The Best Resorts & Hotels with Spas in Sioux Falls, SD from ￥17,114 in 2026

A waterfall, a brick building, and a park with pathways and lampposts.

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Check availability on Sioux Falls Resorts & Hotels with Spas

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Our top choices for Sioux Falls hotels with a spa

1. TownePlace Suites by Marriott Sioux Falls

Mall District

Welcoming hotel offers daily spa service, indoor hot tub, and 24-hour fitness center for relaxation.

￥15,315

￥17,114 total

includes taxes & fees

Oct 11 - Oct 12

2. Grand Falls Casino & Golf Resort

Larchwood

Rejuvenate in a luxury spa sanctuary with 12 treatment rooms and a serene golf course setting for total relaxation.

￥22,122

￥24,776 total

includes taxes & fees

Sep 28 - Sep 29

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Choose what matters most at spa hotels in Sioux Falls

Pool

Breakfast included

Hot tub

5 stars

4 stars

Top Sioux Falls Hotel Reviews

Clarion Pointe Sioux Falls Airport

8/10 Good

"The property was average maintained, and the staff was not pleasant. The housekeeper knocked on the door rather loud to let me know that check out was 11am when checkout was 12PM. Very disappointed with the overall service and maintenance of the hotel."

Comfort Inn & Suites Avera Southwest

8/10 Good

"Room was nice, breakfast was good. Great stay!!!"

Frequently asked questions

Looking for a spa hotel in Sioux Falls?

Forget the stress of everyday life and book yourself a lush spa hotel. Travelers highly recommend Sioux Falls for its array of shops and gourmet restaurants—your day tour starts here. Enjoy the art galleries and waterfalls during your vacation. Hotels with spas are the perfect way to take a break from your routine and add a layer of luxury to your weekend away.

What is the best spa hotel in Sioux Falls?

TownePlace Suites by Marriott Sioux Falls is a top spa hotel featuring a 24-hour fitness center and an indoor pool. Enjoy the hot tub at the on-site spa.

How many spa hotels will I find in Sioux Falls?

Among Expedia's 403 accommodation options in Sioux Falls, there is 1 spa hotel.

What's there to see and do in Sioux Falls?

Enjoy Sioux Falls with a stop at Washington Pavilion of Arts and Science, Sioux Falls Arena, and Denny Sanford Premier Center. If you have some spare time during your trip, you might want to check out Great Plains Zoo and Sioux Empire Fairgrounds.

What is a Sioux Falls spa hotel?

Spa hotels in Sioux Falls provide lodging and have an on-site spa offering services such as couples massages as well as beauty treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.