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Our top choices for Sanibel vacation homes

1. Driftwood Inn

Driftwood Inn
4.0 star property
Mid Island
10.0 out of 10, Exceptional, (11 reviews)
"Great place to stay on sanibel"
United States
Terri
The price is ¥30,616
¥72,027 total
includes taxes & fees
Nov 8 - Nov 9
Driftwood Inn

2. Sandals and Flip Flops, #301

Sandals and Flip Flops, #301
Mid Island
9.0 out of 10, Wonderful, (42 reviews)
"Easy walk to beach. Easy parking. Cheerful decor"
United States
Mark
The price is ¥48,050
¥82,438 total
includes taxes & fees
Nov 8 - Nov 9
Sandals and Flip Flops, #301

3. Palm Retreat Cottage at Palmview Inn of Sanibel

Palm Retreat Cottage at Palmview Inn of Sanibel
Mid Island
9.8 out of 10, Exceptional, (15 reviews)
"Beautiful home, extremely clean, close to everything!"
United States
Nannette C.
The price is ¥70,556
¥114,641 total
includes taxes & fees
Nov 23 - Nov 24
Palm Retreat Cottage at Palmview Inn of Sanibel

4. coastal chic cottage "Heron" minutes to the beach! JULY SAVINGS!

coastal chic cottage "Heron" minutes to the beach! JULY SAVINGS!
West End
9.2 out of 10, Wonderful, (45 reviews)
"This was my second stay . It’s so amazing and the location is perfect !!!! We will be back !"
United States
EMILY B.
The price is ¥26,773
¥70,245 total
includes taxes & fees
Nov 10 - Nov 11
coastal chic cottage "Heron" minutes to the beach! JULY SAVINGS!

5. Beach Lovers Welcome, #303

Beach Lovers Welcome, #303
Mid Island
9.4 out of 10, Exceptional, (29 reviews)
"Great place and close to the beach!"
United States
Steve W.
The price is ¥50,720
¥85,569 total
includes taxes & fees
Nov 8 - Nov 9
Beach Lovers Welcome, #303

6. Caloosa Retreat- 2BR at Palmview Inn Sanibel

Caloosa Retreat- 2BR at Palmview Inn Sanibel
Mid Island
9.4 out of 10, Exceptional, (3 reviews)
"We absolutely loved the unit. My wife and I have already decided we will be staying again with our next trip to Sanibel. Couldn’t be happier with our stay!"
United States
Jordan O.
Caloosa Retreat- 2BR at Palmview Inn Sanibel

7. Lakeside Oasis

Lakeside Oasis
2.0 star property
Iona
The price is ¥17,996
¥39,382 total
includes taxes & fees
Nov 9 - Nov 10
Lakeside Oasis

8. Gorgeous relaxing 2BD Near Ft. Myers Beach

Gorgeous relaxing 2BD Near Ft. Myers Beach
Iona
10.0 out of 10, Exceptional, (10 reviews)
"Nice quiet and clean olace to stay"
United States
Henry H.
The price is ¥14,174
¥39,015 total
includes taxes & fees
Nov 8 - Nov 9
Gorgeous relaxing 2BD Near Ft. Myers Beach

9. 3-bedroom house in charming Saint James City with Canal Views!

3-bedroom house in charming Saint James City with Canal Views!
Saint James City
10.0 out of 10, Exceptional, (12 reviews)
"Nice place with good fishing in the canal. "
United States
Joshua A.
The price is ¥27,542
¥72,157 total
includes taxes & fees
Nov 8 - Nov 9
3-bedroom house in charming Saint James City with Canal Views!

10. "Relax and Unwind" Peaceful 2-bedroom house in Fort Myers Beach

"Relax and Unwind" Peaceful 2-bedroom house in Fort Myers Beach
Fort Myers Beach
9.8 out of 10, Exceptional, (10 reviews)
"Our hosts were wonderful and the property was clean"
United States
Amy T.
The price is ¥21,419
¥60,892 total
includes taxes & fees
Nov 8 - Nov 9
"Relax and Unwind" Peaceful 2-bedroom house in Fort Myers Beach

11. Beach Bliss~Walk to Beach & Times Square~Private Pool

Beach Bliss~Walk to Beach & Times Square~Private Pool
Fort Myers Beach
9.8 out of 10, Exceptional, (25 reviews)
"Perfect location, great long weekend with friends."
United States
Jennifer B.
The price is ¥28,191
¥71,436 total
includes taxes & fees
Nov 15 - Nov 16
Beach Bliss~Walk to Beach & Times Square~Private Pool

12. Fisherman's Delight With Heated Salt Swimming Pool and a new Boat Lift

Fisherman's Delight With Heated Salt Swimming Pool and a new Boat Lift
St James City
9.6 out of 10, Exceptional, (97 reviews)
"Beautiful home easy access to gulf and awesome cool pool definitely will be back"
United States
Travis W.
The price is ¥36,065
¥84,062 total
includes taxes & fees
Dec 3 - Dec 4
Fisherman's Delight With Heated Salt Swimming Pool and a new Boat Lift

13. Bright & Airy 2bed 2bath home near downtown/Weekly and monthly discounts!

Bright & Airy 2bed 2bath home near downtown/Weekly and monthly discounts!
Pelican
9.6 out of 10, Exceptional, (63 reviews)
"House was very clean and looked just like advertised. Had a very comfortable stay and property is close to everything you need. Will definitely come back."
United States
Jennifer B.
The price is ¥16,379
¥37,713 total
includes taxes & fees
Nov 21 - Nov 22
Bright & Airy 2bed 2bath home near downtown/Weekly and monthly discounts!

14. NEW REMODEL Steps from private beach access! 4 BR Family Friendly CLEAN

NEW REMODEL Steps from private beach access! 4 BR Family Friendly CLEAN
Mid Island
9.4 out of 10, Exceptional, (38 reviews)
"It was exactly what we needed for our girls trip! Host was responsive and the place had everything we needed for going to the beach!"
United States
Hannah H.
The price is ¥48,979
¥105,581 total
includes taxes & fees
Nov 23 - Nov 24
NEW REMODEL Steps from private beach access! 4 BR Family Friendly CLEAN

15. Endless Summer Hideaway w/Pool/ocean access/5br

Endless Summer Hideaway w/Pool/ocean access/5br
Pelican
8.8 out of 10, Excellent, (26 reviews)
"Wonderful place to stay"
United States
Becky W.
The price is ¥36,695
¥79,342 total
includes taxes & fees
Nov 16 - Nov 17
Endless Summer Hideaway w/Pool/ocean access/5br

16. Enjoy a 3-bedroom vacation home in Yacht Club - Special January & February.

Enjoy a 3-bedroom vacation home in Yacht Club - Special January & February.
Caloosahatchee
9.6 out of 10, Exceptional, (122 reviews)
"Close to restaurants and the beach. Nice house overall."
United States
Paul L.
The price is ¥24,290
¥68,412 total
includes taxes & fees
Nov 8 - Nov 9
Enjoy a 3-bedroom vacation home in Yacht Club - Special January & February.

17. Waterfront Home: Private Pool & Stunning Sea Views

Waterfront Home: Private Pool & Stunning Sea Views
Pelican
10.0 out of 10, Exceptional, (8 reviews)
"Overall, was a wonderful stay and a beautiful home. "
United States
Kyra S.
The price is ¥18,741
¥71,658 total
includes taxes & fees
Nov 17 - Nov 18
Waterfront Home: Private Pool & Stunning Sea Views

18. The Waterfront Fishing Retreat – Luxury • Water Views • Private Dock

The Waterfront Fishing Retreat – Luxury • Water Views • Private Dock
Pelican
9.6 out of 10, Exceptional, (4 reviews)
"Location on VRBO map was inaccurate as it presents with the pool facing west on the opposite side of this eight lake. The home itself was immaculate, the pool however was filthy. I contacted the owner/manager the first morning of my four night stay and it was cleaned the last day of our stay, so that was disappointing."
United States
Sarah S.
The price is ¥25,655
¥77,860 total
includes taxes & fees
Nov 9 - Nov 10
The Waterfront Fishing Retreat – Luxury • Water Views • Private Dock

19. Fabulous 5 BR Waterfront Villa for Your Perfect Dream Vacation!

Fabulous 5 BR Waterfront Villa for Your Perfect Dream Vacation!
Pelican
9.8 out of 10, Exceptional, (50 reviews)
"Wonderful pool, lanai, view. Great family fun vacation. "
United States
Mary Kay S.
The price is ¥36,711
¥181,566 total
includes taxes & fees
Nov 8 - Nov 9
Fabulous 5 BR Waterfront Villa for Your Perfect Dream Vacation!

20. Modern boho 2bed 2bath home, 8 mins to downtown cape and near beach.

Modern boho 2bed 2bath home, 8 mins to downtown cape and near beach.
Pelican
9.4 out of 10, Exceptional, (42 reviews)
"Everything was as listed! My husband and I had a great stay while visiting friends. Location was perfect and the space was super cozy! Would definitely recommend!"
United States
julie l.
The price is ¥14,883
¥35,257 total
includes taxes & fees
Nov 11 - Nov 12
Modern boho 2bed 2bath home, 8 mins to downtown cape and near beach.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Sanibel

Shell-seekers flock to pristine beaches where the 'Sanibel Stoop' is the local posture for finding perfect specimens. Bike the 25-mile trail network through wildlife refuges where alligators sunbathe and over 245 bird species can be spotted with binoculars.

A wooden boardwalk leading to J.N. Ding Darling National Wildlife Refuge Visitor & Education Center, surrounded by lush greenery.