Search Guest Houses in South Carolina Midlands

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks
In one month
In two months

Guest Houses in South Carolina Midlands

Our top choices for South Carolina Midlands guest houses

The Queen Anne Inn

2.5 star property
8.0 out of 10, Very Good, (87)
"The property was close to theater venues and restaurant options. I felt safe in the neighborhood. The hosts were knowledgeable and accommodating. I will stay again "
The price is ¥22,041
¥26,119 total
includes taxes & fees
Aug 26 - Aug 27
The Queen Anne Inn

1 bedroom, 1 bathroom home that sleeps 3

10.0 out of 10, Exceptional, (5)
"We loved this cottage and the location! The host was very responsive and helpful when we had questions. This location is perfectly located—great food and walking on the beautiful campus were so close."
1 bedroom, 1 bathroom home that sleeps 3

Burch's Carriage House

9.8 out of 10, Exceptional, (30)
"This pet friendly accomodation was perfect for my trip to South Carolina! Will definitely be booking this again on my next trip to the area."
The price is ¥12,490
¥22,423 total
includes taxes & fees
Aug 27 - Aug 28
Burch's Carriage House

Casita - COLA & Hot Tub

9.6 out of 10, Exceptional, (5)
"Nice and quiet spot to relax and unwind."
The price is ¥16,972
¥29,903 total
includes taxes & fees
Aug 28 - Aug 29
Casita - COLA & Hot Tub

Amazing Studio Guesthouse, in beautiful Columbia Lake community suburb.

10.0 out of 10, Exceptional, (9)
"I planned a quick mother daughter trip to celebrate my daughter’s upcoming birthday and chose this rental last minute. We were delighted the moment we walked in the door to the jazz music lightly playing in the background. The guest house was tastefully decorated and complete with so many personal touches you couldn’t help but feel welcomed. We loved our stay and would return in a heartbeat!"
The price is ¥20,895
¥26,693 total
includes taxes & fees
Aug 26 - Aug 27
Amazing Studio Guesthouse, in beautiful Columbia Lake community suburb.

Adorable 2-br guest suite minutes from SouthPark/Uptown

9.4 out of 10, Exceptional, (12)
"Our friends stayed here for my husband’s birthday party. It was a PERFECT location! Everything was clean and the decor was so cute. They said the bed was very comfortable and the communication with Olga was fantastic. Highly recommmend!"
The price is ¥17,486
¥42,507 total
includes taxes & fees
Aug 28 - Aug 29
Adorable 2-br guest suite minutes from SouthPark/Uptown

1 bedroom, 1 bathroom home that sleeps 3

9.0 out of 10, Wonderful, (4)
"Clean, comfortable, and convenient. Checked all the boxes."
The price is ¥9,551
¥39,901 total
includes taxes & fees
Aug 26 - Aug 27
1 bedroom, 1 bathroom home that sleeps 3

NEW! Designer Remodel w King Bed, Fast WiFi

9.4 out of 10, Exceptional, (20)
"The place was beautiful will be returning for family gatherings "
The price is ¥26,302
¥62,830 total
includes taxes & fees
Sep 3 - Sep 4
NEW! Designer Remodel w King Bed, Fast WiFi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top South Carolina Midlands Hotel Reviews