Mesopotamia Vacations from ￥278,993

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The Latest Mesopotamia Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Regente Palace Hotel

Regente Palace Hotel

4 out of 5
El Centro
Price was ￥341,293, price is now ￥278,993 per person
￥278,993
per person
Jul 17 - Jul 20
found 6 hours ago
Roundtrip flight included
Tokyo (TYO) to Buenos Aires (EZE)
7.6/10 Good! (411 reviews)
Breakfast was good. The reception area staff is very nice and hospitable. Pedro is excellent!

Reviewed on Jun 11, 2026

Estancia Villa Maria

Estancia Villa Maria

4 out of 5
Price was ￥424,706, price is now ￥305,872 per person
￥305,872
per person
Jul 17 - Jul 20
found 21 hours ago
Roundtrip flight included
Tokyo (TYO) to Buenos Aires (EZE)
9.4/10 Exceptional! (110 reviews)
A fairytale stay! The staff was incredible and kind, the property was stunning and the asado incredible. If you are going to Buenos Aires, this is a MUST stay location.

Reviewed on May 11, 2026

Bulnes Eco Suites

Bulnes Eco Suites

4 out of 5
Palermo
Price was ￥358,460, price is now ￥286,703 per person
￥286,703
per person
Jul 17 - Jul 20
found 21 hours ago
Roundtrip flight included
Tokyo (TYO) to Buenos Aires (EZE)
9.4/10 Exceptional! (1,249 reviews)
Everything is good. Excellent location. I always come back

Reviewed on Jun 12, 2026

Krista Boutique Hotel

Krista Boutique Hotel

4 out of 5
Palermo
Price was ￥377,947, price is now ￥303,058 per person
￥303,058
per person
Jul 17 - Jul 20
found 21 hours ago
Roundtrip flight included
Tokyo (TYO) to Buenos Aires (EZE)
9.2/10 Wonderful! (359 reviews)
Great property and location. Rooms spacious and well appointed. Staff is superb

Reviewed on May 6, 2026

Casa Lucia Member of Melia Collection

Casa Lucia Member of Melia Collection

5 out of 5
El Centro
Price was ￥396,209, price is now ￥322,965 per person
￥322,965
per person
Jul 17 - Jul 20
found 21 hours ago
Roundtrip flight included
Tokyo (TYO) to Buenos Aires (EZE)
9.6/10 Exceptional! (165 reviews)
It’s a beautiful place to enjoy. The property is magnificent, perfectly located to get any corner of Buenos Aires, and very clean as well. The staff were incredibly nice and helpful. The parking service is excellent, someone is always available to get your car ready when it was needed .

Reviewed on Jun 8, 2026

Find the Best Mesopotamia Vacation Packages

Mesopotamia Hotel Deals

Marriott Corrientes Hotel

Marriott Corrientes Hotel

4.5 out of 5
Av Costanera Juan Pablo II y Lavalle Corrientes
Fully refundableReserve now, pay when you stay
The price is ￥18,624 per night from Jun 20 to Jun 21
￥18,624
￥18,624 total
Jun 20 - Jun 21
10/10 Exceptional! (37 reviews)
"Me da mucho gusto que Corrientes tenga un hotel de esta categoría. El personal es excelente, desde el front desk hasta las personas de mantenimiento. Cuando supieron que íbamos a casarnos nos enviaron una bandeja de refreshments con una hermosa tarjeta de felicitación. La presión y temperatura de ..."

Reviewed on Jun 6, 2026

Marriott Corrientes Hotel
Turismo Hotel Casino

Turismo Hotel Casino

2.5 out of 5
650 Entre Ríos Corrientes Corrientes
Fully refundableReserve now, pay when you stay
The price is ￥15,490 per night from Jun 22 to Jun 23
￥15,490
￥15,490 total
Jun 22 - Jun 23
9/10 Wonderful! (7 reviews)
"The best place to stay in Corrientes! Amazing views"

Reviewed on Apr 7, 2026

Turismo Hotel Casino
Costarenas Hotel & Spa

Costarenas Hotel & Spa

3.5 out of 5
12 de Abril y Quiros Colon Entre Rios
Fully refundableReserve now, pay when you stay
The price is ￥18,433 per night from Jun 17 to Jun 18
￥18,433
￥18,433 total
Jun 17 - Jun 18
8.8/10 Excellent! (64 reviews)
"Estaba todo muy lindo"

Reviewed on Jun 8, 2026

Costarenas Hotel & Spa
See all 524 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Mesopotamia attractions

Parroquia Nuestra Señora de Itati

Basilica Nuestra Senora De Itati

Learn about the local history of Municipo de Itatí when you take a trip to Basilica Nuestra Senora De Itati.
See properties

Frequently asked questions

Can I cancel my flight booking to Mesopotamia due to COVID-19?
If you haven't booked yet, glance over the terms and conditions of the airline you're considering. If you've already reserved your flight to Mesopotamia, make use of our Customer Service Portal. It will help determine which COVID-19 policies apply to your booking and provide advice on the next steps.
What's the best way to find cheap flights to Mesopotamia that have flexible change policies?
Search for your bargain flights to Mesopotamia, then tick the "No change fee" box directly underneath the "Flexible change policies" heading. It's that easy. We know that plans change and flexibility is essential, so you can book with confidence with Expedia.
What are some of the general tips for travelers to Mesopotamia during the COVID-19 outbreak?
If it's your first time traveling during the COVID-19 pandemic, you'll notice a range of new rules and restrictions in place. Take note of these tips and make your escape to Mesopotamia a smooth one:
  • Research if any travel restrictions apply to your destination and origin before booking. Also check if there are any requirements you'll have to follow on arrival, such as health testing.
  • Keep your face mask on even during airport screening. A TSA employee will require you to lower your mask temporarily to verify your identity.
  • Instead of handing a TSA employee your boarding pass, position it directly on the scanner yourself. When that's done, hold it up for inspection.
  • You're permitted to take one container of hand sanitizer up to 12 oz (350 ml) in your hand luggage. This will need to be taken out for screening.
  • Place any personal items (phone, wallet and keys for example) in your carry-on rather than a bin to minimize handling during screening.
  • Separate any food you have for screening. Food items often set off the alarm. Placing them in a clear plastic bag and into a bin reduces the need for a TSA employee to handle and inspect your belongings.

Which airlines fly to Mesopotamia?
Book your ticket with LATAM Airlines and then start putting together your Mesopotamia travel itinerary. This top airline provides 143 flights each month to Ministro Pistarini Intl. Airport (EZE), a major gateway.
How can I find cheap tickets to Mesopotamia?
One of the easiest ways to snare cheap tickets to Mesopotamia is to be flexible with your dates. Search for your flights, then click "flexible dates" above the results. It will bring up the cheapest prices for nearby days. The lowest price for a flight to Mesopotamia in the last seven days was . Booking ahead will generally help you get an even better deal.
How much is a flight to Mesopotamia?
You could have scored a return ticket to Mesopotamia from anywhere between and in the last seven days. For one-way trips leaving from (), the lowest amount paid during this period was just .
What are the most popular airports to fly into in Mesopotamia?
Book your flight to Ministro Pistarini Intl. Airport (EZE) and sample all that Mesopotamia has to offer. As the region's main entry point, around 850 flights land here each month.
When is the cheapest time to fly to Mesopotamia?
Leave for Mesopotamia early on in the week and you'll usually be rewarded more economical fares. Tuesday is typically the cheapest day to get on a plane, followed closely by Monday. If you'd like to avoid the most expensive flights, keep clear of Saturdays.
How much is a plane ticket to Mesopotamia?
Seats to Mesopotamia ranged from to in the last seven days. Normally, the earlier you make a reservation, the better the deal.
Which airlines with flights to Mesopotamia employ COVID-19 cleanliness policies?
In response to the global COVID-19 pandemic, airlines have adopted new precautionary measures to help their passengers and crew get back in the air. Here are some good examples:
  • Aerolineas Argentinas - this airline is known for conducting passenger temperature checks and cleaning with disinfectant.
  • LATAM Airlines - this airline is known for providing passenger masks and capped capacity flights.
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.