Depew Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Jun 19 - Jun 21
In two months
Jul 31 - Aug 2
In three months
Aug 28 - Aug 30
In four months
Sep 25 - Sep 27

Our top choices for Depew vacation rentals

Interior

Tiny Spa Cottage Retreat

Tiny Spa Cottage Retreat
Alden
9.8 out of 10, Exceptional, (120 reviews)
"Everything about this tiny cottage was perfect. I was looking for a quiet relaxing long weekend away from work & couldnt have asked for more."
United States
MELODY K.
The price is ￥19,235
￥32,780 total
includes taxes & fees
Jun 12 - Jun 13
Tiny Spa Cottage Retreat
1 bedroom, free WiFi

ADA Studio 6 Buffalo|Queen Bed|RI Shower|Nsmk Kitchen

ADA Studio 6 Buffalo|Queen Bed|RI Shower|Nsmk Kitchen
Buffalo NY
10.0 out of 10, Exceptional, (42 reviews)
"Great hotel clean and kitchen"
United States
Anonymous traveler
The price is ￥13,961
￥15,880 total
includes taxes & fees
Jul 1 - Jul 2
ADA Studio 6 Buffalo|Queen Bed|RI Shower|Nsmk Kitchen
Exterior

Cozy Cuddler's Cottage

Cozy Cuddler's Cottage
West Falls
9.8 out of 10, Exceptional, (9 reviews)
"Awesome location. Friendly staff. Great value and close to family!!"
United States
Bill
The price is ￥16,029
￥40,483 total
includes taxes & fees
Jun 8 - Jun 9
Cozy Cuddler's Cottage
Interior

Spacious kid friendly apt near East Aurora

Spacious kid friendly apt near East Aurora
West Falls
10.0 out of 10, Exceptional, (11 reviews)
"Great stay in a great location. "
United States
Anonymous traveler
The price is ￥20,036
￥46,035 total
includes taxes & fees
Jun 9 - Jun 10
Spacious kid friendly apt near East Aurora
Smart TV

Luxury Villa

Luxury Villa
Lancaster
9.8 out of 10, Exceptional, (16 reviews)
"Really enjoyed my stay! They made us very comfortable and let us check in early due to our early flight 10/10 come check it out "
United States
Da’Lisha P.
The price is ￥21,351
￥30,130 total
includes taxes & fees
Jun 9 - Jun 10
Luxury Villa
Spa

Cozy 3-bedroom house in charming Buffalo with WiFi, AC

Cozy 3-bedroom house in charming Buffalo with WiFi, AC
Kaisertown
8.4 out of 10, Very Good, (15 reviews)
"Enjoyed the stay! "
United States
Jamie M.
The price is ￥16,590
￥30,994 total
includes taxes & fees
Jun 8 - Jun 9
Cozy 3-bedroom house in charming Buffalo with WiFi, AC
1 bedroom, free WiFi

Studio 6 Buffalo|Cozy 2 Full Beds,Nsmk|Kitchen

Studio 6 Buffalo|Cozy 2 Full Beds,Nsmk|Kitchen
Buffalo NY
10.0 out of 10, Exceptional, (48 reviews)
"good place to stay"
United States
Anonymous traveler
The price is ￥14,755
￥16,783 total
includes taxes & fees
Jul 1 - Jul 2
Studio 6 Buffalo|Cozy 2 Full Beds,Nsmk|Kitchen
Fridge, microwave, oven, stovetop

Suite Retreat: quiet comfort on walkable village lane

Suite Retreat: quiet comfort on walkable village lane
Akron
10.0 out of 10, Exceptional, (11 reviews)
"Easy check in process, very clean property with thoughtful touches and amenities that exceed expectations."
United States
Kellerie
The price is ￥23,803
￥47,380 total
includes taxes & fees
Jun 9 - Jun 10
Suite Retreat: quiet comfort on walkable village lane
Interior

Charming 2-bedroom apartment in Pleasant Blasdell with morning breakfast.

Charming 2-bedroom apartment in Pleasant Blasdell with morning breakfast.
Blasdell
9.8 out of 10, Exceptional, (7 reviews)
"The place was fairly clean. Well stocked and the hosts were incredibly nice! "
United States
Matthew
The price is ￥23,803
￥46,482 total
includes taxes & fees
Jun 8 - Jun 9
Charming 2-bedroom apartment in Pleasant Blasdell with morning breakfast.
4 bedrooms, WiFi, bed sheets

Don’t miss out on the opportunity to stay in the 12thManMisfitzManor

Don’t miss out on the opportunity to stay in the 12thManMisfitzManor
Orchard Park
9.8 out of 10, Exceptional, (28 reviews)
"Such a fun spot! "
United States
Jamie F.
The price is ￥16,301
￥45,443 total
includes taxes & fees
Jun 15 - Jun 16
Don’t miss out on the opportunity to stay in the 12thManMisfitzManor
Seasonal outdoor pool

Regency Retreat

Regency Retreat
3.0 star property
Lockport
The price is ￥51,293
￥69,982 total
includes taxes & fees
Jun 25 - Jun 26
Regency Retreat
Smart TV

Niagara Falls is only 30minutes away.Airport 4 min away. Family & pet friendly!

Niagara Falls is only 30minutes away.Airport 4 min away. Family & pet friendly!
Buffalo
9.8 out of 10, Exceptional, (27 reviews)
"Nice accommodation for the cost with host being responsive with any questions we had along with any requests.We would recommend to anyone and will stay again when in the area."
United States
Aimee R.
The price is ￥19,235
￥32,243 total
includes taxes & fees
Jun 8 - Jun 9
Niagara Falls is only 30minutes away.Airport 4 min away. Family & pet friendly!
Exterior

Nice house with private parking, king bed fenced yard

Nice house with private parking, king bed fenced yard
West Seneca
8.8 out of 10, Excellent, (10 reviews)
"Yes suitable for pets. Kitchen had what we needed. We very much enjoyed our stay, immaculate condition. "
United States
Sean
The price is ￥25,005
￥59,572 total
includes taxes & fees
Jun 15 - Jun 16
Nice house with private parking, king bed fenced yard
Dining

420 Friendly 3 bedroom upstairs apartment. Street parking only.

420 Friendly 3 bedroom upstairs apartment. Street parking only.
Seneca
9.4 out of 10, Exceptional, (72 reviews)
"Excellent stay! All the things we needed and then some :) highly recommend! Will be staying here anytime I am in the area!"
United States
Kerry G.
The price is ￥21,158
￥30,014 total
includes taxes & fees
Jun 8 - Jun 9
420 Friendly 3 bedroom upstairs apartment. Street parking only.
Property grounds

‘Turtle Cove Bay Beach House’ ~ 13 Mi to Buffalo!

‘Turtle Cove Bay Beach House’ ~ 13 Mi to Buffalo!
Lake View
9.8 out of 10, Exceptional, (23 reviews)
"We had a great family stay at the Turtle Cove Beach house. The owner was very proactive on communication and making sure our stay met all our needs."
United States
Jim W.
‘Turtle Cove Bay Beach House’ ~ 13 Mi to Buffalo!
Interior

2-bedroom House in beautiful Grand Island,NY! 4 miles from Niagara Falls!

2-bedroom House in beautiful Grand Island,NY! 4 miles from Niagara Falls!
Grand island
9.8 out of 10, Exceptional, (18 reviews)
"Accomodations were great"
United States
Ginny A.
The price is ￥20,517
￥41,377 total
includes taxes & fees
Jun 11 - Jun 12
2-bedroom House in beautiful Grand Island,NY! 4 miles from Niagara Falls!
Fridge, microwave, oven, stovetop

Delightful dwelling

Delightful dwelling
Elmwood Bidwell
10.0 out of 10, Exceptional, (2 reviews)
"The host is very friendly and accommodating. The unit is very nice, private and quite. The neighborhood is safe with resturants and shops within 15 minutes walk. Highly recommend this unit."
United States
Nasser K.
The price is ￥22,841
￥50,307 total
includes taxes & fees
Jun 14 - Jun 15
Delightful dwelling
Fridge, microwave, stovetop, dishwasher

Pet-Friendly Lancaster Home 13 Mi to Dtwn Buffalo

Pet-Friendly Lancaster Home 13 Mi to Dtwn Buffalo
Lancaster
10.0 out of 10, Exceptional, (30 reviews)
"It was great stay"
United States
Vomshankar R.
The price is ￥24,524
￥68,671 total
includes taxes & fees
Jun 16 - Jun 17
Pet-Friendly Lancaster Home 13 Mi to Dtwn Buffalo
House (3 Bedrooms) | Interior

Pet-friendly Lancaster Home 13 Mi to Dtwn Buffalo

Pet-friendly Lancaster Home 13 Mi to Dtwn Buffalo
3.0 star property
Lancaster
The price is ￥29,814
￥71,116 total
includes taxes & fees
Jul 6 - Jul 7
Pet-friendly Lancaster Home 13 Mi to Dtwn Buffalo
1 bedroom, free WiFi, bed sheets

4-Guest Suite in Beautiful Grand Island, NY! 4 miles from Niagara Falls!

4-Guest Suite in Beautiful Grand Island, NY! 4 miles from Niagara Falls!
Grand island
10.0 out of 10, Exceptional, (9 reviews)
"Nice welcoming amenities, is walking distance to a restaurant, and only a few minute drive to Casino and Niagara Falls. "
United States
Denise P.
The price is ￥15,869
￥30,452 total
includes taxes & fees
Jun 8 - Jun 9
4-Guest Suite in Beautiful Grand Island, NY! 4 miles from Niagara Falls!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Depew Hotel Reviews

Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

10/10 Excellent
"Every thing was perfect"
Tim 4-night trip
Posted 1 hour ago
Sleep Inn & Suites Buffalo Airport

Find out more about Depew

Search for holiday rentals in Depew on Expedia! You can easily find your home rentals, villas, holiday apartments in Depew using one of the methods below:

  • View our selection of featured holiday rentals in Depew
  • Use the map to find apartments and other holiday homes in the Depew neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in Depew while they last

Look no further and take a look at our great range of rental properties in Depew!

Frequently asked questions

Can I find vacation rentals in Depew?

Yes, we have vacation rentals near well known sights in Depew, or you can choose a secluded option if you're looking for relaxation. Depew is known for its shopping and restaurants. Make sure you have time to check out the sporting events and waterfalls during your trip.

What are some of the best vacation home rentals in Depew?

HTR Niagara: Visitors like this Depew vacation home rental. It is on the riverwalk and equipped with air-conditioning and free WiFi to help you feel perfectly comfortable in your new surroundings. Amenities like a coffee maker and free parking are also available for your convenience.

How many vacation rentals will I find in Depew?

Choose from 6 Expedia vacation rentals in Depew for a memorable vacation.

What can I see and do in Depew?

While exploring the area, visit family-friendly sights like Six Flags Darien Lake, or get outside and enjoy nature at Glen Falls. Highmark Stadium and Walden Galleria Mall are a couple of places you'll find in the larger area.

What are vacation rentals like in Depew?

Vacation rentals are private accommodations you can reserve for several days or more in Depew. Vacation rentals feature extras like WiFi and washers and dryers so you'll have everything you want. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from shared hotel elevators and busy lobbies while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a standard hotel, which makes a vacation rental a great option for a family trip.