Centro Histórico
Santa Cruz
Visit Centro Histórico
Stay near popular Centro Histórico attractions
Things to do
Santa Cruz: Wildlife Sanctuary and Preservation Park Tour
￥13,335
per adult
Samaipata Fort Tour: Ancient Ruins in 1 Full Day
￥46,907
per adult
4D/3N Expedition: Che Guevara Route - Disconnect from the World
￥125,347
per adult
Centro Histórico Hotel Deals
Lido Hotel
Calle 21 de Mayo 527 Santa Cruz
The price is ￥3,619 per night from Nov 2 to Nov 3
￥3,619
￥3,619 total
Nov 2 - Nov 3
Stay at this hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Arenal Park and Ethno-folkloric Museum are located ...
Hotel Las Américas
Calle 21 de Mayo esq, Seoane N 356 Santa Cruz Santa Cruz Department
Fully refundableReserve now, pay when you stay
The price is ￥3,681 per night from Oct 26 to Oct 27
￥3,681
￥3,681 total
Oct 26 - Oct 27
Stay at this hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and a 24-hour front desk. Popular attractions La Recova Artisan Walk and Guarani Nandereko ...
8/10 Very Good! (35 reviews)
"Great place for the price. Only issue I had was the music blaring one of two nights across the street - all night, from 9pm to 6am. Not the hotels fault; but frustrating. Would stay again though"
Reviewed on Oct 22, 2026
Cosmopolitano Hotel Boutique
Pari, 70 Santa Cruz
The price is ￥8,281 per night from Nov 16 to Nov 17
￥8,281
￥8,281 total
Nov 16 - Nov 17
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Centro Cultural Feliciana Rodríguez ...
9.2/10 Wonderful! (138 reviews)
"Good location. I had tour the next day, they helped me prepare my breakfast takeaway. Nice"
Reviewed on Oct 18, 2026
Senses Boutique Hotel
Calle 24 de Septiembre, Esq. Sucre No 5 Santa Cruz
Book a stay at this family-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free valet parking. Popular attractions Franco Aleman Cultural ...
Hotel Pascana centro
sucre 0 Santa Cruz Département de Santa Cruz
The price is ￥13,542 per night from Nov 2 to Nov 3
￥13,542
￥13,542 total
Nov 2 - Nov 3
Book a stay at this business-friendly hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Franco Aleman Cultural Center ...
8/10 Very Good! (1 review)
"Estavamos em 5 pessoas ...o quarto duplo nao temos oq reclamar, quarto enorme , banheiro enorme, chuveiro bom., secador maravilhoso... ja que ficou no quarto triplo , era menosr, banheiro pequeno , chuveiro nao funcionou , o cartão magnético nao funcionou.."
Reviewed on Oct 21, 2026
Gran Hotel Santa Cruz
# 247 Rene Moreno Santa Cruz Departamento de Santa Cruz
The price is ￥9,940 per night from Oct 27 to Oct 28
￥9,940
￥9,940 total
Oct 27 - Oct 28
Book a stay at this luxury hotel in Santa Cruz. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Centro Cultural Feliciana Rodríguez and ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Centro Histórico
Find the best Centro Histórico areas and neighborhoods for the activities you enjoy most.
Equipetrol
Though Equipetrol might not have many top sights, you can venture to the surrounding area to see attractions like Santa Cruz Zoo and Municipal Library.
Hamacas
While Hamacas isn't home to many top sights, Las Brisas Shopping Center and Santa Cruz Zoo are some notable places to visit nearby.
Zona Sur (South Zone)
Zona Sur (South Zone) might not have many top sights, but Ramon Tahuichi Aguilera Stadium and Plaza 24 de Septiembre are two attractions nearby that you can check out.
Urubó
While Urubó might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Guembe Biocenter and Ventura Mall.
