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Top Pet-friendly Upstate South Carolina Hotels

Aloft by Marriott Greenville Downtown

5 North Laurens Street Greenville SC

1 hour drive from Clemson University

Four-legged friends will enjoy free stays and pet-approved amenities, like food and water bowls, at this city-center hotel. If you need a walk during your visit, ...

9.2/10 Wonderful! (1,005 reviews)

"This was a great stay for our first time in Greenville - I highly recommend!"

Reviewed on May 24, 2026

La Quinta by Wyndham Haywood Mall-Near Greenville Downtown

65 W Orchard Park Dr Greenville SC

1 hour drive from Clemson University

This hotel is pet-friendly, allowing dogs and cats with an additional fee. If you're going for a walk during your stay, swing by nearby Butler Springs Park.

7.4/10 Good! (1,134 reviews)

"Friendly, piece quit sleeping was great"

Reviewed on May 24, 2026

Best Western Greenville Airport Inn

5009 Pelham Road Greenville SC

2 hours drive from Clemson University

Dogs and cats will approve of the pet-friendly amenities, such as a dog park, during their stay at this hotel (fees apply for pets).

7.8/10 Good! (1,004 reviews)

"Beds were pretty comfortable. A/C was nice but noisy. The price was good. Next to a waffle house."

Reviewed on May 22, 2026

See all 2,997 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.