Find 5 Star Hotels in Ios from ¥16,675

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Compare Ios 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Santo Pure Oia Suites & Villas

5.0 star property
9.6 out of 10, Exceptional, (458)
"Our stay was amazing! The resort was very clean and beautiful! Will come back someday.."
The price is ¥49,830
¥59,181 total
includes taxes & fees
Oct 5 - Oct 6
Santo Pure Oia Suites & Villas

NOŪS Santorini

5.0 star property
9.8 out of 10, Exceptional, (107)
"Amazing place to stay. "
The price is ¥41,985
¥50,271 total
includes taxes & fees
Sep 29 - Sep 30
NOŪS Santorini

Andronis Arcadia Hotel

5.0 star property
9.8 out of 10, Exceptional, (184)
"This is a great hotel."
The price is ¥73,779
¥86,377 total
includes taxes & fees
Oct 6 - Oct 7
Andronis Arcadia Hotel

The Majestic Hotel

5.0 star property
9.2 out of 10, Wonderful, (534)
"Super nice staff, very convenient location Close to everything "
The price is ¥37,993
¥45,737 total
includes taxes & fees
Sep 24 - Sep 25
The Majestic Hotel

Canaves Epitome - Small Luxury Hotels of the World

5.0 star property
9.8 out of 10, Exceptional, (154)
"Amazing property and staff"
The price is ¥110,288
¥127,840 total
includes taxes & fees
Sep 7 - Sep 8
Canaves Epitome - Small Luxury Hotels of the World

Santorini Princess Spa Hotel

5.0 star property
9.8 out of 10, Exceptional, (1000)
"Beautiful hotel and staff "
The price is ¥31,215
¥38,040 total
includes taxes & fees
Sep 14 - Sep 15
Santorini Princess Spa Hotel

Pegasus Spa Hotel

5.0 star property
9.2 out of 10, Wonderful, (172)
"Amazing stay and staff were so helpful and kind. 10/10 "
Pegasus Spa Hotel

Andronis Luxury Suites

5.0 star property
9.8 out of 10, Exceptional, (236)
"Amazing hotel, it has the best views that I have seen so far, we loved it! "
The price is ¥137,899
¥159,196 total
includes taxes & fees
Oct 5 - Oct 6
Andronis Luxury Suites

Aqua Luxury Suites

5.0 star property
9.2 out of 10, Wonderful, (208)
"beautiful place. highly recommend"
The price is ¥27,960
¥32,097 total
includes taxes & fees
Sep 9 - Sep 10
Aqua Luxury Suites

Desiterra Resort & Spa

5.0 star property
9.6 out of 10, Exceptional, (196)
"Amazing, best vacation! "
The price is ¥22,077
¥27,663 total
includes taxes & fees
Sep 11 - Sep 12
Desiterra Resort & Spa

Nikki Beach Resort & Spa Santorini

5.0 star property
8.6 out of 10, Excellent, (100)
"Amazing resort we had a great time. All the staff were very helpful and they made our stay fabulous. "
The price is ¥42,886
¥51,295 total
includes taxes & fees
Oct 5 - Oct 6
Nikki Beach Resort & Spa Santorini

Canaves Oia Suites - Small Luxury Hotels of the World

5.0 star property
9.8 out of 10, Exceptional, (127)
"Amazing property and fantastic service!!!"
The price is ¥114,851
¥133,021 total
includes taxes & fees
Sep 8 - Sep 9
Canaves Oia Suites - Small Luxury Hotels of the World

Canaves Ena - Small Luxury Hotels of the World

5.0 star property
10.0 out of 10, Exceptional, (201)
"Excellent location and service in a quite peaceful neighborhood."
The price is ¥107,473
¥124,641 total
includes taxes & fees
Oct 3 - Oct 4
Canaves Ena - Small Luxury Hotels of the World

Volcano View Hotel Santorini

5.0 star property
9.4 out of 10, Exceptional, (959)
"Amazing hotel, the views are incredible and the staff are friendly and helpful!"
The price is ¥42,089
¥50,389 total
includes taxes & fees
Sep 7 - Sep 8
Volcano View Hotel Santorini

Grace Hotel, Auberge Resorts Collection

5.0 star property
9.8 out of 10, Exceptional, (126)
"View is stunning and the service is exceptional. Everyone was amazingly nice, friendly and helpful. We are definitely coming back to stay again at the Grace."
The price is ¥137,991
¥162,756 total
includes taxes & fees
Oct 5 - Oct 6
Grace Hotel, Auberge Resorts Collection

De Sol Spa Hotel

5.0 star property
9.4 out of 10, Exceptional, (510)
"Amazing property, we really enjoyed it. Friendly staff, professional services."
The price is ¥31,308
¥38,145 total
includes taxes & fees
Oct 3 - Oct 4
De Sol Spa Hotel

Andronis Concept Wellness Resort

5.0 star property
9.6 out of 10, Exceptional, (107)
"I’ll stay here with spectacular. The service, the size of the room, the breakfast (included with stay and one of the best I’ve had, overlooking the caldera) the views,… Outstanding."
The price is ¥74,131
¥86,777 total
includes taxes & fees
Oct 3 - Oct 4
Andronis Concept Wellness Resort

Orama Hotel & Spa

5.0 star property
9.4 out of 10, Exceptional, (71)
"I’ve stayed at Orama twice (October 2023 and July 2025). The hotel is amazing- their clean rooms, gorgeous pools, excellent breakfast and spa! Location is about 5 mins away from center- easy walk!"
The price is ¥20,536
¥25,912 total
includes taxes & fees
Sep 28 - Sep 29
Orama Hotel & Spa

Skyfall Suites - Adults Only

5.0 star property
9.8 out of 10, Exceptional, (276)
"Quality hotel! "
The price is ¥40,068
¥48,095 total
includes taxes & fees
Oct 5 - Oct 6
Skyfall Suites - Adults Only

Katikies Santorini - The Leading Hotels Of The World

5.0 star property
9.6 out of 10, Exceptional, (359)
"Best Hotel in the best location. "
The price is ¥101,860
¥118,268 total
includes taxes & fees
Oct 4 - Oct 5
Katikies Santorini - The Leading Hotels Of The World
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Ios

The whitewashed village of Chora offers maze-like streets leading to Panagia Gremiotissa church with spectacular sunset views. Beach-hop between Mylopotas and Manganari, where crystal waters invite swimming and the beachside tavernas serve fresh seafood.

Top Ios Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Ios?
There are various pricing options for 5-star hotels in Ios on Expedia. How much you'll pay will depend on your travel dates, trip length and other factors. Compare all of the available accommodations for your desired dates and make use of our pricing and other filters to discover the ideal upscale stay.

  • Search for the lowest price per night from ¥16,675

What makes a hotel 5 stars in Ios?
Faultless guest service is the hallmark of every 5-star hotel in Ios. From the instant you arrive, staff cater to your every whim, whether recommending activities or providing in-room massage treatments. In addition, hotels have to feature upscale conveniences to qualify for a 5-star rating. These can include luxury baths, saunas or spas, pools, gastronomic kitchens and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Ios?
Use our convenient filters to find an upmarket escape in Ios where everything you need is included. After your initial search, refine your results for hotels that have a 5-star rating and are described as "All inclusive." The first thing on the agenda at these stays? Pure indulgence and relaxation.