Find hotels in Santa Cruz Amilpas, Oaxaca

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
Dec 28 - Dec 29
Tomorrow
Dec 29 - Dec 30
Next weekend
Jan 2 - Jan 4
In two weeks
Jan 9 - Jan 11

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Cruz Amilpas hotels

Hallway
Agrado Guest House

Agrado Guest House

Agrado Guest House
3.0 star property
Ruta Independencia, 4.2 km from Santa Cruz Amilpas
8.6 out of 10, Excellent, (122)
"Very spacious and good location."
United States
Miguel
The price is ￥23,563
￥28,040 total
includes taxes & fees
Jan 18 - Jan 19, 2026
Agrado Guest House
Deluxe Suite, 1 King Bed, Pool View | Minibar, free WiFi, bed sheets
Lar Syrah

Lar Syrah

Lar Syrah
2.0 star property
Ruta Independencia, 4.2 km from Santa Cruz Amilpas
9.4 out of 10, Exceptional, (9)
"Estupendo alojamiento. La ubicación es excelente y las instalaciones son bonitas, modernas y limpias. Servicio atento, Araceli nos apoyó con recomendaciones y para solicitar un taxi. Muy recomendable."
Mexico
Elizabeth
The price is ￥21,941
￥26,110 total
includes taxes & fees
Jan 15 - Jan 16, 2026
Lar Syrah
Classic Double Room, Courtyard View | View from room
Casa Arrona Oaxaca

Casa Arrona Oaxaca

Casa Arrona Oaxaca
3.0 star property
Ruta Independencia, 4.9 km from Santa Cruz Amilpas
10.0 out of 10, Exceptional, (11)
"Excelente atención. Esperemos que siga igual"
Mexico
Martha Penelope
The price is ￥23,403
￥27,850 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Casa Arrona Oaxaca
Reception
Casa Ziña

Casa Ziña

Casa Ziña
2.0 star property
Oaxaca Centro, 4.7 km from Santa Cruz Amilpas
10.0 out of 10, Exceptional, (1)
"Fantastic hotel! Staff were super helpful and attentive. Great central location very close to Mercado 20 de Noviembre. They also provide a 3 hour car service if you want for around $130 dollars which is super helpful for seeing sites such as Monte Albán. The room was small but cosy with lots of amenities provided (including a filter coffee machine which we greatly appreciated!). The rooftop had a stunning view with a small heated pool which was great to relax in after a day of walking around...
United Kingdom
George
The price is ￥24,039
￥28,606 total
includes taxes & fees
Jan 24 - Jan 25, 2026
Casa Ziña
Terrace/patio
Casa Acueducto

Casa Acueducto

Casa Acueducto
4.0 star property
5.2 km from Santa Cruz Amilpas
9.6 out of 10, Exceptional, (32)
" Host were super friendly, Conveniently located within walking distance from many places. Place was always clean,"
United States
JOSE E
Casa Acueducto
Daily continental breakfast (MXN 320 per person)
Hotel San Felipe

Hotel San Felipe

Hotel San Felipe
3.0 star property
San Felipe del Agua, 5.9 km from Santa Cruz Amilpas
10.0 out of 10, Exceptional, (1)
"Fue una estancia muy tranquila. Sería ideal el agua templada de la alberca.en el baño de la habitación sería agradable un estractor eléctrico de vapor por ducha y uso del sanitario. Las habitaciones están perfectas las camas super cómodas las almohadas también son cómodas.. y agradables.. El TV jamás me funciono el control y el aire acondicionado no lo use. El restaurante muy agradable y el servicio super bien. Espero regresar muy pronto.."
Mexico
Nenufar
The price is ￥15,651
￥18,625 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Hotel San Felipe
Interior
ArcoSodi Hotel Boutique

ArcoSodi Hotel Boutique

ArcoSodi Hotel Boutique
3.0 star property
Ruta Independencia, 3.9 km from Santa Cruz Amilpas
9.6 out of 10, Exceptional, (57)
"Breakfast is good. The locationbosbgood too"
United States
Francisco Raimundo
ArcoSodi Hotel Boutique
Exterior
Hotel Ferri

Hotel Ferri

Hotel Ferri
3.0 star property
Oaxaca Centro, 4.8 km from Santa Cruz Amilpas
8.8 out of 10, Excellent, (31)
"Yes room was clean & the location was excellent staff was very helpful great place to stay. "
United States
Irshad Ali
Hotel Ferri
Standard Double Room, Balcony, City View | In-room safe, laptop workspace, blackout drapes, free WiFi
Hotel Casa Kabii

Hotel Casa Kabii

Hotel Casa Kabii
2.0 star property
Oaxaca Centro, 4.8 km from Santa Cruz Amilpas
9.8 out of 10, Exceptional, (6)
"HOTEL PEQUEÑO, LIMPIO, BUENA ATENCION, CERCA ZOCALO OAXACA Y MUY TRANQUILO. LO RECOMIENDO "
Mexico
José Antonio
The price is ￥16,160
￥19,230 total
includes taxes & fees
Dec 30 - Dec 31
Hotel Casa Kabii
Daily continental breakfast (MXN 140 per person)
Viajero Oaxaca Hostel

Viajero Oaxaca Hostel

Viajero Oaxaca Hostel
2.5 star property
Ruta Independencia, 4.9 km from Santa Cruz Amilpas
9.4 out of 10, Exceptional, (60)
"It was very nice place "
United States
Calvin
Viajero Oaxaca Hostel
Terrace/patio
Lidia Anturios Suites

Lidia Anturios Suites

Lidia Anturios Suites
2.0 star property
Oaxaca Centro, 4 km from Santa Cruz Amilpas
9.4 out of 10, Exceptional, (13)
"Todo muy bien "
Mexico
Conrado
The price is ￥6,932
￥8,249 total
includes taxes & fees
Jan 7 - Jan 8, 2026
Lidia Anturios Suites
Family Studio, Non Smoking | Desk, laptop workspace, free WiFi, bed sheets
Hotel escalada - Oax Up Suites

Hotel escalada - Oax Up Suites

Hotel escalada - Oax Up Suites
2.5 star property
3.4 km from Santa Cruz Amilpas
8.4 out of 10, Very Good, (54)
"The hotel is very functional, simple and minimalist. Everything worked fine, parking was very safe and efficient. The same goes for the rooms, no luxury just a clean room and comfortable bed. I would stay here again."
United States
Gerardo
The price is ￥10,573
￥12,582 total
includes taxes & fees
Jan 9 - Jan 10, 2026
Hotel escalada - Oax Up Suites
Terrace/patio
Hotel Rustiko

Hotel Rustiko

Hotel Rustiko
3.0 star property
San Sebastián Tutla, 2.1 km from Santa Cruz Amilpas
8.4 out of 10, Very Good, (44)
"They have cockroaches in the room. The room wasn’t very clean."
United States
Librado
The price is ￥8,264
￥9,834 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Hotel Rustiko
28-inch flat-screen TV with cable channels
Hotel Antiguo Fortin

Hotel Antiguo Fortin

Hotel Antiguo Fortin
2.5 star property
6.7 km from Santa Cruz Amilpas
7.6 out of 10, Good, (122)
"Good place to stay "
United States
Nidia
Hotel Antiguo Fortin
Yoga
Los Olivos Spa

Los Olivos Spa

Los Olivos Spa
3.0 star property
Calzada Madero, 6.8 km from Santa Cruz Amilpas
8.2 out of 10, Very Good, (184)
"My family stayed here for five nights total and it was the best hotel for us. Great service, clean, with a very nice restaurant with delicious food. We tried a massage and that was wonderful as well! The hotel's landscape and garden are gorgeous and well-maintained. Thank you!"
United States
Aileen
The price is ￥12,593
￥15,138 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Los Olivos Spa
Outdoor pool
Hotel Santa Helena Plaza

Hotel Santa Helena Plaza

Hotel Santa Helena Plaza
2.5 star property
Oaxaca Centro, 5 km from Santa Cruz Amilpas
8.4 out of 10, Very Good, (93)
"Loved the location, just a short walk to the Mercado and Zocalo. "
United States
elizabeth
The price is ￥11,364
￥13,523 total
includes taxes & fees
Jan 28 - Jan 29, 2026
Hotel Santa Helena Plaza
KUNI | In-room safe, blackout drapes, iron/ironing board, free WiFi
Flavia Hotel

Flavia Hotel

Flavia Hotel
3.0 star property
San Felipe del Agua, 7.5 km from Santa Cruz Amilpas
9.0 out of 10, Wonderful, (85)
"Todo excelente "
Mexico
Montserrat
The price is ￥27,447
￥33,730 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Flavia Hotel
Standard Double Room, 1 Double Bed | Desk, laptop workspace, free WiFi, bed sheets
HOTEL POSADA DON MATIAS

HOTEL POSADA DON MATIAS

HOTEL POSADA DON MATIAS
2.0 star property
Oaxaca Centro, 4.7 km from Santa Cruz Amilpas
9.0 out of 10, Wonderful, (200)
"Great place!"
United States
Josias
The price is ￥5,355
￥6,372 total
includes taxes & fees
Jan 27 - Jan 28, 2026
HOTEL POSADA DON MATIAS
Property amenity
City Centro by Marriott Oaxaca

City Centro by Marriott Oaxaca

City Centro by Marriott Oaxaca
3.5 star property
Jalatlaco, 3.9 km from Santa Cruz Amilpas
9.0 out of 10, Wonderful, (761)
"I absolutely loved my stay at city centro. It’s beautiful, the room was perfect, the staff & amenities were 10/10 and the bed was comfortable. I will definitely be back & will recommend this hotel to all my friends and family when visiting Oaxaca. "
United States
Armando Daniel
The price is ￥26,287
￥31,282 total
includes taxes & fees
Jan 6 - Jan 7, 2026
City Centro by Marriott Oaxaca
Interior
Hotel Oaxaca Inn Reforma

Hotel Oaxaca Inn Reforma

Hotel Oaxaca Inn Reforma
3.0 star property
Reforma, 4.3 km from Santa Cruz Amilpas
8.0 out of 10, Very Good, (62)
"Excellent service! "
United States
Fernando
The price is ￥10,621
￥12,639 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Hotel Oaxaca Inn Reforma
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Santa Cruz Amilpas

Find the best Santa Cruz Amilpas areas and neighborhoods for the activities you enjoy most.
Oaxaca which includes a city
Photo by PhotoJoy
Open Photo by PhotoJoy

Oaxaca Centro

Discover colonial-era structures and immerse in native Zapotec and Mixtec cultures in this UNESCO World Heritage Site. Explore the archeological marvel of Monte Albán and admire the unique green stone architecture.

Ruta Independencia

If you're spending some time in Ruta Independencia, Oaxaca Ethnobotanical Garden and Jardín Etnobotánico are top sights worth seeing.

Jalatlaco

While Jalatlaco isn't home to many top sights, El Llano Park and Oaxaca Ethnobotanical Garden are some notable places to visit nearby.

Reforma

If you're spending some time in Reforma, Plaza Mazari and Plaza Parque are top sights worth seeing.

San Agustín Yatareni

While there might not be top attractions in San Agustín Yatareni, you can explore the larger area and discover places like El Llano Park and Oaxaca Ethnobotanical Garden.

Top Santa Cruz Amilpas Hotel Reviews

Quinta Real Oaxaca

Quinta Real Oaxaca

10/10 Excellent
"Muy bien servicio, excelente atención, en especial de Javier quien nos dio muy buenas recomendaciones y sugerencias para visitar y comer. El hotel estupendo "
Genevieve 4-night trip
Posted 2 days ago
Quinta Real Oaxaca

Frequently asked questions

What is Santa Cruz Amilpas like?
Travelers to the Santa Cruz Amilpas neighborhood in Oaxaca will be sure to enjoy their stay. Consider a visit to Clases De Karate Do Shito Kai Ittoo Juku as part of your Santa Cruz Amilpas travel plans.
If I need to cancel my hotel reservation in Santa Cruz Amilpas, will I receive a refund?
Yes! Most hotel bookings are fully refundable if cancelled before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of your booking. Add dates, click "Search", then you can use the "fully refundable" filter to view the top deals on offer in Santa Cruz Amilpas.
Where can I learn more about changing or cancelling my trip to Santa Cruz Amilpas?
To find more details about updating your trip to Santa Cruz Amilpas or cancelling it, head over to our customer service page.
What are the top things to see and do in Santa Cruz Amilpas?
Clases De Karate Do Shito Kai Ittoo Juku is an attraction you might want to check out while you're in Santa Cruz Amilpas. A Los Pinos Trailhead and Calle Alcalá are also worth a visit when you're out sightseeing in Oaxaca.

Explore a world of travel with Expedia