Mesopotamia Vacations from ¥400,512

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The Latest Mesopotamia Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Principado Downtown

Principado Downtown

El Centro
¥400,512
per person
Dec 5 - Dec 11
found 1 day ago
Roundtrip flight included
Bangkok (BKK) to Buenos Aires (EZE)
9/10 Wonderful! (1,002 reviews)
Staff was friendly. Room was clean. Breakfast was nice. Outside environment is perfect with shops and restaurants in close proximity.

Reviewed on Sep 28, 2026

Palacio Duhau - Park Hyatt Buenos Aires

Palacio Duhau - Park Hyatt Buenos Aires

Recoleta
¥663,656
per person
Dec 5 - Dec 11
found 1 day ago
Roundtrip flight included
Bangkok (BKK) to Buenos Aires (EZE)
9.4/10 Exceptional! (520 reviews)
El hotel , en muy buen estado , limpio , el personal , en su mayoría amable , algunos empleados en el counter de recepción no muy capacitados para poder responder educadamente o con tino . En los restaurantes nesecitas un poco más de personal , ya que no se dan abasto cuando están casi al 100% ,regresaría sin duda alguna .

Reviewed on Sep 17, 2026

Bulnes Eco Suites

Bulnes Eco Suites

Palermo
¥404,442
per person
Dec 5 - Dec 11
found 1 day ago
Roundtrip flight included
Bangkok (BKK) to Buenos Aires (EZE)
9.4/10 Exceptional! (1,290 reviews)
This guy lave is conveniently located in near Palermo shops , subway is steps away , very clean and smooth check in , highly recommended

Reviewed on Sep 27, 2026

Loi Suites Recoleta Hotel

Loi Suites Recoleta Hotel

Recoleta
¥438,940
per person
Dec 5 - Dec 11
found 1 day ago
Roundtrip flight included
Bangkok (BKK) to Buenos Aires (EZE)
9.2/10 Wonderful! (864 reviews)
Really liked the hotel with some caveats. The staff is very friendly, the lobby and restaurant area are quite nice and large and location is great. The rooms are large yet very bland in the sense they are overly white and barely decorated. The bathroom was uncomfortable and after showering everything was wet and it smelled of dampness for the rest of the day. Another thing I disliked were the fluorescent, bright lights in the hallways. The light flooded into the room. That's a really easy fix that can make the ambience warmer.

Reviewed on Sep 20, 2026

1828 Smart Hotel

1828 Smart Hotel

Palermo
¥448,146
per person
Dec 5 - Dec 11
found 1 day ago
Roundtrip flight included
Bangkok (BKK) to Buenos Aires (EZE)
9.4/10 Exceptional! (730 reviews)
Really nice hotel in a great location with fantastic staff. They are all very friendly and accommodating. The hotel needs a bit of a refresh though

Reviewed on Sep 24, 2026

Find the Best Mesopotamia Vacation Packages

Mesopotamia Hotel Deals

Marriott Corrientes Hotel

Marriott Corrientes Hotel

Av Costanera Juan Pablo II y Lavalle Corrientes
Fully refundableReserve now, pay when you stay
¥22,491
¥22,491 total
Oct 5 - Oct 6
9.8/10 Exceptional! (47 reviews)
"Impecable"

Reviewed on Sep 2, 2026

Marriott Corrientes Hotel
Costarenas Hotel & Spa

Costarenas Hotel & Spa

12 de Abril y Quiros Colon Entre Rios
Fully refundableReserve now, pay when you stay
¥17,694
¥17,694 total
Oct 9 - Oct 10
8.8/10 Excellent! (64 reviews)
"Estaba todo muy lindo"

Reviewed on Jun 8, 2026

Costarenas Hotel & Spa
O2 Hotel Gualeguaychú

O2 Hotel Gualeguaychú

115 3 de Febrero Gualeguaychú Entre Ríos
Fully refundableReserve now, pay when you stay
¥5,348
¥5,348 total
Sep 29 - Sep 30
O2 Hotel Gualeguaychú
See all 523 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Mesopotamia attractions

A dirt path through a dense palm tree forest.

El Palmar National Park

8.0/10 (2 reviews)
Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay.
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A large church with a prominent dome and two bell towers.

Basilica Nuestra Senora De Itati

Learn about the local history of Municipo de Itatí when you take a trip to Basilica Nuestra Senora De Itati.
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A stone pergola with steps leading up to it, surrounded by greenery and a clear sky.

Costanera de Corrientes

9.0/10 (4 reviews)
Enjoy an outing to Costanera de Corrientes during your stay in Corrientes. You can enjoy the restaurants while in the area.
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Termas de Federacion

10.0/10 (2 reviews)
Bring your family to Termas de Federacion and have a fun-filled day at this amusement park in Federacion. Stroll along the beaches or discover the area's waterfalls.
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Portal Carambola

You can take time to visit Portal Carambola during your travels to Concepción. While you're in the area, wander around the parks.
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Concepción del Uruguay City Racetrack

You can take time to visit Concepción del Uruguay City Racetrack during your travels to Concepción del Uruguay. Experience the area's art scene and museums.
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Termas Concepcion Entrerios

Bring your family to Termas Concepcion Entrerios and enjoy the excitement of this amusement park in Concepción del Uruguay. Experience the area's art scene and museums.
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Victoria Beach

If a restful vacation is part of your travel plans, Victoria Beach might be the perfect place to seek out during your trip to Victoria. Make some time to visit the monuments while you're in the area.
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Frequently asked questions

How much does a Mesopotamia vacation package cost?
Maybe less than you might think — from only ¥400,512, actually! By combining hotels, flights and car rentals into your own tailor-made package, your Mesopotamia escape is just a few clicks away.
How do I get a cheap travel package to Mesopotamia?
Crafting your own Mesopotamia vacation package with Expedia is a great way to save. We offer more than 550 partner airlines and 1,000,000 hotels across the globe. With such a broad range to choose from, you'll have no worries creating your next dream adventure.
What are the top hotels in Mesopotamia?
Costarenas Hotel & Spa and Hotel Queguay know how to make their guests feel welcome in Colon. If your itinerary also includes Parana, check out Mayim Hotel Termal & Spa and Costarenas Hotel & Spa. Both are very popular with travelers.
How far in advance should I book my Mesopotamia vacation?
It all depends on the airline, but you can usually compare international fares on Expedia nearly a year in advance. While it's generally a good idea to book ahead of time, lucky travelers occasionally nab a cheaper ticket just weeks before departure dates.
What does an Expedia Mesopotamia travel package include?
You can choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can add the fun stuff like experiences and activities. Want to pick your fare class? That's also easy to do. The choice is all yours when it comes to arranging your perfect Mesopotamia trip.
What should I know before booking a Mesopotamia travel package?
Booking all the parts of your getaway together is a smart way to save. Bundle your flights, car rentals and hotels into a convenient package. But it's not just hotels. Expedia has all types of properties, including vacation rentals such as mountain cabins and serviced residences. The list is almost endless!
Can I choose my airline with a Mesopotamia Expedia vacation package?
Yes, and with over 550 airlines to select from worldwide, you're not short on choice. Search the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Mesopotamia vacation package?
Don't worry if you're rethinking your Mesopotamia vacation package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We realize life can throw the occasional spanner in the works, so head to our Customer Service Portal if that occurs. When you're ready to make changes, we'll take care of it.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.