Southwest Illinois Pet-friendly Vacations
Book a Pet-friendly Hotel + Flight or Car together to unlock savings
Photo by Southernmost Illinois Tourism Bureau
- Plan, book, travel with confidence
Better together
Save up to ￥45,448 when you book a flight and hotel together*
Find the right fit
With over 300,000 hotels worldwide, it's easy to create a perfect package
Rest easy
Plan, book, and manage your trip all in one place
Top Pet-friendly Southwest Illinois Hotels
La Quinta Inn & Suites by Wyndham O'Fallon, IL - St. Louis
136 Regency Park, O'Fallon, IL
This pet-friendly hotel welcomes dogs and cats (fees apply).
6/10 (1,006 reviews)
"Room was clean, staff friendly and helpful."
Reviewed on Sep 25, 2025
Red Roof Inn St Louis - Troy, IL
2030 Formosa Road, Troy, IL
Make it a pet-friendly trip and bring along your four-legged friend. Dogs and cats are welcome (fees apply) at this city-center hotel.
7.6/10 Good! (1,003 reviews)
"Great Customer Service. Close (walking distance) from a few dining options. Allowed pets. Had guest laundry services."
Reviewed on Sep 13, 2025
La Quinta Inn & Suites by Wyndham Collinsville - St. Louis
6 Gateway Dr, Collinsville, IL
Make it a pet-friendly trip and bring along your four-legged friend. Dogs and cats are welcome (fees apply) at this city-center hotel.
7.2/10 Good! (1,011 reviews)
"Room was clean, price was great. Only complaint was set up in bathroom: toilet is too close to sink vanity, and shower set up doesn't allow you to turn on water from outside shower. Otherwise, everything was wonderful: bed, pillows, size of room, towels."
Reviewed on Sep 24, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
