Muscatine Vacations

Book a Hotel + Flight or Car together to unlock savings

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  • Plan, book, travel with confidence

  • Better together

    Save up to ¥45,448 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
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Find the Best Muscatine Vacation Packages

Muscatine Hotel Deals

Best Western Muscatine / Pearl City Hotel

Best Western Muscatine / Pearl City Hotel

2.5 out of 5
305 Cleveland St, Muscatine, IA
Fully refundableReserve now, pay when you stay
The price is ¥12,823 per night from Nov 16 to Nov 17
¥12,823
¥14,362 total
Nov 16 - Nov 17
includes taxes & fees
8.4/10 Very Good! (491 reviews)
Clean. Staff very friendly

Reviewed on Oct 26, 2025

Best Western Muscatine / Pearl City Hotel
AmericInn by Wyndham Muscatine

AmericInn by Wyndham Muscatine

2.5 out of 5
3115 Hwy 61 North, Muscatine, IA
Fully refundableReserve now, pay when you stay
The price is ¥12,351 per night from Nov 16 to Nov 17
¥12,351
¥13,833 total
Nov 16 - Nov 17
includes taxes & fees
7.4/10 Good! (417 reviews)
The room was clean. The jacuzzi tub was clean and easy to work.

Reviewed on Oct 4, 2025

AmericInn by Wyndham Muscatine
The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel

4 out of 5
119 Mississippi Drive West, Muscatine, IA
The price is ¥25,849 per night from Nov 14 to Nov 15
¥25,849
¥28,950 total
Nov 14 - Nov 15
includes taxes & fees
9.4/10 Exceptional! (274 reviews)
The river view is spectacular, the staff was excellent.

Reviewed on Sep 23, 2025

The Merrill Hotel, Muscatine, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.