Find All Upstate South Carolina Hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Find All Upstate South Carolina Hotels
We have found 2997 Upstate South Carolina Hotels
- Hilton Garden Inn Spartanburg
- Sleep Inn at Greenville Convention Cente
- Days Inn by Wyndham Clinton / Laurens I-26
- WoodSpring Suites Spartanburg - Duncan
- Swamp Rabbit Inn
- Microtel Inn by Wyndham Duncan/Spartanburg
- Quality Inn & Suites Greenville near downtown
- Holiday Inn Express & Suites Clemson by IHG
- Comfort Inn & Suites Spartanburg North
- Extended Stay America Premier Suites Greenville Woodruff Rd
- Hampton Inn Greenville/I-385 Haywood Mall
- AC Hotel by Marriott Spartanburg
- Hampton Inn Spartanburg-North I-85
- Comfort Suites Anderson-Clemson
- Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
- Hampton Inn & Suites Greenville/Spartanburg I-85, SC
- Hampton Inn Gaffney
- WoodSpring Suites Greenville Simpsonville
- Best Western Plus Greenville South
- Comfort Suites Simpsonville - Greenville
- Hampton Inn & Suites Spartanburg-I-26-Westgate Mall
- Home2 Suites by Hilton Greenville Airport
- Hampton Inn Easley
- Home2 Suites by Hilton Anderson Downtown
- Courtyard by Marriott Greenville Downtown
- Horizon Inn & Suites
- Quality Inn Spartanburg Northwest
- Hampton Inn Anderson/ Alliance Business Park
- Days Inn by Wyndham Clemson
- Hampton Inn Clemson-University Area
- Residence Inn by Marriott Greenville Downtown
- Best Western Seneca-Clemson
- Days Inn by Wyndham Greenville South/Mauldin
- HomeTowne Studios by Red Roof Greenville
- Holiday Inn Spartanburg Northwest by IHG
- Super 8 by Wyndham Anderson/Clemson Area
- stayAPT Suites Greenville Greer BMW
- Days Inn by Wyndham Seneca / Clemson Area
- Candlewood Suites Greenville by IHG
- Quality Inn Duncan - Spartanburg West
- Studio 6 Greenville, SC
- Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG
- Fairfield Inn & Suites by Marriott Anderson Clemson
- Holiday Inn Express Anderson by IHG
- Deluxe Inn
- Quality Inn Clinton - Laurens I-26
- Red Roof Inn Spartanburg – I-26
- Red Roof Inn & Suites Duncan
- Hampton Inn & Suites Clinton - I-26
- Comfort Suites Clinton near Presbyterian College
- Holiday Inn Express & Suites Greenville S- Piedmont by IHG
- Red Roof Inn Greenville
- Home2 Suites by Hilton Duncan
- USA Economy Lodge
- Doubletree By Hilton Greenville Airport
- Quality Inn Greer - Greenville
- Greenville Pelham Inn by IHG
- Days Inn by Wyndham Spartanburg
- Residence Inn by Marriott Greenville-Spartanburg Airport
- Rodeway Inn Anderson North - Clemson
- Staybridge Suites Greenville I-85 Woodruff Road by IHG
- Hampton Inn Greenville/Travelers Rest
- Quality Inn Gaffney I-85
- Residence Inn by Marriott Spartanburg
- Baymont by Wyndham Anderson Clemson
- Red Roof Inn Spartanburg - I-85
- Baymont by Wyndham Duncan/Spartanburg
- BEAUTIFUL Newly Built Retreat w/Private Marina Boat Slip at Upper Lake Keowee!!!
- Extended Stay America Select Suites - Greenville - Airport
- Motel 6 Simpsonville, SC - Greenville
- Homewood Suites by Hilton Greenville
- Fairfield By Marriott Inn & Suites Piedmont Greenville
- Budget Inn Express
- Sleep Inn Gaffney at I-85
- Hampton Inn Anderson
- Days Inn by Wyndham Simpsonville
- Americas Best Value Inn Anderson, SC
- Super 8 by Wyndham Piedmont Greenville Area
- Baymont by Wyndham Gaffney
- SUN AND SAND MOTEL
- Hotel Domestique
- Holiday Inn Express & Suites Greenville-I-85 & Woodruff Rd by IHG
- Liberty Hall Bed and Breakfast
- Residence Inn by Marriott Anderson Clemson
- Rodeway Inn Union
- Residence Inn by Marriott Spartanburg Westgate
- HomeTowne Studios by Red Roof Spartanburg - Asheville Highway
- Pettigru Place Bed & Breakfast
- Quality Inn Union US Hwy 176
- Econo Lodge Gaffney
- Charming 4-bedroom farmhouse w/ WiFi, AC in lovely Eastatoee Valley, Sunset, SC.
- Swamp Rabbit Inn Travelers Rest
- The Bleckley Inn
- Countryside Haven
- Econo Lodge Clemson - University Area
- Rodeway Inn & Suites Walhalla
Let Expedia take you to the best Hotels in Upstate South Carolina. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.