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Top Pet-friendly Upstate South Carolina Hotels

Aloft Greenville Downtown

5 North Laurens Street Greenville SC

1 hour drive from Clemson University

Four-legged friends will enjoy free stays and pet-approved amenities, like food and water bowls, at this city-center hotel. If you need a walk during your visit, ...

9.2/10 Wonderful! (1,001 reviews)

Perfect location

Reviewed on Mar 2, 2026

La Quinta by Wyndham Haywood Mall-Near Greenville Downtown

65 W Orchard Park Dr Greenville SC

1 hour drive from Clemson University

This hotel is pet-friendly, allowing dogs and cats with an additional fee. If you're going for a walk during your stay, swing by nearby Butler Springs Park.

7.4/10 Good! (1,119 reviews)

We did book through an online alternate site vs directly so dinner make a difference? we were given a handicapped room which we didn’t request. But no problem with that- had nice feature such as door peek hole at right level, large bathroom. But room condition was just ok. Toilet bowl didn’t leak ...

Reviewed on Mar 8, 2026

Best Western Greenville Airport Inn

5009 Pelham Road Greenville SC

2 hours drive from Clemson University

Dogs and cats will approve of the pet-friendly amenities, such as a dog park, during their stay at this hotel (fees apply for pets).

7.8/10 Good! (1,000 reviews)

N/A

Reviewed on Mar 9, 2026

See all 2,946 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.