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Top Pet-friendly Southeast Minnesota Hotels

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

4353 Canal Pl SE Rochester MN

11 min drive from Mayo Clinic

Make it a pet-friendly trip and bring along your four-legged friend. Dogs are welcome (fees apply) at this suburban hotel.

7.4/10 Good! (1,066 reviews)

"We love the location of this hotel, right next to a movie theatre, Target, restaurants. The bed was comfortable, room was clean, breakfast was wonderful, staff was friendly and efficient. My only complaint is that we look forward to using the hot tubs while we are in hotels and the pool area had ..."

Reviewed on Jun 19, 2026

Med City Inn & Suites - Mayo Clinic Area

435 16th Ave Nw Rochester MN

26 min walk from Mayo Clinic

Dogs are welcome to join you (fees apply) for a pet-friendly getaway at this family-friendly, city-center motel.

8/10 Very Good! (1,002 reviews)

"Breakfast was subpar. No waffle mix, milk for cereal and pancake grill didn’t even work. Hallway was musty. Location was great for access to Mayo and a walking trail close by."

Reviewed on Jun 17, 2026

Spark by Hilton Rochester South

4165 Maine Ave SE Rochester MN

10 min drive from Mayo Clinic

Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

9.2/10 Wonderful! (507 reviews)

"The room was well priced and very clean We enjoyed our stay there even though it was only one night it was very comfortable and there were no issues"

Reviewed on Jun 18, 2026

See all 917 properties in Southeast Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.