Southern Illinois Pet-friendly Vacations
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Photo by Southernmost Illinois Tourism Bureau
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Top Pet-friendly Southern Illinois Hotels
La Quinta Inn & Suites by Wyndham Effingham
1103 Avenue Of Mid America, Effingham, IL
This pet-friendly hotel welcomes dogs and cats (fees apply).
9.2/10 Wonderful! (1,010 reviews)
"We had stayed at this hotel over a year ago when in the state. Was very pleased with the cleanliness of the hotel then. Coming back to the area we decided to stay here again. Was not disappointed. Very very nice, our room was perfect! Was not happy pets were allowed however you would not know it! ..."
Reviewed on Sep 25, 2025
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
136 Regency Park, O'Fallon, IL
This pet-friendly hotel welcomes dogs and cats (fees apply).
6/10 (1,006 reviews)
"Room was clean, staff friendly and helpful."
Reviewed on Sep 25, 2025
Red Roof Inn St Louis - Troy, IL
2030 Formosa Road, Troy, IL
Make it a pet-friendly trip and bring along your four-legged friend. Dogs and cats are welcome (fees apply) at this city-center hotel.
7.6/10 Good! (1,003 reviews)
"Great Customer Service. Close (walking distance) from a few dining options. Allowed pets. Had guest laundry services."
Reviewed on Sep 13, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
