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Due to coronavirus (COVID-19) travel advisories, some destinations may be unavailable for certain dates. Find out more.
Due to coronavirus (COVID-19) travel advisories, some destinations may be unavailable for certain dates. Find out more.

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Panama Vacation

While Panama is perhaps best known for its mighty canal, there’s so much more to this Central American country. Visitors will also be wowed by lush rainforests, idyllic beaches, rich indigenous culture and a unique colonial history.

Panama Hotel + Flights

Expedia has 1270 hotels available here starting at ¥4,334 a night. But if you want to save some serious money, combine your hotel and flights into a Panama Vacation Package. You can also add car rental and activities to your booking to create an unforgettable getaway. With the dollars you save, why not book a tour and visit island paradises or taste famous local flavors like ceviche?


Your Panama Vacation Itinerary

  • Day 1-2: Start your adventure in the national capital, Panama City, and head straight to Casco Viejo (the Old Quarter). Wander narrow cobblestone streets and discover colorful Spanish colonial houses, beautiful churches and an impressive gastronomic scene. Plan a day trip to the Panama Canal to watch mammoth ships slip through the Miraflores Locks.

  • Day 3-5: Stay on some of the world’s most spectacular islands in San Blas. Owned and operated by the Kuna people, this untouched paradise on the Caribbean side of Panama is the perfect place to live out your Robinson Crusoe fantasies.

  • Day 6-8: Head back to Panama City and fly to the mountain town of Boquete. A top destination for outdoor lovers, it offers jungle hikes, whitewater rafting, canopy tours, zip lining and more.

Panama Information

  • Party with the locals at Carnival, Panama’s largest annual celebration. You’ll find the biggest events in Panama City and Las Tablas.

  • If you’ll be spending most of your time in the nation’s capital, check out our Panama City Vacation Packages.

  • Want to really experience the carefree vibe of this Latin American gem? Book one of our Panama All Inclusive Resorts and say adios to vacation planning stress.

Q: Which airports can I fly in to for a vacation to Panama?

A: While there are several possibilities, you're most likely to fly in to one of these two top international terminals in Panama:

  • Panama City (PTY-Tocumen Intl.): 5,337 international flights per month.
  • David (DAV-Enrique Malek Intl.): 13 international flights per month.

Q: What are the most popular types of hotels for a vacation to Panama?

A: Many visitors like to spend their getaways in hotels. Some are fond of the amenities and services of hostels or bed & breakfasts, while others choose to book apartments. Whatever you're chasing, Panama has options for all budgets.

Q: What does a Panama vacation booking with Expedia include?

A: Car and flight. Flight and hotel. Hotel and car. Flight, hotel and car. You get the gist. You can book as much or as little as you like, all in one place. To get as much as you can out of your Panama vacation, have a look at our experiences and activities while you're at it.

Q: What is the best way to save money on my vacation to Panama?

A: You'll be rewarded handsomely when you lock in a Panama vacation package with a little help from Expedia. Bundle your Flights, Hotels and Experiences and enjoy great discounts, like up to 42% off selected properties. You'll soon be looking at your dream vacation at a price that'll pleasantly surprise you.

Q: What are the best things to do in Panama?

A: When you're staying in San Miguelito, don't miss the chance to check out Metromall Panama.

If David is your chosen destination, check out Miguel de Cervantes Saavedra Park.

Lastly, Gatun Locks is one attraction that's high on the must-do list of many vacationers in Colon.




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Best Lodging Options Near Panama

See all 1,270 Properties in Panama
Principe Hotel and Suites ¥4,334
Reviewed on Mar 29, 2020
See details
 
Principe Hotel and Suites

Principe Hotel and Suites

Via Argentina, Panama City, Panama
     
    4.2 of 5
    3.0 out of 5.0 Stars

    Was perfect!!! Very good hotel and good quality and safe

    Hyatt Place Panama City/Downtown ¥6,394
    Reviewed on Mar 10, 2020
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    Hyatt Place Panama City/Downtown

    Hyatt Place Panama City/Downtown

    Avenida Aquilino de la Guardia, between, Vía España and Calle 52 Bella Vista, Panama City, Panama
       
      4.3 of 5
      3.5 out of 5.0 Stars

      Hotel is a little worn but walking distance to restaurants. Has coin laundry on pool level which is great for multiweek travelers. Would.stay again.

      Hilton Panama ¥11,617
      Reviewed on Apr 1, 2020
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      Hilton Panama

      Hilton Panama

      Balboa Ave. and Aquilino De La Guardia, Panama City, Panama
         
        4.4 of 5
        5.0 out of 5.0 Stars

        Great location and very clean. Confusing elevator system. Expensive drinks.

        Bristol Panama ¥21,524
        Reviewed on Feb 29, 2020
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        Bristol Panama

        Bristol Panama

        Avenida Aquilino de La Guardia, Bella Vista, Panama City, Panama
           
          4.5 of 5
          5.0 out of 5.0 Stars

          Wonderful staff ! Beautiful property.

          Eurostars Panama City ¥6,198
          Reviewed on May 12, 2020
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          Eurostars Panama City

          Eurostars Panama City

          Calle Ricardo Arias, Bellavista Via Espana, Panama City, Panama
             
            4.1 of 5
            4.0 out of 5.0 Stars

            Love the room and everything about Eurostars! Excellent professional staff, clean, over all excellent!

            Los Mandarinos Boutique Spa and Hotel ¥17,906
            Reviewed on Mar 22, 2020
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            Los Mandarinos Boutique Spa and Hotel

            Los Mandarinos Boutique Spa and Hotel

            Calle Del Ciclo El Valle De Anton Cocle, El Valle de Anton, Cocle
               
              4.1 of 5
              4.0 out of 5.0 Stars

              The hotel is comfortable and clean and the staff is friendly and helpful. It is set in the outskirts of the beautiful Valle de Anton. Furthermore it has good restaurants on the hotel area.

              Dreams Playa Bonita Panama - Optional All Inclusive
              Reviewed on Mar 20, 2020
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              Dreams Playa Bonita Panama - Optional All Inclusive

              Dreams Playa Bonita Panama - Optional All Inclusive

              KM 7, Road to Veracruz, Panama City, Panama
                 
                3.8 of 5
                4.0 out of 5.0 Stars

                Staff was wonderful! Went out of their way to be helpful. Food was about what I expected at an All Inclusive (pretty good). Grounds were beautiful!

                Hard Rock Hotel Panama Megapolis ¥12,189
                Reviewed on Mar 16, 2020
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                Hard Rock Hotel Panama Megapolis

                Hard Rock Hotel Panama Megapolis

                Ave. Balboa al lado de Multicentro, Panama City, Panama
                   
                  4.2 of 5
                  4.5 out of 5.0 Stars

                  Stay was good just one night

                  Top Activities in Panama

                  See all 411 things to do in Panama