Panama Vacation Rentals

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Our top choices for Panama vacation rentals

StarLab '86 -Downtown Pet Friendly

StarLab '86 -Downtown Pet Friendly
Fort Smith
10.0 out of 10, Exceptional, (1)
"Everything that was advertised plus more. Very clean and the little surprises it had was amazing. "
United States
Clint S.
The price is ¥16,326
¥19,793 total
includes taxes & fees
Jan 4 - Jan 5, 2026
StarLab '86 -Downtown Pet Friendly

Charming 3-bedroom bungalow in delightful Fort Smith with WiFi, AC

Charming 3-bedroom bungalow in delightful Fort Smith with WiFi, AC
Fort Smith
9.8 out of 10, Exceptional, (24)
"Very quite beautiful space easy check in "
United States
Jalishia V.
The price is ¥11,662
¥27,503 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Charming 3-bedroom bungalow in delightful Fort Smith with WiFi, AC

Upscale home with high end furnishings and memory foam king bed. 2 car garage

Upscale home with high end furnishings and memory foam king bed. 2 car garage
2.0 star property
Spiro
7.4 out of 10, Good, (3)
"Beautiful, comfortable and in a quiet neighborhood. It was the perfect place to relax each evening after the wedding festivities that we were in town for. The living room is cozy and inviting, the beds are very comfortable and the bath towels are large and fluffy. If I’m ever in the area again I will definitely book again! Thank you"
United States
Sandi K.
The price is ¥15,394
¥27,850 total
includes taxes & fees
Dec 13 - Dec 14
Upscale home with high end furnishings and memory foam king bed. 2 car garage

Pirate Seeking crew. Downtown with hot tub!

Pirate Seeking crew. Downtown with hot tub!
fort smith
10.0 out of 10, Exceptional, (43)
"We arrr mighty pleased with all the nautical details. This inn be worth it's weight in doubloons, savvy?"
United States
Rory O.
The price is ¥16,353
¥19,826 total
includes taxes & fees
Dec 14 - Dec 15
Pirate Seeking crew. Downtown with hot tub!

Modern stone cottage just one minute from I-40 exit 321 in Muldrow, Oklahoma.

Modern stone cottage just one minute from I-40 exit 321 in Muldrow, Oklahoma.
Muldrow
8.0 out of 10, Very Good, (1)
"Our stay was wonderful, we had to go out and buy earing utensils but besides that everything was perfect."
United States
Resa H.
The price is ¥15,394
¥20,570 total
includes taxes & fees
Dec 20 - Dec 21
Modern stone cottage just one minute from I-40 exit 321 in Muldrow, Oklahoma.

The vampire's den, downtown big house, pets ok

The vampire's den, downtown big house, pets ok
Fort Smith
10.0 out of 10, Exceptional, (32)
"A fun time in a spook-tacular home. Thank you for having us in your home overnight. "
United States
Lisa S.
The price is ¥20,214
¥23,681 total
includes taxes & fees
Jan 5 - Jan 6, 2026
The vampire's den, downtown big house, pets ok

The Haven-Cute 3BR in Town

The Haven-Cute 3BR in Town
Fort Smith
9.8 out of 10, Exceptional, (29)
"We loved staying here and will rent again for our next trip"
United States
William M.
The Haven-Cute 3BR in Town

Spacious and charming 🌸🌸🌸

Spacious and charming 🌸🌸🌸
Fort Smith
9.4 out of 10, Exceptional, (14)
"Enjoyed the screened in porch and the friendly cats in the neighborhood. We loved the house and we will be back!"
United States
Anonymous traveler
The price is ¥11,914
¥24,249 total
includes taxes & fees
Dec 19 - Dec 20
Spacious and charming 🌸🌸🌸

My house your house

My house your house
Fort Smith
9.8 out of 10, Exceptional, (25)
"Very clean, very comfy and close to where we needed for the weekend."
United States
Cortney P.
The price is ¥18,970
¥40,992 total
includes taxes & fees
Jan 2 - Jan 3, 2026
My house your house

Cabin at Runestone Hideaway just steps from Heavener Runestone Park.

Cabin at Runestone Hideaway just steps from Heavener Runestone Park.
Heavener
10.0 out of 10, Exceptional, (47)
"Great place to stay for a nice little get away!"
United States
Heidi W.
Cabin at Runestone Hideaway just steps from Heavener Runestone Park.

Cabin in the Forest/Mountains

Cabin in the Forest/Mountains
Hackett
9.6 out of 10, Exceptional, (25)
"Quiet, peaceful and very clean. Enjoyed our stay. "
United States
Teena
Cabin in the Forest/Mountains

Southern Comfort Downtown Ft Smith!

Southern Comfort Downtown Ft Smith!
Fort Smith
10.0 out of 10, Exceptional, (30)
"Comfortable home away from home. "
United States
Monica P.
The price is ¥13,084
¥28,238 total
includes taxes & fees
Dec 14 - Dec 15
Southern Comfort Downtown Ft Smith!

Gretel ; Private one bedroom duplex in desirable Fort Smith downtown Park Hill

Gretel ; Private one bedroom duplex in desirable Fort Smith downtown Park Hill
Fort Smith
7.0 out of 10, Good, (2)
"This was a simple but nice accommodation. Owner was always available for communication even late. Very clean. Bed was comfortable and all necessities were available. Bathroom was small but adequate. Would absolutely stay here again."
United States
Jeremiah M.
The price is ¥11,184
¥34,981 total
includes taxes & fees
Dec 19 - Dec 20
Gretel ; Private one bedroom duplex in desirable Fort Smith downtown Park Hill

Amazing 3-bedroom home with 2 full baths. Spacious fenced backyard. WiFi present

Amazing 3-bedroom home with 2 full baths. Spacious fenced backyard. WiFi present
2.0 star property
Fort Smith
9.4 out of 10, Exceptional, (17)
"Great house to rent!! "
United States
Nancy M.
The price is ¥20,680
¥41,170 total
includes taxes & fees
Dec 15 - Dec 16
Amazing 3-bedroom home with 2 full baths. Spacious fenced backyard. WiFi present

DOWNTOWN COZY GETAWAY

DOWNTOWN COZY GETAWAY
Fort Smith
10.0 out of 10, Exceptional, (29)
"Loved the location, close to historical downtown, museums and places to eat. Easy access to everything we were interested in doing! We had a great time in Fort Smith and this cottage worked perfect for us and our sweet elderly dog! The house was just as pictured, so clean and well maintained. It had everything we needed and more. Cathy provided us with lots of information before our arrival and afterwards to make sure we were taken care of. We will definitely stay here again! "
United States
Paula O.
The price is ¥14,017
¥31,461 total
includes taxes & fees
Dec 14 - Dec 15
DOWNTOWN COZY GETAWAY

New Luxury 3 Bed 2 1/2 Bath Duplex

New Luxury 3 Bed 2 1/2 Bath Duplex
Barling
9.8 out of 10, Exceptional, (6)
"Great place had a good time "
United States
Casey M.
New Luxury 3 Bed 2 1/2 Bath Duplex

The Corner Cottage with Private Fishing Pond

The Corner Cottage with Private Fishing Pond
Roland
10.0 out of 10, Exceptional, (33)
"Really enjoyed the stay"
United States
greg d.
The Corner Cottage with Private Fishing Pond

Downtown Chop Shop house, HUGE garage pets allowed

Downtown Chop Shop house, HUGE garage pets allowed
fort smith
9.8 out of 10, Exceptional, (13)
"super clean and comfortable. host is bada## with communication. me and my crew love the chop house"
United States
randall m.
The price is ¥16,326
¥19,793 total
includes taxes & fees
Dec 14 - Dec 15
Downtown Chop Shop house, HUGE garage pets allowed

Brazil Retreat come relax in this beautiful spacious home.

Brazil Retreat come relax in this beautiful spacious home.
Fort Smith
9.6 out of 10, Exceptional, (13)
"Very nice place to stay very clean "
United States
Chaz
The price is ¥27,848
¥56,623 total
includes taxes & fees
Dec 16 - Dec 17
Brazil Retreat come relax in this beautiful spacious home.

Spacious Arkansas Abode w/ Balcony & Fire Pit!

Spacious Arkansas Abode w/ Balcony & Fire Pit!
3.0 star property
Fort Smith
10.0 out of 10, Exceptional, (2)
Spacious Arkansas Abode w/ Balcony & Fire Pit!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama Hotel Reviews

Find out more about Panama

Search for holiday rentals in Panama on Expedia! You can easily find your home rentals, villas, holiday apartments in Panama using one of the methods below:

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Look no further and take a look at our great range of rental properties in Panama!

Frequently asked questions

Can I find vacation rentals in Panama?

Yes, we offer vacation rentals close to well known attractions in Panama, or you can go with a more remote option if you're looking for a relaxing stay.

What's the top vacation rental that Panama has to offer?

StarLab '86 -Downtown Pet Friendly: This vacation home rental near Panama is located in the city center and has a patio, a garden, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. Kick off your shoes and enjoy yourself with a selection of games and a hot tub.

What’s there to see and do in Panama?

While you're exploring the area, Twyman Park and Davy Park are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Choctaw Travel Plaza and Casino and Spiro Mounds Archaeological Center.

What’s a vacation rental in Panama like?

A vacation rental is a private property you can stay in for a few weeks or just a few days in Panama. Vacation rentals offer extras like WiFi and washers and dryers so you'll feel just like you're staying in your own home. If you're concerned about a sanitized environment, a vacation rental can offer a sense of privacy away from public hotel elevators and busy concierge desks while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular option for a small group gathering.