Downtown Clayton, MO

St. Louis

Downtown Clayton

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Things to do


Downtown Clayton Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is ¥15,928 per night from Apr 19 to Apr 20
¥15,928
¥18,594 total
Apr 19 - Apr 20
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,145 reviews)
The rooms are clean. Breakfast buffet is veryvgood. Staff are very friendly. I will book again if i'm back in the area.

Reviewed on Apr 6, 2026

Clayton Plaza Hotel & Extended Stay
The Ritz-Carlton, St. Louis

The Ritz-Carlton, St. Louis

5 out of 5
100 Carondelet Plaza St. Louis MO
The price is ¥79,675 per night from Apr 12 to Apr 13
¥79,675
¥93,011 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this luxury hotel in St. Louis. Enjoy 2 restaurants, 3 bars/lounges, and breakfast (surcharge). Our guests praise the helpful staff and the room ...
9.2/10 Wonderful! (562 reviews)
Excellent and the room service food was AMAZING. We are making this hotel our go to everytime we visit st. Louis

Reviewed on Mar 28, 2026

The Ritz-Carlton, St. Louis
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
The price is ¥26,984 per night from Apr 19 to Apr 20
¥26,984
¥31,769 total
Apr 19 - Apr 20
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.8/10 Excellent! (707 reviews)
Parking went up to $35 night. Small, tight hotel Parking garage, but it was secure. Ice machine in floor Wasn’t working, bar area was nice.

Reviewed on Apr 3, 2026

Le Méridien St. Louis Clayton
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

3 out of 5
227 South Central Ave St. Louis MO
The price is ¥25,388 per night from Apr 12 to Apr 13
¥25,388
¥29,637 total
Apr 12 - Apr 13
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
9/10 Wonderful! (273 reviews)
Great staff!

Reviewed on Apr 3, 2026

AC Hotel St. Louis Clayton
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
The price is ¥19,957 per night from Apr 13 to Apr 14
¥19,957
¥23,336 total
Apr 13 - Apr 14
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the restaurant ...
8.8/10 Excellent! (1,928 reviews)
Extremely rude employees at the breakfast was leaving the gravy open for my daughter to get some shecliterally shut it while she was grabbing the laddle Housekeeper doesnt speak english and failed to clean our room and provide extra towels as requested

Reviewed on Apr 6, 2026

Pear Tree Inn St. Louis Near Union Station
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
The price is ¥28,739 per night from Apr 8 to Apr 9
¥28,739
¥33,604 total
Apr 8 - Apr 9
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
9.4/10 Exceptional! (3,359 reviews)
Perfection in every way. Breakfast was amazing. The soda machine was a game changer!! Breakfast tables were always clean (cleaned in between families). From the moment I walked in, the staff was friendly, welcoming, and helpful. Our hotel room was clean. The pool and hot tub space was amazing. My ...

Reviewed on Apr 5, 2026

Drury Plaza Hotel St. Louis at the Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Downtown Clayton

St. Louis Missouri

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

Clayton
University City

University City

Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like Museum of Transportation and Heman Park Tennis Center are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.

University City
View of St. Louis and the historic Gateway Arch in Missouri, from across the Mississippi River in Malcolm W. Martin Memorial Park, Illinois

Ladue

The restaurants and churches are a few reasons travelers visit Ladue. Though there aren't many top sights in the neighborhood, you can visit Saint Louis Galleria Mall and St. Louis Zoo, a few notable attractions nearby.

Ladue
The bandstand located in Forest Park, St. Louis, Missouri.

Dogtown

If you're looking for some top things to see and do in Dogtown and surrounding area, you can visit St. Louis Zoo and St. Louis Art Museum.

Dogtown
Visitor Center in Forest Park in St. Louis

The Hill

If you're looking for some top things to see and do in The Hill and surrounding area, you can visit St. Louis Zoo and St. Louis Science Center.

The Hill
Central West End

Central West End

4.5/5(456 area reviews)

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Central West End


Downtown Clayton, MO