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Top Luxury vacation packages in Mesopotamia

Price found within the past 48 hours. Click for updated prices.

Sanma Hotel

Cataratas

￥57,211

per person

Jul 14 - Jul 16

found 1 day ago

Roundtrip flight included

São Paulo (CGH) to Iguassu Falls (IGU)

9.6/10 Exceptional! (863 reviews)

This is a beautiful place to stay! It has a pool, jacuzzi and sauna. There is a children's play area and a shaded walking path. The buffet style breakfast served every day is absolutely delicious. We were given a glass of champagne upon checking in as a welcome drink. Laundry service is available same day for a small extra cost. My husband and I loved every moment of our stay! We only wish we could have stayed a day or 2 longer. The resort is a 15 minute walk from the entrance to Igassu Falls.

Reviewed on May 11, 2026

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

￥156,329

per person

Jul 14 - Jul 16

found 1 day ago

Roundtrip flight included

São Paulo (CGH) to Iguassu Falls (IGU)

9.8/10 Exceptional! (1,007 reviews)

This is the most enjoyable experience we have ever had in a hotel. The location by the Iguaçu Falls and the property, service and good were impeccable

Reviewed on May 1, 2026

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5* Luxury vacations in Mesopotamia

Price found within the past 48 hours. Click for updated prices.

Sanma Hotel

Cataratas

￥57,211

per person

Jul 14 - Jul 16

found 1 day ago

Roundtrip flight included

São Paulo (CGH) to Iguassu Falls (IGU)

9.6/10 Exceptional! (863 reviews)

This is a beautiful place to stay! It has a pool, jacuzzi and sauna. There is a children's play area and a shaded walking path. The buffet style breakfast served every day is absolutely delicious. We were given a glass of champagne upon checking in as a welcome drink. Laundry service is available same day for a small extra cost. My husband and I loved every moment of our stay! We only wish we could have stayed a day or 2 longer. The resort is a 15 minute walk from the entrance to Igassu Falls.

Reviewed on May 11, 2026

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

￥156,329

per person

Jul 14 - Jul 16

found 1 day ago

Roundtrip flight included

São Paulo (CGH) to Iguassu Falls (IGU)

9.8/10 Exceptional! (1,007 reviews)

This is the most enjoyable experience we have ever had in a hotel. The location by the Iguaçu Falls and the property, service and good were impeccable

Reviewed on May 1, 2026

Don't see what you're looking for?

See all available trips from São Paulo to Mesopotamia

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Top Luxury Mesopotamia Hotels

Hotel das Cataratas, A Belmond Hotel, Iguassu Falls

Rodovia Br 469 Km 32 Foz do Iguaçu PR

17 hours drive from Termas de Federacion

Treat yourself to a luxury stay at Hotel das Cataratas, A Belmond Hotel, Iguassu Falls, where you can enjoy amenities like 24-hour room service, free stocked ...

9.8/10 Exceptional! (1,019 reviews)

This is the most enjoyable experience we have ever had in a hotel. The location by the Iguaçu Falls and the property, service and good were impeccable

Reviewed on May 1, 2026

Iguazu Grand Resort Spa & Casino

Route 12 Km 1640 Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

Pamper yourself with a luxury stay at Iguazu Grand Resort Spa & Casino, where you can enjoy amenities like Champagne service, massage services, and more. The ...

9/10 Wonderful! (655 reviews)

Relaxing, safe, very nice staff.

Reviewed on May 7, 2026

Gran Melia Iguazú

Parque Nacional Iguazu Puerto Iguazú Misiones

17 hours drive from Termas de Federacion

Go for a luxurious stay at Gran Melia Iguazú, where you can enjoy amenities like massage services, Egyptian cotton sheets, and more. Deluxe amenities at this ...

9.4/10 Exceptional! (1,002 reviews)

The whole experience was perfect. The first things you see when entering the hotel are the waterfalls - such an amazing view. The staff was truly lovely as well. Being able to get up in the morning to be the first in the park was such a pleasure. Highly recommend this hotel.

Reviewed on May 10, 2026

See all 519 properties in Mesopotamia

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.