Find 5 Star Hotels in Palo Alto, CA from ￥25,707

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Palo Alto 5 Star Hotels

Our top choices for Palo Alto 5-star hotels

Poolside bar

Shashi Hotel Mountain View Palo Alto

Shashi Hotel Mountain View Palo Alto
5.0 star property
Mountain View
9.4 out of 10, Exceptional, (1,379 reviews)
"Love the place, the Broma Restaurant is amazing!!"
United States
Chance
The price is ￥23,599
￥26,005 total
includes taxes & fees
May 21 - May 22
Shashi Hotel Mountain View Palo Alto
Terrace/patio

Four Seasons Hotel Silicon Valley at East Palo Alto

Four Seasons Hotel Silicon Valley at East Palo Alto
5.0 star property
East Palo Alto
9.4 out of 10, Exceptional, (683 reviews)
"The location is uber convenient, the staff was wonderful, and the rooms are very nice. "
United States
Edward
The price is ￥61,451
￥69,867 total
includes taxes & fees
May 23 - May 24
Four Seasons Hotel Silicon Valley at East Palo Alto
Outdoor pool

Rosewood Sand Hill

Rosewood Sand Hill
5.0 star property
Menlo Park
9.4 out of 10, Exceptional, (286 reviews)
"Amazing "
United States
Maria
The price is ￥146,502
￥181,305 total
includes taxes & fees
Jun 5 - Jun 6
Rosewood Sand Hill
Breakfast, lunch, dinner served; Japanese cuisine, alfresco dining

Nobu Hotel Palo Alto

Nobu Hotel Palo Alto
5.0 star property
University South
9.2 out of 10, Wonderful, (449 reviews)
"Modern room, comfy bed and pillows. Love this place"
United States
Art
The price is ￥67,153
￥77,693 total
includes taxes & fees
May 23 - May 24
Nobu Hotel Palo Alto
Terrace/patio

Clement Palo Alto – All-Inclusive Urban Resort

Clement Palo Alto – All-Inclusive Urban Resort
5.0 star property
Palo Alto
10.0 out of 10, Exceptional, (125 reviews)
"Super helpful staff with amazing services!"
Canada
Amanda
The price is ￥106,194
￥130,295 total
includes taxes & fees
May 24 - May 25
Clement Palo Alto – All-Inclusive Urban Resort
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Palo Alto.
The Ameswell Hotel

The Ameswell Hotel

800 Moffett Blvd Mountain View CA
The price is ￥23,016 per night from May 22 to May 23
￥23,016
￥25,707 total
May 22 - May 23
includes taxes & fees
9.6/10 Exceptional! (1,268 reviews)
Still don't see what you're looking for?
See all properties in Palo Alto.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Palo Alto

Silicon Valley's heart offers visitors the chance to tour Stanford's iconic campus and stroll University Avenue's tech-inspired shops. Bike the flat, tree-lined neighborhoods where garage startups became tech giants, then hike the rolling hills of Foothills Park when you need a break.

See all hotels in Palo Alto
Aerial view of Hoover Tower at Stanford University, California, USA. The tower is a landmark, housing archives. Palo Alto, California, USA. 28 December 2024.

Top Palo Alto Hotel Reviews

Four Seasons Hotel Silicon Valley at East Palo Alto

Four Seasons Hotel Silicon Valley at East Palo Alto

10/10 Excellent
"Friendly staff and excellent amenities."
Duane 2-night trip
Posted 12 days ago
Four Seasons Hotel Silicon Valley at East Palo Alto
Clement Palo Alto – All-Inclusive Urban Resort

Clement Palo Alto – All-Inclusive Urban Resort

10/10 Excellent
"Friendly staff and a beautiful room. would visit again 10/10"
Michael 1-night trip
Posted 2 months ago
Clement Palo Alto – All-Inclusive Urban Resort

Frequently asked questions

What are the best 5-star hotels in Palo Alto?
Based on Expedia traveler reviews, Nobu Hotel Palo Alto, Clement Palo Alto – All-Inclusive Urban Resort and Four Seasons Hotel Silicon Valley at East Palo Alto are among the best 5-star hotels in Palo Alto. Providing first-rate amenities and exemplary service, you'll enjoy an indulgent and comfortable stay.
How much does it cost to stay in a 5-star hotel in Palo Alto?
The amount you pay for a 5-star hotel in Palo Alto can vary based on what time of year you travel and how long you plan to be away, among other factors. Use our price per night filter and other search tools to land the best deal on a high-end stay.

  • Search for the lowest price per night from ￥25,707

What makes a hotel 5 stars in Palo Alto?
In Palo Alto, a hotel needs to provide a specific amount of upscale features to earn a 5-star rating. These may include on-site gyms, gourmet restaurants, saunas and spas, premium bedding, luxury bathroom products and more. What also sets 5-star hotels apart is their guest-focused service. You'll enjoy things like concierge services, in-room massages and nightly turn-down services. Some may even offer special touches like welcome gifts.