Photo by Southernmost Illinois Tourism Bureau

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Top Luxury Southwest Illinois Hotels

Super 8 by Wyndham Troy IL/St. Louis Area

910 Edwardsville Rd Troy IL

3 hours drive from Southern Illinois University

Indulge yourself with classy lodging with a stay at Super 8 by Wyndham Troy IL/St. Louis Area, where you'll enjoy amenities like premium channels and more.

8.2/10 Very Good! (1,007 reviews)

"Clean room, Courteous staff. Great amenities"

Reviewed on Nov 2, 2026

Super 8 by Wyndham Mt. Vernon IL

401 S 44th St Mount Vernon IL

2 hours drive from Southern Illinois University

Spoil yourself with upscale accommodations at Super 8 by Wyndham Mt. Vernon IL, where you'll enjoy amenities like premium channels and more.

7.8/10 Good! (1,001 reviews)

"There are multiple stores and restaurants nearby"

Reviewed on Nov 2, 2026

Super 8 by Wyndham Carbondale

1180 E Main St Carbondale IL

5 min drive from Southern Illinois University

Treat yourself to classy lodging with a stay at Super 8 by Wyndham Carbondale, where you'll enjoy amenities like premium channels and more.

See all 796 properties in Southwest Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.