Southeast Minnesota Pet-friendly Vacations

Book a Pet-friendly Hotel + Flight or Car together to unlock savings

Photo by Sara Crotts

Top Pet-friendly Southeast Minnesota Hotels

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3 out of 5
4353 Canal Pl SE Rochester MN
  • 11 min drive from Mayo Clinic
Make it a pet-friendly trip and bring along your four-legged friend. Dogs are welcome (fees apply) at this suburban hotel.
7.2/10 Good! (1,027 reviews)
Great value for the price.

Reviewed on Dec 1, 2025

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S
Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

2.5 out of 5
435 16th Ave Nw Rochester MN
  • 26 min walk from Mayo Clinic
Dogs are welcome to join you (fees apply) for a pet-friendly getaway at this family-friendly, city-center motel.
7.8/10 Good! (1,022 reviews)
Pleasant stay, great location

Reviewed on Dec 1, 2025

Med City Inn & Suites - Mayo Clinic Area
Spark by Hilton Rochester South

Spark by Hilton Rochester South

3 out of 5
4165 Maine Ave SE Rochester MN
  • 10 min drive from Mayo Clinic
Book a stay at this business-friendly hotel in Rochester. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (301 reviews)
Not quite what I expected with the excellent rating it had. Once again there were long hair strands on the counter, in the tub and on the floor. There is no in room coffee! When you come in to register you are greeted with a sign and a phone that says "dial zero for attendant", really makes you feel ...

Reviewed on Dec 6, 2025

Spark by Hilton Rochester South
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.