Downtown Clayton, MO

St. Louis

A bronze bell with an eagle atop, surrounded by greenery and a street scene in the background.

Things to do

Pappy's Smokehouse

Private Tour of St. Louis's Iconic BBQ Joints & Breweries

￥22,253
per adult
Private Tour of St. Louis's Iconic BBQ Joints & Breweries
The Gateway Arch National Park & Museum

StL's Signature "Sights and Bites" - Private Tour in St. Louis

￥27,454
per adult
StL's Signature "Sights and Bites" - Private Tour in St. Louis
St. Louis: Gateway Ghouls and Hauntings Walking Tour

St. Louis Ghost Tour: Sinister Sins & Shadows

￥3,765
per adult
100% of travellers recommend
St. Louis Ghost Tour: Sinister Sins & Shadows
St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour

St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour

￥2,665
per traveler
St. Louis & Gateway Arch NP Self Guided Walk & Drive Audio Tour
Lemp Haunted Neighborhood Walking Tour

Lemp Haunted Neighborhood Walking Tour

￥3,922
per adult
84% of travellers recommend
Lemp Haunted Neighborhood Walking Tour
Self Guided Walking & Driving Audio Tour St. Louis

Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP

￥2,352
per traveler
Self Guided Walk & Drive Audio Tour St. Louis & Gateway Arch NP
See all activities in St. Louis

Downtown Clayton Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is ￥14,539 per night from Nov 8 to Nov 9
￥14,539
￥16,973 total
Nov 8 - Nov 9
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (3,499 reviews)
"Breakfast is awesome and definitely worth it. However, this hotel is very outdated, very chopped up floor plan and would definitely be elevated by a remodel."

Reviewed on Oct 22, 2026

Clayton Plaza Hotel & Extended Stay
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
The price is ￥24,065 per night from Nov 1 to Nov 2
￥24,065
￥28,334 total
Nov 1 - Nov 2
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.8/10 Excellent! (794 reviews)
"Hairs in the shower and sucks that you have to pay for WiFi"

Reviewed on Oct 20, 2026

Le Méridien St. Louis Clayton
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

2 out of 5
227 South Central Ave St. Louis MO
The price is ￥20,308 per night from Oct 25 to Oct 26
￥20,308
￥23,707 total
Oct 25 - Oct 26
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
AC Hotel St. Louis Clayton
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
The price is ￥14,234 per night from Oct 27 to Oct 28
￥14,234
￥16,900 total
Oct 27 - Oct 28
includes taxes & fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (3,309 reviews)
"Convenience to the airport and shuttle to airport"

Reviewed on Oct 22, 2026

Pear Tree Inn St. Louis Airport
Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
The price is ￥21,351 per night from Oct 27 to Oct 28
￥21,351
￥24,966 total
Oct 27 - Oct 28
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and 2 hot tubs. Our guests praise the breakfast and the pool in our ...
Drury Plaza Hotel St. Louis at the Arch
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
Fully refundable
The price is ￥21,210 per night from Oct 30 to Oct 31
￥21,210
￥25,013 total
Oct 30 - Oct 31
includes taxes & fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
Hyatt Regency St. Louis at The Arch
See all 1,943 properties in Downtown Clayton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown Clayton

Find the best Downtown Clayton areas and neighborhoods for the activities you enjoy most.
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Ample dining options, fascinating museums, and great live music are just a few top things to explore in Downtown St. Louis. A visit to Old Courthouse or Gateway Arch National Park might round out your trip, and you can jump aboard the metro at 8th and Pine Station or Stadium Station to get around town.

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Visitors often come to Clayton for its abundant dining options, but many stay to explore sights like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. Getting around the area on the metro is easy if you catch a ride at Clayton Station.

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its abundant dining options, and you can plan a trip to Historic Main Street and Missouri River while you're in town.

A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

The ample dining options and lush forests are just a few popular features of the neighborhood. Make a stop by World Chess Hall of Fame or Blue Strawberry while you're visiting, and jump aboard the metro at Central West End Station to get around town.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Creve Coeur is known for its abundant dining options, and you can plan a trip to Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Downtown Clayton, MO