A street lined with historic buildings, palm trees, and a church tower with a clock.

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Check availability on Daniel Island Business Hotels

Tonight
Oct 20 - Oct 21
Tomorrow
Oct 21 - Oct 22
This weekend
Oct 23 - Oct 25
Next weekend
Oct 30 - Nov 1

Our top choices for Daniel Island business-friendly hotels

An outdoor patio area with a fire pit, seating, and a covered section.
A modern hotel room with a kitchenette, a bed, a desk, and a television.
A modern kitchen area with a coffee station featuring three coffee makers labeled 'GOURMET,' 'DECAF,' and 'HOT WATER.' There is a stone pillar and a sign on the wall that reads 'HOMER.'
A swimming pool with lounge chairs, a pergola, and a brick building with large windows.

1. Home2 Suites by Hilton Charleston Daniel Island

Home2 Suites by Hilton Charleston Daniel Island
Charleston
United States
Layla
￥20,667
￥23,562 total
includes taxes & fees
Nov 1 - Nov 2
Home2 Suites by Hilton Charleston Daniel Island
A swimming pool with lounge chairs and umbrellas, surrounded by trees and a building with multiple windows.
A hotel room with a sofa, two beds, a desk, and a window with a view.
A modern living room with a sectional sofa, a coffee table, a chair, and a flat-screen TV mounted on the wall.
A modern hotel room with a flat-screen TV, a wooden dresser, a blue sofa, a desk with a chair, and a painting on the wall.

2. Holiday Inn Express & Suites Mt. Pleasant by IHG

Holiday Inn Express & Suites Mt. Pleasant by IHG
Mount Pleasant
United States
Naomi
￥14,741
￥17,018 total
includes taxes & fees
Oct 25 - Oct 26
Holiday Inn Express & Suites Mt. Pleasant by IHG
A covered outdoor area with a pool, palm trees, and lounge chairs.
A spacious restaurant with high ceilings, exposed beams, and a brick fireplace. Tables are arranged in a U-shape around the fireplace, with hanging pendant lights above.
A covered outdoor lounge area with wicker furniture, a pool, and a view of the beach and marina.
A beachside walkway with bicycles, colorful chairs, and palm trees.

3. The Beach Club at Charleston Harbor Resort and Marina

The Beach Club at Charleston Harbor Resort and Marina
Mount Pleasant
United States
Robert
￥25,550
￥36,394 total
includes taxes & fees
Nov 17 - Nov 18
The Beach Club at Charleston Harbor Resort and Marina
A pool area with lounge chairs and palm trees.
A modern restaurant with a long counter, multiple dining tables, and a seating area with sofas.
A hotel outdoor seating area with wicker chairs, a pool, and palm trees.
A modern kitchen with a central island, built-in shelves, and a variety of kitchen appliances.

4. Hotel Indigo Mount Pleasant by IHG

Hotel Indigo Mount Pleasant by IHG
Mount Pleasant
United States
Mary Beth
￥16,802
￥22,155 total
includes taxes & fees
Nov 17 - Nov 18
Hotel Indigo Mount Pleasant by IHG
A modern bar area with a wooden ceiling, bar stools, and a counter.
A modern kitchen with a Keurig coffee maker, a coffee station, a large mirror, and artwork on the wall.
A gym with treadmills, weight machines, and a mirror.
A modern lobby with a curved wooden wall, a central seating area with a blue sofa, and a large framed artwork on the wall.

5. Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston
Mount Pleasant
United States
william
￥17,382
￥19,812 total
includes taxes & fees
Nov 16 - Nov 17
Cambria Hotel Mount Pleasant – Charleston
A hotel lobby with a bar area, multiple dining tables, and chairs.
A rooftop patio with outdoor seating, a fire pit, and a view of a multi-story building with balconies.
A modern kitchen with a central island, bar stools, and a variety of kitchen appliances.
A spacious lobby with a high ceiling, a staircase with a wooden handrail, and a seating area with patterned cushions.

6. Hilton Garden Inn Charleston / Mt. Pleasant

Hilton Garden Inn Charleston / Mt. Pleasant
Mount Pleasant
United States
Katie
￥18,728
￥21,162 total
includes taxes & fees
Nov 1 - Nov 2
Hilton Garden Inn Charleston / Mt. Pleasant
A pool table in a lounge area with a mural in the background.
A hydration station with a water dispenser and a reusable bottle refill station, a treadmill, and a mirror reflecting the room.
A hotel room with a large bed, a nightstand, a red side table, and a modern lamp.
A breakfast station with bagels, donuts, and English muffins.

7. Tru by Hilton Mt Pleasant Charleston

Tru by Hilton Mt Pleasant Charleston
Mount Pleasant
United States
Pamela
￥16,572
￥19,045 total
includes taxes & fees
Nov 17 - Nov 18
Tru by Hilton Mt Pleasant Charleston
A modern kitchen with a large island, bar stools, framed pictures on the wall, and a view of the outside.
A reception desk with a wooden finish, a tiled ceiling with recessed lighting, and a patterned wall to the right.
A hotel with a swimming pool, outdoor seating, and a gazebo.
A hotel room with a bed, desk, chair, television, and a mirror.

8. Quality Inn Mt. Pleasant - Charleston

Quality Inn Mt. Pleasant - Charleston
Mount Pleasant
United States
Russell
￥13,763
￥15,869 total
includes taxes & fees
Nov 15 - Nov 16
Quality Inn Mt. Pleasant - Charleston
A spacious lobby with a high ceiling, a mezzanine level, and multiple seating areas including sofas and chairs.
A pool area with lounge chairs and a brick building in the background.
A clean, well-lit breakfast area with wooden cabinets, a coffee machine, and a microwave.
A two-story building with a covered entrance, palm trees, and a well-maintained lawn.

9. Comfort Inn & Suites Patriots Point

Comfort Inn & Suites Patriots Point
Mount Pleasant
United States
Trevor
￥16,674
￥18,842 total
includes taxes & fees
Nov 10 - Nov 11
Comfort Inn & Suites Patriots Point
A bar area with a curved counter, multiple seating options including round tables and chairs, and a patterned floor.
A modern hotel lobby with a round seating area, a chandelier, and a patterned floor.
A lobby with a central seating area, a chandelier, and framed pictures on the walls.
A hallway with a patterned carpet, a modern chandelier, and an elevator.

10. DoubleTree by Hilton Charleston Mount Pleasant

DoubleTree by Hilton Charleston Mount Pleasant
Mount Pleasant
United States
Paul
￥15,593
￥17,936 total
includes taxes & fees
Nov 16 - Nov 17
DoubleTree by Hilton Charleston Mount Pleasant
View all properties

Top Daniel Island Hotel Reviews

Hotel Indigo Mount Pleasant by IHG

Hotel Indigo Mount Pleasant by IHG

10/10 Excellent
"Very impressed with cleanliness of property. Room very spacious and layer out well. Loved the toiletries ."
Kenneth 1-night trip
Posted 10 hours ago
Hotel Indigo Mount Pleasant by IHG
Drury Plaza Hotel North Charleston

Drury Plaza Hotel North Charleston

10/10 Excellent
"Overall great place to stay."
Cory 2-night trip
Posted 16 hours ago
Drury Plaza Hotel North Charleston
Harborside at Charleston Harbor Resort and Marina

Harborside at Charleston Harbor Resort and Marina

10/10 Excellent
"Greatest stay we have ever had. Just sit by the water. Incredible. Everyone is great."
Ernest M. 1-night trip
Posted 16 hours ago
Harborside at Charleston Harbor Resort and Marina
Tides Folly Beach, Charleston's Oceanfront Hotel

Tides Folly Beach, Charleston's Oceanfront Hotel

10/10 Excellent
"I have stayed here several times. Very convenient and close to all the shops. The vibe is amazing!!!"
Cassandra 1-night trip
Posted 18 hours ago
Tides Folly Beach, Charleston's Oceanfront Hotel
Holiday Inn Express & Suites Charleston DWTN - Medical CTR by IHG

Holiday Inn Express & Suites Charleston DWTN - Medical CTR by IHG

8/10 Good
"The overnight parking was a problem. No enough space."
Nasrin 2-night trip
Posted 22 hours ago
Holiday Inn Express & Suites Charleston DWTN - Medical CTR by IHG
The Charleston Place

The Charleston Place

10/10 Excellent
"To have a luxury hotel like this that is privately owned and not a massive corporate feel is awesome. We love the Charleston place and all the changes they have been making over the past few years. Beautiful property great vibe and quiet luxury."
Kristopher 2-night trip
Posted 2 days ago
The Charleston Place

Frequently asked questions

Why book your business-friendly hotel in Daniel Island with Expedia?
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How can I find cheap business-friendly hotels in Daniel Island?
When work takes you on the road in Daniel Island, our "business friendly" filter will help you find the right hotel. From free WiFi to conference spaces and in-room desks, they have the amenities you need to be productive. You can also narrow your search by your preferred star rating and budget to view the most affordable accommodations.

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