Find hotels in Depew, NY from ￥10,695

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Dec 10 - Dec 11
Tomorrow
Dec 11 - Dec 12
This weekend
Dec 12 - Dec 14
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Dec 19 - Dec 21

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Our top choices for Depew hotels

Lobby
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport
2.5 star property
Buffalo
8.0 out of 10, Very Good, (1885)
"Clean facility, friendly staff, convenient location, overall nice stay."
Canada
Kris
The price is ￥11,144
￥12,677 total
includes taxes & fees
Dec 30 - Dec 31
Sleep Inn & Suites Buffalo Airport
Reception hall
M Hotel Buffalo

M Hotel Buffalo

M Hotel Buffalo
3.5 star property
Buffalo
7.4 out of 10, Good, (2522)
"Clean rooms, good breakfast, check in process was quick."
United States
Chris
The price is ￥13,881
￥15,789 total
includes taxes & fees
Dec 29 - Dec 30
M Hotel Buffalo
Reception
Garden Place Hotel

Garden Place Hotel

Garden Place Hotel
3.5 star property
Buffalo
7.8 out of 10, Good, (2132)
"A lovely hotel close to the airport. "
United States
Jasmine
Garden Place Hotel
Lobby
Comfort Inn University

Comfort Inn University

Comfort Inn University
2.5 star property
Buffalo
8.0 out of 10, Very Good, (1204)
"Good place to stay and rest "
United States
Luis
The price is ￥15,481
￥17,611 total
includes taxes & fees
Dec 30 - Dec 31
Comfort Inn University
Indoor pool
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center
3.5 star property
Downtown Buffalo
8.2 out of 10, Very Good, (1668)
"awesome and great location, staff was great, they really make us feel welcome, i really enjoyed here, "
United States
franklin
The price is ￥19,731
￥23,036 total
includes taxes & fees
Dec 29 - Dec 30
Hyatt Regency Buffalo / Hotel and Conference Center
Exterior
La Quinta Inn by Wyndham Buffalo Airport

La Quinta Inn by Wyndham Buffalo Airport

La Quinta Inn by Wyndham Buffalo Airport
3.0 star property
Buffalo
8.0 out of 10, Very Good, (1345)
"Rooms were clean… staff was nice… breakfast was good…. Dinner at the anchor bar right next store almost in the same parking lot "
Canada
Chad
The price is ￥11,863
￥13,494 total
includes taxes & fees
Dec 19 - Dec 20
La Quinta Inn by Wyndham Buffalo Airport
Exterior
Hampton Inn Buffalo - Amherst, NY

Hampton Inn Buffalo - Amherst, NY

Hampton Inn Buffalo - Amherst, NY
2.5 star property
Buffalo
9.4 out of 10, Exceptional, (1989)
"The room was very clean and the location was very convenient."
United States
Lee
The price is ￥16,078
￥18,289 total
includes taxes & fees
Dec 25 - Dec 26
Hampton Inn Buffalo - Amherst, NY
Exterior
Hyatt Place Buffalo/Amherst

Hyatt Place Buffalo/Amherst

Hyatt Place Buffalo/Amherst
3.0 star property
Buffalo
9.0 out of 10, Wonderful, (1097)
"Only place I stay. Always a great experience and clean rooms!"
United States
Linda
The price is ￥23,860
￥27,140 total
includes taxes & fees
Dec 12 - Dec 13
Hyatt Place Buffalo/Amherst
Premium bedding, in-room safe, desk, blackout drapes
Holiday Inn Express Grand Island - Niagara Falls by IHG

Holiday Inn Express Grand Island - Niagara Falls by IHG

Holiday Inn Express Grand Island - Niagara Falls by IHG
2.5 star property
Grand Island
8.8 out of 10, Excellent, (1596)
"Clean room, staff, amenities, and breakfast; everything is excellent and budget-worthy. "
United States
Mohana Raju
The price is ￥11,596
￥13,191 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Holiday Inn Express Grand Island - Niagara Falls by IHG
Indoor pool
Sleep Inn Amherst - Buffalo North near University

Sleep Inn Amherst - Buffalo North near University

Sleep Inn Amherst - Buffalo North near University
2.5 star property
Buffalo
8.8 out of 10, Excellent, (1136)
"Staff is friendly, stores close.by, and hot tub was bubbly"
United States
Tina
The price is ￥12,909
￥14,685 total
includes taxes & fees
Dec 30 - Dec 31
Sleep Inn Amherst - Buffalo North near University
Courtyard view
Buffalo Airport Hotel

Buffalo Airport Hotel

Buffalo Airport Hotel
3.0 star property
Buffalo
8.0 out of 10, Very Good, (2764)
"Nice place to stay in "
United States
Dey
The price is ￥10,328
￥11,748 total
includes taxes & fees
Dec 11 - Dec 12
Buffalo Airport Hotel
Free daily continental breakfast
Quality Inn Near Walden Galleria Mall

Quality Inn Near Walden Galleria Mall

Quality Inn Near Walden Galleria Mall
2.5 star property
Buffalo
8.0 out of 10, Very Good, (1016)
"Friendly staff, easy parking"
United States
Brittany
The price is ￥13,108
￥14,910 total
includes taxes & fees
Dec 25 - Dec 26
Quality Inn Near Walden Galleria Mall
2 restaurants, dinner served
The Delavan Hotel & Spa

The Delavan Hotel & Spa

The Delavan Hotel & Spa
4.0 star property
Bowmansville
8.8 out of 10, Excellent, (1000)
"Great location. Very spacious hotel, including the bathrooms. Friendly staff. Fun place to stay. "
United States
Michael
The Delavan Hotel & Spa
Lobby
La Quinta Inn & Suites by Wyndham Buffalo Amherst

La Quinta Inn & Suites by Wyndham Buffalo Amherst

La Quinta Inn & Suites by Wyndham Buffalo Amherst
3.0 star property
Buffalo
8.6 out of 10, Excellent, (1959)
"The building was so nice and clean and so was the room. The staff was so nice. We really enjoyed the stay and will stay there again. "
United States
Jennifer
The price is ￥11,997
￥13,647 total
includes taxes & fees
Dec 30 - Dec 31
La Quinta Inn & Suites by Wyndham Buffalo Amherst
Property entrance
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
2.5 star property
Buffalo
8.2 out of 10, Very Good, (1004)
"It was a short, but nice stay."
United States
Sheila
The price is ￥13,016
￥14,807 total
includes taxes & fees
Dec 23 - Dec 24
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
Exterior
Hampton Inn & Suites Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown
2.5 star property
Downtown Buffalo
8.8 out of 10, Excellent, (1003)
"Great location. Parking available. Good breakfast. "
United States
Carmen
The price is ￥19,947
￥23,288 total
includes taxes & fees
Dec 17 - Dec 18
Hampton Inn & Suites Buffalo Downtown
Exterior
Holiday Inn Express Cheektowaga North East by IHG

Holiday Inn Express Cheektowaga North East by IHG

Holiday Inn Express Cheektowaga North East by IHG
2.5 star property
Buffalo
8.4 out of 10, Very Good, (1203)
"The lady at the desk (check-in and check-out) was so nice and friendly."
Canada
Maryam
The price is ￥15,212
￥17,304 total
includes taxes & fees
Dec 14 - Dec 15
Holiday Inn Express Cheektowaga North East by IHG
Front of property - evening/night
Aloft Buffalo Airport

Aloft Buffalo Airport

Aloft Buffalo Airport
3.0 star property
Buffalo
8.0 out of 10, Very Good, (1001)
"Excellent, friendly staff!"
United States
Matthew
The price is ￥14,068
￥16,549 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Aloft Buffalo Airport
Desk, blackout drapes, iron/ironing board, free cribs/infant beds
Best Western Galleria Inn & Suites

Best Western Galleria Inn & Suites

Best Western Galleria Inn & Suites
2.5 star property
Buffalo
6.6 out of 10, (1001)
"They were fantastic from check-in through our stay right to check out top notch clean friendly it was a great stay"
United States
Philippe
The price is ￥13,241
￥15,061 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Best Western Galleria Inn & Suites
Terrace/patio
Candlewood Suites Buffalo - Amherst by IHG

Candlewood Suites Buffalo - Amherst by IHG

Candlewood Suites Buffalo - Amherst by IHG
2.5 star property
Buffalo
8.6 out of 10, Excellent, (951)
"WE LOVE THIS HOTEL! The staff is always amazing and always so willing to help when needed. The rooms are always clean, and no bad smell anywhere in the hotel. The rooms come with just about anything you would need but the front desk has a borrow locker if needed. Good safe area, lots to do around. Seriously can't say enough good things about this hotel!!"
United States
Andrew
The price is ￥15,368
￥17,482 total
includes taxes & fees
Dec 23 - Dec 24
Candlewood Suites Buffalo - Amherst by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Depew Hotel Reviews

M Hotel Buffalo

M Hotel Buffalo

10/10 Excellent
"Was great experience Once again ! "
Derek 2-night trip
Posted 23 hours ago
M Hotel Buffalo

More cheap stays in Depew

CenterWay Hotel Tonawanda

CenterWay Hotel Tonawanda

225 Crestmount Avenue Tonawanda NY
The price is ￥9,401 per night from Dec 11 to Dec 12
￥9,401
￥10,695 total
Dec 11 - Dec 12
includes taxes & fees
7.8/10 Good! (1,004 reviews)

Frequently asked questions

What's the best place for a stay in Depew?
Located 8.6 mi (13.9 km) from the heart of Depew, Hyatt Regency Buffalo / Hotel and Conference Center is a top choice for your stay based on our traveler data. Two other choices for your visit to the area are Garden Place Hotel and Buffalo Airport Hotel. See all available top hotels, or vacation rentals in Depew.
What's the top vacation rental in Depew?
Cozy Buffalo Getaway – Minutes to Downtown & Bills Stadium: This vacation home rental outside of Depew has air-conditioning and WiFi to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. See all vacation rentals in Depew.
If I need to cancel my hotel reservation in Depew, will I receive a refund?
Yes! Most hotel bookings are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Depew.
Where can I learn more about changing or cancelling my trip to Depew?
For more information about picking new dates or cancelling your trip to Depew, click here.
What are some accommodations with pools in Depew?
Hyatt Regency Buffalo / Hotel and Conference Center: Hotel located near KeyBank Center. Features complimentary wireless internet access, an indoor pool, and a 24-hour fitness center. M Hotel Buffalo and Days Inn & Suites by Wyndham Niagara Falls/Buffalo are a couple of other choices that feature an onsite pool. View all hotels with pools in Depew.
What's the best place to stay near Buffalo Niagara International Airport (BUF)?
Days Hotel by Wyndham Buffalo Airport is a popular 3-star hotel featuring free breakfast and a restaurant. It's located a short 0.3 mi (0.5 km) from Buffalo Niagara Intl. Airport. Other places to stay within close proximity to the airport include Hilton Garden Inn Buffalo Airport and Courtyard Buffalo Airport.
What is staying in Depew like?
Visitors can enjoy all that Depew has to offer including the shopping, restaurants, and sporting events. Tourists can also enjoy so much more including its waterfalls. In Depew, there are 12 hotels and other accommodations to choose from. Find out more about Depew.
What are the top places to visit in Depew?
Places to visit in the wider area include Holiday Twin Rinks, Walden Galleria Mall, and Samuel's Grande Manor. You'll also find Glen Falls and Buffalo Central Terminal in the area. Check out what more to see and do in Expedia's Depew guide.
How should I get around Depew?
To see more of the larger area, ride aboard one of the trains from Buffalo-Depew Station. If you want to venture out around the area, you may want a rental car in Depew for your journey.
What's the weather like in Depew?
The hottest months are usually July and August with an average temp of 67°F, while the coldest months are January and February with an average of 29°F. The snowiest months in Depew are January, March, February, and December, with each month seeing an average of 17 inches of snowfall.

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