
Southeast Missouri Pet-friendly Vacations
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Top Pet-friendly Southeast Missouri Hotels

Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
Stay at this motel in Poplar Bluff. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff and the clean rooms in our reviews. ...
8/10 Very Good! (1,004 reviews)
"The room was very clean, but definitely plan on bringing your own toiletries. There was a bar of soap, but that was it. The towels were extremely thin, but they did the job. The location is good, about 5-10 minutes away from grocery stores and fast foods. The beds were comfortable enough and the ..."
Reviewed on Jul 7, 2026

Microtel Inn & Suites by Wyndham Sainte Genevieve
21958 Hwy 32 Ste Genevieve MO
Book a stay at this business-friendly hotel in Ste Genevieve. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the ...
8.8/10 Excellent! (653 reviews)
"Good location, li item ame cities, nice roomm good for economical overnight stay"
Reviewed on Jul 12, 2026

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
1001 Veterans Blvd Festus MO
This hotel is pet-friendly, allowing dogs and cats with an additional fee. If you're going for a walk during your stay, swing by nearby Jorkerst Memorial ...
7.8/10 Good! (1,009 reviews)
"The room had mold in the air conditioner and the refund wasn’t processed like it was supposed to be."
Reviewed on Jul 12, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Things to do

Night Ghost Tour of Pythian Castle in Springfield Missouri
¥3,249
per adult
96% of travellers recommend

History Tour of Pythian Castle in Springfield Missouri
¥2,072
per adult
90% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.

