San Isidro Vacations

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  • Better together

    Save up to ¥109,000 when you book a flight and hotel together*
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    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place
Price found within the past 48 hours. Click for updated prices.
  • Jul 2 - Jul 5

    Relais & Châteaux Heritage Madrid + Flight

    Salamanca
    2 nights
    5.0 star property
    9.6/10 - Exceptional (584 reviews)
    Roundtrip Osaka (KIX) - Madrid (MAD)
    KIX - MAD1 stop MAD - KIX1 stop
    ¥243,123
    ¥207,694
    per traveler
    found 21 hours ago
    Relais & Châteaux Heritage Madrid
  • Aug 10 - Aug 14

    Hotel Riu Plaza España + Flight

    Madrid Centro
    4 nights
    4.0 star property
    9.4/10 - Exceptional (4,866 reviews)
    "clean room, breakfast was good"
    Reviewed May 21, 2026
    Roundtrip Tokyo (HND) - Madrid (MAD)
    HND - MAD1 stop MAD - HND1 stop
    ¥326,146
    ¥261,581
    per traveler
    found 1 day ago
    Hotel Riu Plaza España
  • Jul 5 - Jul 9

    Hotel Atlantico Madrid + Flight

    Madrid Centro
    3 nights
    4.0 star property
    9.8/10 - Exceptional (2,188 reviews)
    "A fantastic location in the heart of the Gran Via with amazing views from its roof top patios. The staff were so welcoming and helpful it made our stay a very special one."
    Reviewed May 21, 2026
    Roundtrip Tokyo (NRT) - Madrid (MAD)
    NRT - MAD1 stop MAD - HND1 stop
    ¥261,865
    ¥223,272
    per traveler
    found 23 hours ago
    Hotel Atlantico Madrid
  • Aug 10 - Aug 14

    Barceló Emperatriz + Flight

    Salamanca
    4 nights
    5.0 star property
    9.6/10 - Exceptional (1,173 reviews)
    "Nice room "
    Reviewed May 20, 2026
    Roundtrip Tokyo (HND) - Madrid (MAD)
    HND - MAD1 stop MAD - HND1 stop
    ¥311,816
    ¥267,421
    per traveler
    found 1 day ago
    Barceló Emperatriz
  • Aug 10 - Aug 14

    Melia Madrid Princesa + Flight

    Moncloa - Arguelles
    4 nights
    5.0 star property
    9.0/10 - Wonderful (1,001 reviews)
    "Hotel is under renovation so it can be a problem to enter and exit. "
    Reviewed May 20, 2026
    Roundtrip Tokyo (HND) - Madrid (MAD)
    HND - MAD1 stop MAD - HND1 stop
    ¥302,495
    ¥264,917
    per traveler
    found 1 day ago
    Melia Madrid Princesa

Where to stay in San Isidro

Find the best San Isidro areas and neighborhoods for the activities you enjoy most. Learn more about San Isidro

San Isidro Hotel Deals

NH Collection Salamanca Palacio de Castellanos

NH Collection Salamanca Palacio de Castellanos

4 out of 5
Calle San Pablo, 58 Salamanca Salamanca
Fully refundableReserve now, pay when you stay
The price is ¥22,330 per night from Jun 7 to Jun 8
¥22,330
¥24,563 total
Jun 7 - Jun 8
includes taxes & fees
9.4/10 Exceptional! (663 reviews)
"One of the best hotels I’ve stayed at in Europe. Everything about it was lovely, the people were so polite, and the breakfast staff truly went above and beyond to make sure you had everything you wanted. Honestly, it was such a beautiful place to be; the photos don’t do it justice at all. The breakfast ..."

Reviewed on May 10, 2026

NH Collection Salamanca Palacio de Castellanos
Hotel Gran Vía by gaiarooms

Hotel Gran Vía by gaiarooms

3 out of 5
Calle la Rosa 4 Salamanca Salamanca
Fully refundableReserve now, pay when you stay
The price is ¥7,554 per night from May 24 to May 25
¥7,554
¥8,309 total
May 24 - May 25
includes taxes & fees
8.8/10 Excellent! (83 reviews)
"Very clea, great location but noisy on a Friday night."

Reviewed on May 18, 2026

Hotel Gran Vía by gaiarooms
Hotel Mercado by gaiarooms

Hotel Mercado by gaiarooms

3 out of 5
Calle San Juan de la Cruz 7 Salamanca
Fully refundableReserve now, pay when you stay
The price is ¥5,877 per night from May 24 to May 25
¥5,877
¥6,465 total
May 24 - May 25
includes taxes & fees
8/10 Very Good! (88 reviews)
"The ac does not work. The area is very noise impossible to sleep before 3 am"

Reviewed on May 20, 2026

Hotel Mercado by gaiarooms
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a San Isidro vacation package cost?
From as low as . Yes, you read that correctly. Our San Isidro packages are an awesome way to make your budget go further. Bundle your preferred flights, hotels and rental car and explore this vibrant destination.
How do I get a cheap travel package to San Isidro?
Browse and book everything in one place with our San Isidro vacation packages. You'll find deals on flights, hotels, tours and more that'll keep your travel budget happy and your adventurous side busy. And, with more than 550 partner airlines and 1,000,000 hotels around the globe to pick from, there are endless opportunities to mix and match your own way.
Where should I stay in San Isidro?
Vacationers come from all corners of the globe to see New Cathedral of Salamanca and San Esteban Convent in San Isidro. Book a room close to these awesome attractions and visit them at your leisure.
How far in advance should I book my San Isidro vacation?
While not all air carriers release ticket prices early, it's usually possible to compare international airfares on Expedia up to 12 months in advance. This is when you can bag some incredible deals. If you're booking last minute, you might get lucky. Low prices occasionally emerge only weeks before departure.
What does an Expedia San Isidro travel package include?
Much of that is up to you. You can pick from a variety of San Isidro packages, such as a hotel, rental car and flight. You can also book a hotel with a flight, or a rental car and a flight. Once you've made your booking, you can add on the fun stuff like experiences and tours. Whatever your ideal San Isidro trip looks like, get ready to save!
What should I know before booking a San Isidro travel package?
A travel package can be tailored to your budget and is a terrific way to make your hard-earned dollars stretch further. How much you include is up to you. Rental cars, hotels and flights — mix and match whatever combination suits your style.
Can I choose my airline with a San Isidro Expedia vacation package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines throughout the world. Our packages give you the freedom to pick from available flight, hotel or activity options that fit your needs.
If I'm not able to travel, can I cancel my San Isidro vacation package?
Because we know life can throw you a few curveballs, the answer is yes. For more information, check out our Customer Service Portal. But generally speaking, if you've booked your San Isidro vacation package in the last 24 hours, you may be able to cancel or change it without penalty. Your airline, hotel or car rental company may impose a fee if your booking is older than that.

Discover the most popular places to visit in San Isidro

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.