Panama City Vacations

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ¥45,448 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Panama City

Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City

Find the Best Panama City Vacation Packages

Things to do in and around Panama City

Shopping

In Panama City, visit Albrook Shopping Mall for a vibrant mix of entertainment and shopping. Explore Uruguay Street for local boutiques and family-friendly vibes. For a unique experience, check out the National Craft Market for authentic Panamanian crafts and souvenirs.

Recreation

Estadio Rommel Fernandez offers an energetic atmosphere for sports enthusiasts, perfect for invigorating workouts or enjoying local games. For a cultural experience, the National Theater showcases captivating performances, blending romance and entertainment in a vibrant setting. Meanwhile, Estadio Nacional Rod Carew provides an exciting venue for sports events, fueling your adrenaline.

Adventure

Embark on the Honeycreeper Ridge Trail, a scenic hiking experience 40.2km from Panama City, where lush landscapes await. For thrill-seekers, Gatun Eco Adventures offers an exhilarating zipline course 46.7km away, surrounded by vibrant nature and adventure vibes that will leave you breathless.

Nightlife

In Panama City, experience vibrant nightlife in areas like Casco Viejo and the Avenida Balboa. Enjoy lively bars, trendy clubs, and rooftop lounges offering stunning skyline views. Dance the night away at venues like La Tana and Teatro Amador, where local DJs and live music create an unforgettable atmosphere.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions in Panama City

Panama City, located in Panamá Province, is ideal for family, city, and business-themed vacations. Visitors can explore various points of interest, including vibrant streets, event venues, and urban parks, all catering to those seeking cultural and family experiences. Don't miss the beautiful Panama City beaches for relaxation and fun. This dynamic city offers a perfect blend of urban excitement and natural beauty for every type of traveler.

  • Avenida Balboa: Stroll along this vibrant street that runs parallel to the coastline, offering stunning views of the Pacific Ocean and the Panama City skyline. Enjoy a variety of shops, restaurants, and parks that embody the city's lively atmosphere.
  • Panama Canal Railway: Experience a historic journey on this iconic railway, which connects the Atlantic and Pacific Oceans. The scenic ride through lush landscapes and alongside the famous Panama Canal provides a unique glimpse into the region's rich cultural heritage.
  • Metropolitan Nature Park: Escape the urban hustle at this expansive nature reserve, featuring diverse flora and fauna. Enjoy hiking trails that offer breathtaking views of the city and opportunities for birdwatching and picnicking in a serene environment.

Best time to go to Panama City

The best time to visit Panama City can depend on the weather and when visitor numbers rise and fall. The hottest average temperature in Panama City falls in April, when visitor numbers are average and weather is mostly sunny with light rain. The coolest average temperature in Panama City falls in November, visitor numbers are average and weather is mostly cloudy with frequent rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January78.8°F (26.0°C)No RainMostly SunnySlightly HighSlightly High
February79.2°F (26.2°C)No RainMostly SunnyAverageAverage
March79.7°F (26.5°C)No RainMostly SunnyAverageSlightly High
April80.4°F (26.9°C)Light RainMostly SunnyAverageAverage
May80.2°F (26.8°C)Frequent RainMostly CloudySlightly LowAverage
June79.9°F (26.6°C)Frequent RainMostly CloudyAverageAverage
July79.3°F (26.3°C)Frequent RainMostly CloudySlightly HighAverage
August79.2°F (26.2°C)Frequent RainMostly CloudyAverageAverage
September79.3°F (26.3°C)Frequent RainMostly CloudySlightly HighSlightly Low
October78.6°F (25.9°C)Frequent RainMostly CloudySlightly LowSlightly Low
November78.3°F (25.7°C)Frequent RainMostly CloudyAverageSlightly Low
December78.6°F (25.9°C)Light RainMostly CloudySlightly LowSlightly High

Tips to save on your trip to Panama City

  • Take advantage of package deals on Expedia and combine flights, hotels, or car rentals for a convenient and cost-effective trip to Panama City.
  • Consider traveling during the off-peak season (typically September to November) for more affordable package holidays to Panama City.
  • Use the Price per traveler filter on Expedia to find a package deal that suits your budget.
  • Check the VIP Access properties filter to discover outstanding hotels with added member perks at select properties.

Panama City Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
The price is ¥21,580 per night from Mar 3 to Mar 4
¥21,580
¥23,738 total
Mar 3 - Mar 4
includes taxes & fees
9/10 Wonderful! (4,918 reviews)
The breakfast

Reviewed on Feb 2, 2026

Hotel Riu Plaza Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
Fully refundableReserve now, pay when you stay
The price is ¥34,583 per night from Mar 7 to Mar 8
¥34,583
¥38,041 total
Mar 7 - Mar 8
includes taxes & fees
8.8/10 Excellent! (1,001 reviews)
Staff was super nice and room was great we also ate on the rooftop and food was great!

Reviewed on Feb 3, 2026

Waldorf Astoria Panama
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

4 out of 5
Via Espana 111 Panama City Panama
Fully refundableReserve now, pay when you stay
The price is ¥16,932 per night from Feb 8 to Feb 9
¥16,932
¥18,625 total
Feb 8 - Feb 9
includes taxes & fees
7.6/10 Good! (1,009 reviews)
All fantastic. We return year after year

Reviewed on Feb 2, 2026

Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Panama City

What to do in Panama City

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.