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Top Romantic Southern Minnesota Hotels

Alexander Mansion Bed and Breakfast

274 East Broadway Winona MN

2 hours drive from Mayo Clinic

Enjoy a stay at this romantic bed & breakfast, featuring a garden and a terrace for couples to enjoy.

St James Hotel, a Historic Hotel of America

406 Main St. Red Wing MN

2 hours drive from Mayo Clinic

If you and your special someone are ready for a getaway, you're sure to love the spa and garden at this historic hotel. You'll also appreciate the luxury bedding, ...

9.2/10 Wonderful! (1,000 reviews)

Couples like: full-service spa, bar

Travelers say...

Loved the room and the restaurant! Well maintained and comfy. We had a problem with the heat in our room and they had it fixed in 10 minutes! Will definitely visit again in summer to enjoy other amenities.

Reviewed on Mar 18, 2026

AmericInn by Wyndham Austin

1700 8th St NW Austin MN

2 hours drive from Mayo Clinic

Enjoy a stay at this romantic hotel, featuring a hot tub and a lobby fireplace for couples to enjoy.

8.8/10 Excellent! (734 reviews)

there was hair in my sink the second day and then it was there the third day as well. It was a long brown hair. This lets me know that the effort to keep the room clean was minimal. In the evenings, there was activity in the lobby with kids and both those nights I could hear from my room. otherwise, ...

Reviewed on Mar 21, 2026

See all 1,198 properties in Southern Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.