Upstate South Carolina Beach Vacations 2026

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Top Beach Upstate South Carolina Hotels

😎Anchors Down Lakeside Retreat 15 min to Clemson🏈 Dock, Padle boat, Kayaks

Seneca SC

21 min drive from Clemson University

Lounge by the shoreline in Seneca, as you'll be a short walk from the beach when booking a getaway at this vacation home. Beach towels and sun loungers are just ...

10/10 Exceptional! (245 reviews)

Travelers like: on the beach, sun loungers, beach towels, pool

Travelers say...

"Very well- equipped and appointed accommodations. The hosts went above and beyond to make sure our stay was lovely and added extra touches unique and special to our stay. The yard was lovely and in bloom. We spent most of our time on the wonderful screened in porch or out on the dock enjoying the ..."

Reviewed on Aug 7, 2026

Quality Inn Clinton - Laurens I-26

105 Trade St Clinton SC

3 hours drive from Clemson University

Book a stay at this business-friendly hotel in Clinton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

7.4/10 Good! (568 reviews)

"The room is okay for one night"

Reviewed on Aug 21, 2026

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

801 Spartan Blvd Spartanburg SC

2 hours drive from Clemson University

Stay at this hotel in Spartanburg. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ...

8.6/10 Excellent! (1,002 reviews)

"Great stay! Close to restaurants, comfortable bed."

Reviewed on Aug 23, 2026

See all 3,052 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.