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Top Luxury vacation packages in Upstate South Carolina

Price found within the past 48 hours. Click for updated prices.

Greenville Marriott

￥211,970

per person

Feb 26 - Mar 5

found 1 day ago

Roundtrip non-stop flight included

Tokyo (HND) to Greenville (GSP)

8.6/10 Excellent! (603 reviews)

Front desk was so pleasant and helpful! Rooms were clean. Housekeeping was great too!

Reviewed on Dec 7, 2025

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Top Luxury Upstate South Carolina Hotels

The Westin Poinsett Greenville

120 South Main St Greenville SC

1 hour drive from Clemson University

Go for a luxurious stay at The Westin Poinsett Greenville, where you can enjoy amenities like 24-hour room service, pillowtop beds, and more. Notable amenities ...

9.2/10 Wonderful! (1,000 reviews)

Awesome place

Reviewed on Dec 5, 2025

Hyatt Regency Greenville

220 N Main St Greenville SC

1 hour drive from Clemson University

Stay in the lap of luxury at Hyatt Regency Greenville, where you can enjoy amenities like pillowtop beds, designer toiletries, and more. Deluxe amenities at ...

8.6/10 Excellent! (1,010 reviews)

The room was very clean, but the curtains did have what looked like brown finger print stains and the comforter had a small yellow staib. I spoke with one housekeeper that was kind, the man I spoke with at the desk was OK. I was accommodated with my early check in, but I did not get the higher floor ...

Reviewed on Dec 14, 2025

Sleep Inn at Greenville Convention Cente

231 N Pleasantburg Dr Greenville SC

1 hour drive from Clemson University

Indulge in a luxury vacation at Sleep Inn at Greenville Convention Cente. Notable amenities at this hotel include a fitness center and an area shuttle.

7.8/10 Good! (1,000 reviews)

Everything was ok , had a deposit to pay inwhich all that should have been up front but other than that , cool

Reviewed on Dec 6, 2025

See all 2,910 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.