
Sicily Luxury Vacations
Book a Luxury Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to ¥109,000 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top Luxury Sicily Hotels

San Domenico Palace, Taormina, A Four Seasons Hotel
PIAZZA SAN DOMENICO, 5 Taormina ME
The price is ¥418,115 per night from May 4 to May 5
¥418,115
¥461,764 total
May 4 - May 5
includes taxes & fees
Choose luxury at San Domenico Palace, Taormina, A Four Seasons Hotel, where you can enjoy amenities like Champagne service, massage services, and more. Deluxe ...
9.4/10 Exceptional! (296 reviews)
This is the most beautiful hotel I have stayed at in the world. I look forward to coming back again as soon as I can. The setting is breathtaking, the renovated content is beautiful and the staff are lovely.
Reviewed on Apr 24, 2026

Grand Hotel Des Ètrangers - The Leading Hotels of the World
Passeggio Adorno 10/12 Syracuse SR
The price is ¥85,624 per night from May 26 to May 27
¥85,624
¥96,024 total
May 26 - May 27
includes taxes & fees
Grand Hotel Des Ètrangers - The Leading Hotels of the World delivers luxe lodging where you'll enjoy designer toiletries and more. The spa, outdoor pool, and ...
9.6/10 Exceptional! (76 reviews)
Breakfast menu was fresh, delicious and varied.Eggs any style are made to order. Staff very attentive. Location of hotel is perfect for overlooking the bay and at night for cocktails at the rooftop lounge and restaurant. Hotel is well located for visiting Ortygia with many nearby restaurants and ...
Reviewed on Apr 23, 2026

Grand Hotel Ortigia Siracusa
Viale Mazzini, 12 Syracuse SR
The price is ¥49,631 per night from May 16 to May 17
¥49,631
¥56,466 total
May 16 - May 17
includes taxes & fees
Grand Hotel Ortigia Siracusa is one of the Syracuse luxury 5-star beach properties where you can treat yourself to Champagne service, plush bedding, and more. ...
9/10 Wonderful! (588 reviews)
The hotel is beautiful and the first night I was there I was in a really cool room with a loft. I left for a week and then came back and stayed another night. This time the room was underneath the restaurant and was super loud until well after 11 PM. But overall, it’s a lovely property and very well ...
Reviewed on Apr 11, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
