Mesopotamia Vacations from ￥269,152
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The Latest Mesopotamia Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Krista Boutique Hotel
Palermo
￥286,600
per person
Nov 14 - Nov 16
found 15 hours ago
Roundtrip flight included
Tokyo (TYO) to Buenos Aires (EZE)
9.2/10 Wonderful! (372 reviews)
La atención fue de lo mejor y la ubicación es privilegiada. Habitacion excepcional, con el
único detalle es que las housekeepers deben de cambiar o bien doblar las toallas cuando esto lo amerita, por lo demás espectacular 💯✅
Reviewed on Aug 22, 2026
Palladio Hotel Buenos Aires - MGallery Collection
Recoleta
￥335,556
per person
Nov 14 - Nov 16
found 15 hours ago
Roundtrip flight included
Tokyo (TYO) to Buenos Aires (EZE)
9.8/10 Exceptional! (782 reviews)
Hotel is in an excellent location. You can walk to most sights and areas in under 30 minutes. We felt very safe walking during the day and the only night we walked to a restaurant we went down a main street and then down the main theatre street and both were very bust and felt safe. Our room was twin queen beds with a balcony overlooking the small park. It was huge. It had so much wardrobe, drawer and luggage space you could forget where you had stored things. Water was replenished twice a day. There was a fridge and a Nespresso machine as well as a kettle. There were slippers and robes. The hotel was very quiet at night. The breakfast was good not amazing. The staff were all lovely and service was brilliant. The bed, room and bathroom were spotlessly clean. I would stay hete again in a heartbeat.
Reviewed on Sep 2, 2026
Find the Best Mesopotamia Vacation Packages
Mesopotamia Hotel Deals
Marriott Corrientes Hotel
Av Costanera Juan Pablo II y Lavalle Corrientes
Fully refundableReserve now, pay when you stay
￥21,468
￥21,468 total
Sep 13 - Sep 14
9.8/10 Exceptional! (45 reviews)
"Impecable"
Reviewed on Sep 2, 2026
O2 Hotel Gualeguaychú
115 3 de Febrero Gualeguaychú Entre Ríos
Fully refundableReserve now, pay when you stay
￥5,803
￥5,803 total
Sep 3 - Sep 4
7.8/10 Good! (93 reviews)
"Hola,todos los chicos con excelente atencion,muy dispuestos y nos hicieron muy buenas recomendaciones,si tuviera que opinar al fuera de lo expresado,es el servicio de desayuno,muy muy muy básico,2 medialunas chicas " peladas " y 3 tostadas y bien tostadas,sería agradable pongan alguna otra cosita ..."
Reviewed on Aug 30, 2026
Hathor Concordia
Ruta Nacional 14-km 264.5 Concordia Entre Rios
￥9,802
￥11,564 total
Sep 3 - Sep 4
8.8/10 Excellent! (389 reviews)
"AC did not work well, food was OK. Staff friendly. Good hotel for a stay on the road."
Reviewed on Dec 22, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Mesopotamia attractions
El Palmar National Park
8.0/10 (2 reviews)
Explore the great outdoors at El Palmar National Park, a lovely green space in Ubajay.
Basilica Nuestra Senora De Itati
Learn about the local history of Municipo de Itatí when you take a trip to Basilica Nuestra Senora De Itati.
Costanera de Corrientes
9.0/10 (4 reviews)
Enjoy an outing to Costanera de Corrientes during your stay in Corrientes. You can enjoy the restaurants while in the area.
Termas de Federacion
10.0/10 (2 reviews)
Bring your family to Termas de Federacion and have a fun-filled day at this amusement park in Federacion. Stroll along the beaches or discover the area's waterfalls.
Concepción del Uruguay City Racetrack
You can take time to visit Concepción del Uruguay City Racetrack during your travels to Concepción del Uruguay. Experience the area's art scene and museums.
Victoria Beach
If a restful vacation is part of your travel plans, Victoria Beach might be the perfect place to seek out during your trip to Victoria. Make some time to visit the monuments while you're in the area.
Portal Carambola
You can take time to visit Portal Carambola during your travels to Concepción. While you're in the area, wander around the parks.
Termas Concepcion Entrerios
Bring your family to Termas Concepcion Entrerios and enjoy the excitement of this amusement park in Concepción del Uruguay. Experience the area's art scene and museums.
Frequently asked questions
How much does a Mesopotamia vacation package cost?
Maybe less than you might think — from only ￥269,152, actually! By combining hotels, flights and car rentals into your own tailor-made package, your Mesopotamia escape is just a few clicks away.
How do I get a cheap travel package to Mesopotamia?
Crafting your own Mesopotamia vacation package with Expedia is a great way to save. We offer more than 550 partner airlines and 1,000,000 hotels across the globe. With such a broad range to choose from, you'll have no worries creating your next dream adventure.
What are the top hotels in Mesopotamia?
Costarenas Hotel & Spa and Hotel Queguay know how to make their guests feel welcome in Colon. If your itinerary also includes Parana, check out Mayim Hotel Termal & Spa and Costarenas Hotel & Spa. Both are very popular with travelers.
How far in advance should I book my Mesopotamia vacation?
It all depends on the airline, but you can usually compare international fares on Expedia nearly a year in advance. While it's generally a good idea to book ahead of time, lucky travelers occasionally nab a cheaper ticket just weeks before departure dates.
What does an Expedia Mesopotamia travel package include?
You can choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can add the fun stuff like experiences and activities. Want to pick your fare class? That's also easy to do. The choice is all yours when it comes to arranging your perfect Mesopotamia trip.
What should I know before booking a Mesopotamia travel package?
Booking all the parts of your getaway together is a smart way to save. Bundle your flights, car rentals and hotels into a convenient package. But it's not just hotels. Expedia has all types of properties, including vacation rentals such as mountain cabins and serviced residences. The list is almost endless!
Can I choose my airline with a Mesopotamia Expedia vacation package?
Yes, and with over 550 airlines to select from worldwide, you're not short on choice. Search the available options and find out which airline fits your budget and needs.
If I'm not able to travel, can I cancel my Mesopotamia vacation package?
Don't worry if you're rethinking your Mesopotamia vacation package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it for free. However, bookings made more than 24 hours ago may incur fees from your hotel, airline or car rental company. We realize life can throw the occasional spanner in the works, so head to our Customer Service Portal if that occurs. When you're ready to make changes, we'll take care of it.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
