The Best Hotels Closest to Mayo Civic Center in Rochester for 2026

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Our top choices for Mayo Civic Center hotels

An outdoor seating area with wooden pillars, colorful striped cushions, and potted plants.

An indoor swimming pool with wooden ceiling beams, yellow chairs, and tables along the sides.

A modern hotel room with a bed, desk, and kitchenette.

A modern restaurant with a counter, seating area, and a TV screen.

1. Home2 Suites by Hilton Rochester Mayo Clinic Area

2.9 km from Mayo Civic Center

howard

￥18,670

￥21,494 total

includes taxes & fees

Nov 12 - Nov 13

An outdoor patio area with a concrete floor, wooden fence, and string lights.

A Fairfield Inn & Suites hotel with a modern design, featuring a prominent entrance and a parking area.

A breakfast bar with a wooden counter, a coffee machine, and a refrigerator.

2. Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Kutzky Park, 2.3 km from Mayo Civic Center

Brien

￥19,057

￥21,939 total

includes taxes & fees

Nov 6 - Nov 7

A spacious living area with a modern staircase, leather sofas, and contemporary lighting.

An outdoor seating area with blue sofas and wicker chairs, a wooden table, and green ottomans on a tiled patio.

A rooftop pool area with lounge chairs and umbrellas, surrounded by a modern building with a brick facade.

A modern interior with a large dining table, sofas, and a kitchen area.

3. The Berkman

Folwell, 2 km from Mayo Civic Center

Suzette

￥32,122

￥37,351 total

includes taxes & fees

Oct 22 - Oct 23

A swimming pool with clear blue water, surrounded by lounge chairs and a view of residential buildings through large windows.

A modern hotel with a flat roof, multiple windows, and a covered outdoor seating area.

A modern reception area with a brick-patterned wall, two reception desks, a flat-screen TV, and seating arrangements including a sofa and chairs.

An outdoor patio area with wicker furniture, a central fire feature, and a stone building in the background.

4. Residence Inn by Marriott Rochester Mayo Clinic Area South

2.7 km from Mayo Civic Center

Chee

￥20,859

￥24,015 total

includes taxes & fees

Nov 13 - Nov 14

A coffee shop interior with a wooden counter, menu boards, and seating area.

A hotel room with a bed, bedside table, and a window with curtains.

An outdoor seating area with tables and chairs, a neon sign, and flower arrangements.

A hotel exterior with a 'Townplace Suites' sign, outdoor seating area, and 'OPEN' signage.

5. TownePlace Suites by Marriott Rochester Mayo Clinic Area

Kutzky Park, 0.9 km from Mayo Civic Center

Cory

￥21,649

￥24,924 total

includes taxes & fees

Nov 6 - Nov 7

A modern indoor patio with a fire feature, seating, and large windows.

A modern living room with a fireplace, large windows, and a flat-screen TV mounted on the wall.

A modern interior with a seating area, a bookshelf, and a window with a view of trees.

A reception area with a curved reception desk, wooden shelving, and a green moss wall with the text "I ♥ EVEN".

6. EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kutzky Park, 1.5 km from Mayo Civic Center

James

￥18,014

￥22,873 total

includes taxes & fees

Oct 23 - Oct 24

A modern outdoor seating area with a built-in fireplace, two wooden chairs, a table, and a sofa.

A gym with various exercise equipment, including treadmills, stationary bikes, and weight machines.

A pantry with various snacks and food items organized on shelves.

A modern kitchen with a central island, bar stools, and pendant lighting. A living area with a sofa, ottoman, and a view of the outdoors is visible.

7. Staybridge Suites Rochester - Mayo Clinic Area by IHG

Kutzky Park, 1.5 km from Mayo Civic Center

Amanda

￥18,014

￥21,056 total

includes taxes & fees

Nov 1 - Nov 2

A modern kitchen with a dark countertop, black cabinets, a microwave, and a refrigerator. There are two pendant lights above the counter.

A storage cabinet with multiple shelves containing kitchen appliances, glassware, and board games.

A person at a checkout counter in a store, with various snack items and a sign indicating a price of $1.50.

A reception area with a clock, a counter, and a nameplate.

8. Candlewood Suites Rochester Mayo Clinic Area by IHG

2.7 km from Mayo Civic Center

Kevin

￥19,120

￥22,012 total

includes taxes & fees

Oct 26 - Oct 27

A bedroom with a large bed, a TV on a dresser, and a view of the city through large windows.

A multi-story building with the sign 'Broadway Plaza' indicating a commercial or hotel property.

An indoor swimming pool with a clock on the wall, lounge chairs, and a lifeguard warning sign.

9. Broadway Plaza, Trademark Collection by Wyndham

Downtown Rochester, 0.2 km from Mayo Civic Center

Danny

￥26,729

￥30,771 total

includes taxes & fees

Nov 7 - Nov 8

A Courtyard Marriott hotel with multiple floors, a brick facade, and illuminated signage.

A conference room with a long table, multiple chairs, and decorative wall art.

A modern living room with a sofa, a round coffee table, and a side table. There are large windows with a view of the outside.

A hotel room with a sofa, armchairs, a small kitchenette, a flat-screen TV, and a large window.

10. Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

Kutzky Park, 1.9 km from Mayo Civic Center

MATTHEW

￥17,864

￥20,566 total

includes taxes & fees

Nov 6 - Nov 7

An outdoor patio with a brick floor, stone fireplace, and wooden pergola.

An indoor swimming pool with clear pool rules posted on the wall, a lifeguard chair, and a pool lift sign.

A gym with exercise equipment, a clock, and a window with blinds.

A conference room with multiple tables and chairs, ceiling fans, and artwork on the walls.

11. Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

Kutzky Park, 1.9 km from Mayo Civic Center

Lin

￥18,670

￥21,494 total

includes taxes & fees

Nov 6 - Nov 7

A self-service breakfast station with a waffle maker, coffee machines, and a variety of condiments.

A hotel room with a large bed, a desk, a chair, a television, and a window with curtains.

A compact laundry area with a washing machine, dryer, and a water fountain.

A reception area with a wooden reception desk, a red doormat, and framed awards on the wall.

12. Econo Lodge Mayo Clinic Area

3.2 km from Mayo Civic Center

Ashley

￥10,429

￥12,007 total

includes taxes & fees

Nov 8 - Nov 9

An outdoor seating area with a fire feature, blue cushioned chairs, and a modern building with large windows in the background.

A modern indoor pool area with lounge chairs and a pool.

A modern Hyatt House hotel with a prominent 'Hyatt House' sign, multiple floors, and a parking garage.

A modern bar area with seating and a counter.

13. Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester, 0.6 km from Mayo Civic Center

Elsie

￥18,804

￥21,648 total

includes taxes & fees

Oct 30 - Oct 31

A modern bathroom with a walk-in shower, grab bars, a vanity with a mirror, and a white towel hanging on the wall.

A hotel room with a bed, a desk, a chair, a TV, and a bathroom visible through an open door.

A modern lounge area with seating arrangements, a reception desk, and a patterned wall.

A pool area with a table and chairs, a lifeguard chair, and a pool lift.

14. Hampton Inn Rochester-South

3 km from Mayo Civic Center

dennis

￥17,327

￥19,948 total

includes taxes & fees

Oct 25 - Oct 26

A hotel entrance with a stone facade, a glass door, and a metal roof structure.

A hotel room with a kitchenette, a dining area with striped chairs, a sofa, a TV, and a window with curtains.

An outdoor patio area with brick walls, a large arched window, and outdoor seating.

A spa area with a hot tub, exercise equipment, and a seating area with chairs and a table.

15. Aspen Suites

1.7 km from Mayo Civic Center

Douangta

￥19,346

￥23,387 total

includes taxes & fees

Oct 22 - Oct 23

A spacious outdoor dining area with modern furniture and large windows offering views of the city.

An outdoor dining area with wooden beams, tables, and chairs.

A reception desk with a modern design, featuring a wooden panel and a wall adorned with framed botanical artwork.

A modern hotel room with a large bed, a sofa, a small table, a desk, and a wardrobe.

16. Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester, 0.3 km from Mayo Civic Center

Hernan

￥16,908

￥19,465 total

includes taxes & fees

Oct 24 - Oct 25

A room with a fireplace, two leather armchairs, a sofa, and a large window providing a view of the outdoors.

A paved garden area with two benches, a potted plant with yellow flowers, and a variety of greenery.

A hotel room with a bed, a sink, a microwave, and a window with curtains.

A long, narrow hotel corridor with a carpeted floor, light fixtures along the walls, and a ceiling with recessed lighting.

17. Brentwood Inn & Suites

Downtown Rochester, 0.7 km from Mayo Civic Center

Elaine

￥19,753

￥22,741 total

includes taxes & fees

Nov 5 - Nov 6

A hotel breakfast area with a self-serve station, including a waffle maker, toaster, and various food items.

A hotel room with a large bed, bedside tables, a mirror, and a patterned carpet.

A hotel lobby with a patterned carpet, two beige armchairs, a small table, a clock, a fire extinguisher, and a staircase.

A modern living room with a sofa, coffee table, and a TV mounted on a stone wall.

18. Quality Inn & Suites Mayo Clinic Area

2.7 km from Mayo Civic Center

Jessica

￥10,652

￥12,435 total

includes taxes & fees

Nov 13 - Nov 14

A spacious hotel lobby with multiple seating areas, including sofas and round tables, and a large dining area with yellow chairs.

A spacious lobby with a large seating area, a fireplace, and large windows providing natural light.

A reception area with two counters, a patterned wall, and a wooden floor.

A grocery store with refrigerated and frozen sections, shelves stocked with snacks, and a variety of beverages.

19. Hilton Garden Inn Rochester Downtown, MN

Downtown Rochester, 0.3 km from Mayo Civic Center

Richard

￥18,670

￥21,494 total

includes taxes & fees

Oct 24 - Oct 25

An outdoor patio area with yellow umbrellas, wicker furniture, and a sign for Centerstone Plaza Hotel.

A restaurant interior with wooden tables, chairs, and a stone wall.

A modern reception area with a wooden reception desk, glass pendant lights, and a long hallway with seating.

A garden with a water feature, rocks, and yellow umbrellas.

20. Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Historic Southwest, 1 km from Mayo Civic Center

Christine

￥18,046

￥20,775 total

includes taxes & fees

Oct 23 - Oct 24

View all properties

Compare popular hotels close to Mayo Civic Center

Property	Star rating	Guest rating
Home2 Suites by Hilton Rochester Mayo Clinic Area	9.6 Exceptional 1,003 reviews	View
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys	9.6 Exceptional 747 reviews	View
The Berkman	9.6 Exceptional 449 reviews	View
Residence Inn by Marriott Rochester Mayo Clinic Area South	9.6 Exceptional 316 reviews	View
TownePlace Suites by Marriott Rochester Mayo Clinic Area	9.6 Exceptional 569 reviews	View

Hotels recommended for families near Mayo Civic Center

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Downtown Rochester

￥16,908

￥19,465 total

includes taxes & fees

Oct 24 - Oct 25

Hyatt House Rochester/Mayo Clinic Area

Downtown Rochester

￥18,804

￥21,648 total

includes taxes & fees

Oct 30 - Oct 31

A swimming pool with a glass ceiling, a neon sign for the KAFFLER HOTEL, and a view of the city skyline at dusk.

A banquet hall with round tables, chairs, chandeliers, and a fireplace.

A bar area with a long counter, multiple bar stools, and a television mounted above the bar.

A hotel entrance with a modern design, large windows, and a sign indicating it's a Grand Hotel.

Kahler Grand Hotel

Downtown Rochester

￥23,205

￥26,714 total

includes taxes & fees

Oct 23 - Oct 24

A rooftop terrace with outdoor seating and a city skyline in the background.

A modern hotel entrance with a glass facade, a covered entrance area, and a visible 'Hilton' sign.

A modern indoor swimming pool with clear water, surrounded by lounge chairs and a seating area with a patterned wall.

A spacious lobby with modern furniture, a staircase, and large windows.

Hilton Rochester Mayo Clinic Area

Downtown Rochester

￥28,072

￥32,318 total

includes taxes & fees

Nov 7 - Nov 8

Brentwood Inn & Suites

Downtown Rochester

￥19,753

￥22,741 total

includes taxes & fees

Nov 5 - Nov 6

Broadway Plaza, Trademark Collection by Wyndham

Downtown Rochester

￥26,729

￥30,771 total

includes taxes & fees

Nov 7 - Nov 8

A poolside area with wicker chairs and potted plants, a tiled floor, and a clear view of the pool.

A restaurant with a bar area, wooden chairs, and a stone wall.

A modern building with large windows and a parking lot.

A reception area with a wooden reception desk, a clock, and a wall-mounted display.

Kahler Inn and Suites - Mayo Clinic Area

Downtown Rochester

￥19,894

￥22,904 total

includes taxes & fees

Oct 31 - Nov 1

Hilton Garden Inn Rochester Downtown, MN

Downtown Rochester

￥18,670

￥21,494 total

includes taxes & fees

Oct 24 - Oct 25

Top Mayo Civic Center Hotel Reviews

AmericInn by Wyndham Rochester Near Mayo Clinic

10/10 Excellent

"We needed a place to stay for one night, with our dog, and it was a great place to land. It was comfortable, plenty of towels and other amenities. It was so helpful to have a good-sized refrigerator as we are traveling across the country and we always bring food."