
Jason
The price is ￥22,089
￥60,662 total
includes taxes & fees
May 3 - May 4
8 Mi to Clemson: Peaceful Family Home w/ Yard
Signature Cottage, 2 Bedrooms | Living room | 43-inch Smart TV with cable channels, TV, Netflix

Clemson Memorabilia House

Clemson Memorabilia House
3.0 star property
12.7 km from Downtown
9.6 out of 10, Exceptional, (10 reviews)
"We enjoyed our stay, it was the perfect size for our family of four. "
United States
Ashley
The price is ￥13,943
￥37,214 total
includes taxes & fees
May 3 - May 4
Clemson Memorabilia House
Property amenity

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
2 km from Downtown
9.4 out of 10, Exceptional, (224 reviews)
"Hotel and room were super clean. Hotel is fairly new and it shows. Nice view of Lake Keowee. Breakfast was quite good & excellent coffee. Would definitely stay there again. "
United States
Matthew
The price is ￥20,297
￥22,328 total
includes taxes & fees
May 10 - May 11
Fairfield Inn & Suites Seneca Clemson Univ Area
Front of property

Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
4.0 star property
16.3 km from Downtown
10.0 out of 10, Exceptional, (88 reviews)
"The room was spotless, the staff was accommodating, and the time spent was very relaxing. Liberty Hall feels like visiting your best friend at their beautiful historic home. Must stay when visiting the Clemson area."
United States
Ebony
The price is ￥19,770
￥29,778 total
includes taxes & fees
May 10 - May 11
Liberty Hall Bed and Breakfast
Free continental breakfast on weekdays

Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
2.0 star property
12.8 km from Downtown
7.6 out of 10, Good, (182 reviews)
"Staff was friendly. Check-in was quick, and the rooms were tidy, and the beds were comfortable."
United States
Paula
The price is ￥11,342
￥12,646 total
includes taxes & fees
May 31 - Jun 1
Rodeway Inn & Suites Walhalla
Aerial view

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
8.6 km from Downtown
9.0 out of 10, Wonderful, (1,000 reviews)
"Room was spacious and clean. Great pool. Close to campus."
United States
Melisa
The price is ￥17,076
￥21,198 total
includes taxes & fees
May 23 - May 24
Lakeside Lodge Clemson
Property amenity

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
25 km from Downtown
9.2 out of 10, Wonderful, (612 reviews)
"Clean rooms, friendly staff, great breakfast options!"
United States
Lauren
The price is ￥17,233
￥19,129 total
includes taxes & fees
May 10 - May 11
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Lobby lounge

Inn @ Clemson

Inn @ Clemson
2.5 star property
11.6 km from Downtown
8.0 out of 10, Very Good, (999 reviews)
"Very clean. Loved the room. Staff was very friendly. Definately staying here again"
United States
Leanne
The price is ￥12,841
￥14,253 total
includes taxes & fees
May 3 - May 4
Inn @ Clemson
Standard Room, 1 King Bed, Non Smoking, Jetted Tub | Desk, laptop workspace, blackout drapes, iron/ironing board

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
1.7 km from Downtown
8.4 out of 10, Very Good, (655 reviews)
"Room was clean and staff was very efficient. "
United States
Judith
The price is ￥14,649
￥16,115 total
includes taxes & fees
May 13 - May 14
Best Western Seneca-Clemson
Front of property

Woodspring Suites Anderson North I-85

Woodspring Suites Anderson North I-85
2.5 star property
25.4 km from Downtown
7.6 out of 10, Good, (129 reviews)
"Lovely rooms and lovely area"
United States
Nehal
The price is ￥11,906
￥13,216 total
includes taxes & fees
May 19 - May 20
Woodspring Suites Anderson North I-85
Lobby

Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
24.8 km from Downtown
8.2 out of 10, Very Good, (1,002 reviews)
"Front desk staff were very friendly. We had a welcoming and quiet 1 night stay."
United States
Nicole
The price is ￥13,212
￥14,666 total
includes taxes & fees
May 27 - May 28
Microtel Inn & Suites by Wyndham Anderson/Clemson
Golf

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
10.3 km from Downtown
9.4 out of 10, Exceptional, (1,001 reviews)
"Friendly staff, room clean, great coffee at front desk! Beautiful views of golf course and lake."
United States
gina
The price is ￥15,544
￥17,254 total
includes taxes & fees
May 11 - May 12
Clemson University's James F. Martin Inn
In-room safe, blackout drapes, iron/ironing board, free WiFi

Holiday Inn Anderson by IHG

Holiday Inn Anderson by IHG
3.0 star property
29.5 km from Downtown
8.8 out of 10, Excellent, (724 reviews)
"Clean, great breakfast and friendly staff"
United States
Doris
The price is ￥17,271
￥19,171 total
includes taxes & fees
May 10 - May 11
Holiday Inn Anderson by IHG
Hallway

Hampton Inn & Suites Lavonia

Hampton Inn & Suites Lavonia
2.5 star property
30.7 km from Downtown
9.0 out of 10, Wonderful, (403 reviews)
"The hotel was very clean. I stayed on the 2nd floor, and the carpets seemed brand new. Staff was super helpful."
United States
Tina
The price is ￥19,484
￥23,192 total
includes taxes & fees
May 21 - May 22
Hampton Inn & Suites Lavonia
Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency) | Premium bedding, individually decorated, desk, laptop workspace

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
11.7 km from Downtown
8.2 out of 10, Very Good, (1,003 reviews)
"Great breakfast and friendly staff made our stay enjoyable."
United States
Lon
The price is ￥16,966
￥18,832 total
includes taxes & fees
May 25 - May 26
Comfort Inn & Suites Clemson - University Area
Hallway

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
15.2 km from Downtown
9.8 out of 10, Exceptional, (842 reviews)
"Very nice hotel - very clean, beautiful decor."
United States
Elizabeth
The price is ￥24,965
￥27,712 total
includes taxes & fees
May 3 - May 4
The Inn at Patrick Square
Outdoor pool, open 9:00 AM to 9:00 PM, sun loungers

Fairfield Inn & Suites by Marriott Anderson Clemson

Fairfield Inn & Suites by Marriott Anderson Clemson
3.0 star property
25 km from Downtown
9.0 out of 10, Wonderful, (571 reviews)
"Staff at the desk was absolutely fantastic! "
United States
Brooke A
The price is ￥13,253
￥14,712 total
includes taxes & fees
May 17 - May 18
Fairfield Inn & Suites by Marriott Anderson Clemson
Free breakfast

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
11.8 km from Downtown
8.2 out of 10, Very Good, (1,005 reviews)
"Clean rooms, nice staff, free breakfast"
United States
Jeff
The price is ￥17,216
￥19,111 total
includes taxes & fees
May 27 - May 28
Best Western Plus Clemson Hotel & Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Downtown

Find the best Downtown areas and neighborhoods for the activities you enjoy most.

Serenity Bay

Though Serenity Bay might not have many top sights, you can venture to the surrounding area to see attractions like Keowee Key Golf Course and Lake Keowee.

Female Kayaker on Lake Keowee at Sunset

Pine Ridge Point

While Pine Ridge Point isn't home to many top sights, Lake Keowee and Keowee Key Golf Course are some notable places to visit nearby.

Indian Oaks

While there might not be top attractions in Indian Oaks, you can explore the larger area and discover places like Oconee County Library Seneca Branch and Seneca Historic District.

Keowee Plantation

When in Keowee Plantation, you can plan a visit to Oconee County Library Seneca Branch and Seneca Historic District, some noteworthy sights in the nearby area.

Top Downtown Hotel Reviews

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

10/10 Excellent
"Clean property. Wide variety for breakfast."
Lorna 1-night trip
Posted 6 hours ago
Best Western Plus Clemson Hotel & Conference Center

Frequently asked questions

What is Downtown like?
Travelers to the Downtown neighborhood in Seneca will be sure to enjoy their stay. Be sure to check out Seneca Historic District and Oconee County Library Seneca Branch as part of your Downtown travel plans.
Where is the best place to stay in Downtown?
Based on our traveler data, Quality Inn Seneca Clemson Area US-123 is one of the top choices for your stay in Downtown. This hotel offers free breakfast and free parking.
How many hotels can I expect to find in Downtown?
If you're searching for places to stay in Seneca, choose from one of Expedia's 13 hotels and other accommodations in Downtown.
If I need to cancel my hotel reservation in Downtown, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to view the best deals in Downtown.
Where can I learn more about changing or cancelling my trip to Downtown?
To find more details about rescheduling or cancelling your trip to Downtown, head over to our customer service page.
What can I see and do in this Seneca neighborhood?
Seneca Historic District, Oconee County Library Seneca Branch, and Blue Ridge Arts Center are just a few attractions to check out in Downtown. As you're discovering the neighborhood, Bertha Lee Strickland Cultural Museum and The Gauntlet are some other places worth a visit. Seneca City Hall, Golden Corner Plaza, and Oconee Community Theatre are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, be sure to visit other sights like Applewood Shopping Center or Wyndham Plaza.