Photo by Southernmost Illinois Tourism Bureau

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Top Pet-friendly Southern Illinois Hotels

La Quinta Inn & Suites by Wyndham Effingham

1103 Avenue Of Mid America Effingham IL

4 hours drive from Shawnee National Forest

This pet-friendly hotel welcomes dogs and cats (fees apply).

9.2/10 Wonderful! (1,007 reviews)

Clean rooms amazing housekeeping staff

Reviewed on May 11, 2026

La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis

136 Regency Park O'Fallon IL

4 hours drive from Shawnee National Forest

This pet-friendly hotel welcomes dogs and cats (fees apply).

5.8/10 (1,001 reviews)

The room was comfotable and clean slept well but the coffe maker didnt work and the shampoo dispenser was empty

Reviewed on May 11, 2026

Red Roof Inn St Louis - Troy, IL

2030 Formosa Road Troy IL

4 hours drive from Shawnee National Forest

Make it a pet-friendly trip and bring along your four-legged friend. Dogs and cats are welcome (fees apply) at this city-center hotel.

7.8/10 Good! (1,001 reviews)

Microwave was extremely dirty everything in the room had dust shower curtain was dirty fridge had tape holding the shelves up in it toilet took forever to flush bathroom amenities where used and some didn't have lids on them like the shower soap but the dust was the main thing it looked like the ...

Reviewed on Apr 30, 2026

See all 1,165 properties in Southern Illinois

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.