The Best Resorts & Hotels with Spas in Mississippi Delta, MS from ￥11,627 in 2026 | Expedia

A harbor at sunset with fishing boats docked and their nets extended into the water.

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check availability on Mississippi Delta Resorts & Hotels with Spas

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Mississippi Delta hotels with a spa

A salon setting with two people seated, a table with various skincare products, a vase with flowers, and neatly rolled towels in the background.

A spacious lobby with a grand chandelier, a round seating area, and a second-floor balcony.

A restaurant with multiple dining areas, including booths and tables, with overhead lighting and a bar in the background.

A person sitting by a pool with clear blue water, wearing a white bikini and a large straw hat.

1. Harlow's Casino Resort & Spa

Greenville

Relax in riverside luxury with spa treatments featuring hot stone massages, aromatherapy, and deep-tissue therapies in spacious suites.

￥16,815

￥18,497 total

includes taxes & fees

Oct 4 - Oct 5

A reception area with a mosaic wall, wooden shelving, a reception desk, and a red chair.

A spacious lobby with a large chandelier, a central floral arrangement, and a geometric floor design.

A hotel room with a large bed, a sofa, a desk, and a TV.

A Starbucks Coffee with a counter, seating area, and display of beverages.

2. Horseshoe Tunica Hotel & Casino - A Caesars Rewards Destination

Robinsonville

￥7,895

￥11,627 total

includes taxes & fees

Oct 25 - Oct 26

A massage therapy room with two massage tables, a massage therapist, and a client receiving a back massage.

A spacious lobby with a curved ceiling, large columns, and potted plants.

A casino area with multiple slot machines, escalators, and a carpeted floor.

A spacious lobby with a polished marble floor, a curved ceiling, and a reception desk.

3. Gold Strike Casino Resort

Robinsonville

Experience rejuvenating massages at this tranquil resort with a full-service spa, just moments from Gold Strike Casino's excitement.

￥12,321

￥16,160 total

includes taxes & fees

Nov 2 - Nov 3

A living room with a chandelier, two sofas, a coffee table, and a fireplace.

A modern bar area with a long counter, multiple stools, and a variety of glassware and bottles on shelves.

A covered porch with outdoor seating, a view of the landscape, and a railing.

A stone fountain with water spouting into a pool, surrounded by brick walls and greenery.

4. The Inn at Cedar Grove

Vicksburg

Rejuvenate with deep-tissue massages at this historic inn with a serene garden and seasonal outdoor pool near Vicksburg's attractions.

￥21,682

￥23,851 total

includes taxes & fees

Oct 11 - Oct 12

View all properties

Choose what matters most at spa hotels in Mississippi Delta

Pool

Breakfast included

Hot tub

4 stars

5 stars

Top Mississippi Delta Hotel Reviews

Harlow's Casino Resort & Spa

Harlow's Casino Resort & Spa

10/10 Excellent

"I loved the everything about this place"

Drury Inn & Suites Memphis Southaven

Drury Inn & Suites Memphis Southaven

10/10 Excellent

"Perfect hotel. Oh, there was some airport noise for a few minutes but that passed. Breakfast and the early evening food was wonderful. The desk clerk went out of her way to make us feel welcome and take care of everything. The bartender could be a stand-up comedian and really helped everyone feel welcome. I would stay here again anytime."

Explore a world of travel with Expedia

Book Resorts & Hotels with Spas in Mississippi Delta on Expedia.com