The Best Resorts & Hotels with Spas in Santa Ana, CA from ￥16,307 in 2026

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Our top choices for Santa Ana hotels with a spa

A Comfort Inn hotel with a modern facade, palm trees, and a sunset sky.

1. Comfort Inn Anaheim Resort

Anaheim Resort

Rejuvenate at this full-service spa hotel with hot tub and pool, minutes from Disneyland Resort.

￥22,775 total

includes taxes & fees

Dec 1 - Dec 2

A spacious lobby with a large arched glass door, a chandelier, and a seating area with a sofa and chairs.

2. Best Western Plus Newport Mesa Inn

Costa Mesa

Experience a rejuvenating escape at this hotel with a full-service spa, outdoor pool, and hot tub for a blissful wellness retreat.

￥24,541 total

includes taxes & fees

Nov 23 - Nov 24

A modern bedroom with a bed, a wooden wardrobe, and a wall-mounted vanity with a marble-like design.

3. Disneyland Hotel

Anaheim Resort

￥124,420 total

includes taxes & fees

Nov 12 - Nov 13

The exterior of Tenaya Stone Spa with a large sign, a wooden door, and potted plants.

4. Disney's Grand Californian Hotel and Spa

Anaheim Resort

￥161,376 total

includes taxes & fees

Nov 17 - Nov 18

A reception area with a wooden reception desk, a chandelier, wicker chairs, and a decorative bowl on a round table.

5. The Waterfront Beach Resort, A Hilton Hotel

Huntington Beach

Rejuvenate at this beachfront resort with 9 treatment rooms, couples massages, and outdoor spa areas overlooking the ocean.

￥48,683 total

includes taxes & fees

Nov 22 - Nov 23

A Marriott Residence Inn with a covered entrance, palm trees, and landscaped gardens.

6. Residence Inn by Marriott Cypress Los Alamitos

Los Alamitos

￥31,381 total

includes taxes & fees

Nov 22 - Nov 23

A well-lit reception area with a counter, chairs, a mirror, and a display of products.

7. Ayres Hotel & Spa Mission Viejo – Lake Forest

Mission Viejo

Revitalize with luxurious spa treatments, mountain views, and a serene outdoor pool at this relaxing retreat.

￥17,644 total

includes taxes & fees

Nov 30 - Dec 1

A modern bathroom with a freestanding bathtub, two separate beds with towels, and a decorative wall panel.

8. Paséa Hotel & Spa

Pacific City

Rejuvenating spa sanctuary offers coastal bliss with outdoor treatment areas and hot stone massages.

￥53,446 total

includes taxes & fees

Nov 29 - Nov 30

A spacious living room with a large wooden surfboard, a fireplace, a dining area, and a view of the ocean through arched windows.

9. Hyatt Regency Huntington Beach Resort and Spa

Huntington Beach

Coastal retreat with 17 spa treatment rooms and 5 hot tubs awaits, offering massages and aromatherapy in Mediterranean elegance.

￥55,177 total

includes taxes & fees

Nov 22 - Nov 23

A modern bar area with a central island, bar stools, pendant lighting, and a view through large windows.

10. Holiday Inn Diamond Bar - Pomona by IHG

Diamond Bar

Indulge in a full-service spa experience at this Diamond Bar hotel featuring a hot tub, outdoor pool, and rejuvenating wellness options.

￥20,930 total

includes taxes & fees

Dec 9 - Dec 10

View all properties

Choose what matters most at spa hotels in Santa Ana

Pool

Hot tub

Top Santa Ana Hotel Reviews

Comfort Inn Anaheim Resort

Anaheim Resort

10/10 Excellent

Maria

Best Western Plus Newport Mesa Inn

Costa Mesa

10/10 Excellent

I was there for 3 nights. On the second night, the jerks in room 216 decided it was appropriate to throw a party at 1:30 am; music, noise, loud voices, etc. At 2:15, I called the front desk to complain; 15 minutes later, the music stopped, but the noise and loud voices continued until 3:30. Finally they shut up and I was able to get back to sleep. That morning, at the front desk, I mentioned what happened to Norm. He was very apologetic. He offered a suggestion (that I be moved into another...

Elizabeth

The Waterfront Beach Resort, A Hilton Hotel

Huntington Beach

10/10 Excellent

Karen

The Villas At The Disneyland Hotel

Anaheim Resort

10/10 Excellent

Glenn

Ayres Hotel & Spa Mission Viejo – Lake Forest

Mission Viejo

10/10 Excellent

Maria

Hyatt Regency Huntington Beach Resort and Spa

Huntington Beach

10/10 Excellent

Paul

Disney's Grand Californian Hotel and Spa

Anaheim Resort

10/10 Excellent

Cassandra

Residence Inn by Marriott Cypress Los Alamitos

Los Alamitos

10/10 Excellent

Lester

A modern lobby with seating arrangements, decorative mirrors, and a chandelier.

Balboa Bay Resort

Newport Heights

10/10 Excellent

Andrew

A building with a spa sign and a massage sign.

Casa Laguna Hotel & Spa

Laguna Beach

10/10 Excellent

Courtney

Holiday Inn Diamond Bar - Pomona by IHG

Diamond Bar

10/10 Excellent

My family and I stayed here from Dec 28 - Jan 3rd and it was a wonderful experience. We had booked another hotel originally that was absolutely disgusting and roach infested. We searched online for a good hotel and found this Holiday Inn. It was the best decision I made and regret not booking this hotel first. I will never stay anywhere else but here. The staff was extremely helpful upon our arrival at midnight on December 28th with two very tired children, I wish I could remember the...

Jackie

A couple sitting on a wicker sofa with a view of the ocean. There are two wicker chairs and a table with a drink on it.

Surf & Sand Laguna Beach

Pearl District

10/10 Excellent

A Slice of Paradise at Surf & Sand Laguna From the moment you step onto the property, Surf & Sand Laguna wraps you in the kind of coastal magic only Laguna Beach can offer. The sound of crashing waves greets you the second you check in—because yes, the beach is truly right there. It’s like waking up inside a dream, where every room has a front-row seat to the Pacific Ocean. Surf & Sand is more than a resort—it’s a soulful escape where we as a family can slow down, breathe deeply, and reconnect...

Shabnam

A spa room with two massage tables, a stone wall, and a large window with curtains.

The Ranch at Laguna Beach

South Laguna

10/10 Excellent

Tim

A person receiving a back massage in a room with a bed and a wall-mounted rack.

Montage Laguna Beach

South Laguna

10/10 Excellent

Beautiful location. A little busy though. There were two weddings and a huge baby shower the weekend we were there. We had a ground level suite with a patio and we felt like we were in a fishbowl because the events were right off of our patio. Most of the staff were phenomenal and exceptionally good at their jobs. A few of the staff were a little clueless and contradicted their exceptional colleagues. The food was really exceptional. Perhaps the best resort food I have ever experienced.

Anonymous traveler

An outdoor seating area with rows of chairs and tables, a stone pathway, and a building with large windows and balconies in the background.

Inn at the Mission San Juan Capistrano, Autograph Collection by Marriott

Downtown

10/10 Excellent

Lynn

Frequently Asked Questions

Looking for a spa hotel in Santa Ana?

Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travelers like the beaches and popular shops in Santa Ana so get ready for a day of fun. Take in the culture at the museums and art galleries during your stay. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.

What's there to see and do in Santa Ana?

Take in some sights and attractions while you're in Santa Ana by visiting Old Orange County Courthouse, Bowers Museum, and Santa Ana Zoo. If you have a bit of extra time while you’re in the area, you might want to check out Heritage Museum of Orange County and The Observatory.

What is a Santa Ana spa hotel?

Spa hotels in Santa Ana provide lodging and have an on-site spa which offers services like therapies as well as body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.

Find Resorts & Hotels with Spas in Santa Ana, CA

Change your mind

Treat yourself

Be picky

Check prices for these dates

Our top choices for Santa Ana hotels with a spa

1. Comfort Inn Anaheim Resort

2. Best Western Plus Newport Mesa Inn

3. Disneyland Hotel

4. Disney's Grand Californian Hotel and Spa

5. The Waterfront Beach Resort, A Hilton Hotel

6. Residence Inn by Marriott Cypress Los Alamitos

7. Ayres Hotel & Spa Mission Viejo – Lake Forest

8. Paséa Hotel & Spa

9. Hyatt Regency Huntington Beach Resort and Spa

10. Holiday Inn Diamond Bar - Pomona by IHG

Choose what matters most at spa hotels in Santa Ana

Top Santa Ana Hotel Reviews

Comfort Inn Anaheim Resort

10/10 Excellent

Frequently Asked Questions

Looking for a spa hotel in Santa Ana?

What's there to see and do in Santa Ana?

What is a Santa Ana spa hotel?