Mesopotamia Vacations from ￥212,930

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ￥45,448 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

The Latest Mesopotamia Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Regal Pacific Buenos Aires

Regal Pacific Buenos Aires

4.5 out of 5
Microcentro
Price was ￥278,686, price is now ￥212,930 per person
￥212,930
per person
Jan 25 - Jan 29
found 1 day ago
Roundtrip flight included
Tokyo (HND) to Buenos Aires (EZE)
8.8/10 Excellent! (1,005 reviews)
This is an excellent hotel in Buenos Aires "Microcentro". Good hotel and close by walking distance to Buenos Aires main attractions. Good place to stay also for business purposes.

Reviewed on Aug 23, 2025

Estancia Villa Maria

Estancia Villa Maria

3.5 out of 5
Price was ￥671,430, price is now ￥476,820 per person
￥476,820
per person
Dec 29 - Jan 2
found 20 hours ago
Roundtrip flight included
Tokyo (TYO) to Buenos Aires (EZE)
9.4/10 Exceptional! (97 reviews)
We had an incredible stay. It was very relaxing. The staff is exceptional. The villa itself is very charming. It’s about 45 minutes from the city we had a car and would spend the day in the city and come back in the afternoon for a peaceful break.

Reviewed on Aug 6, 2025

Faena Hotel Buenos Aires

Faena Hotel Buenos Aires

5 out of 5
Puerto Madero
Price was ￥379,916, price is now ￥282,907 per person
￥282,907
per person
Jan 25 - Jan 29
found 1 day ago
Roundtrip flight included
Tokyo (HND) to Buenos Aires (EZE)
9/10 Wonderful! (457 reviews)
Good property. I was thinking more of it like the Faena in Miami FL. The windows in this hotel are very thin. You hear everything outside, cars driving, cars racing, car mufflers. Overall a good experience.

Reviewed on Sep 1, 2025

Hospedaje La Rana

Hospedaje La Rana

2 out of 5
Comuna 7
Save 100% on your flight
Price was ￥27,726,874, price is now ￥20,940,496 per person
￥20,940,496
per person
Jan 25 - Jan 29
found 8 hours ago
Roundtrip flight included
Tokyo (TYO) to Buenos Aires (EZE)
No reviews
Casa Lucia Member of Melia Collection

Casa Lucia Member of Melia Collection

5 out of 5
Retiro
Price was ￥339,444, price is now ￥261,416 per person
￥261,416
per person
Jan 25 - Jan 29
found 8 hours ago
Roundtrip flight included
Tokyo (TYO) to Buenos Aires (EZE)
9.6/10 Exceptional! (55 reviews)
1st Class property situated in quiet urban neighborhood near center of Old Town. Easy walking distance to Casa Rosada, Cathedral, Obelisk, Peatonal Florida (mile-long pedestiran mall) (lees than 1.5 km). Excellent onsite restaurant, lounge-bar, parking garage. Cannot recommend highly enough.

Reviewed on Nov 3, 2025

Find the Best Mesopotamia Vacation Packages

Mesopotamia Hotel Deals

Marriott Corrientes Hotel

Marriott Corrientes Hotel

4.5 out of 5
Av Costanera Juan Pablo II y Lavalle, Corrientes
Fully refundableReserve now, pay when you stay
The price is ￥19,263 per night from Dec 5 to Dec 6
￥19,263
￥19,263 total
Dec 5 - Dec 6
Marriott Corrientes Hotel
O2 Hotel Gualeguaychú

O2 Hotel Gualeguaychú

2.5 out of 5
115 3 de Febrero, Gualeguaychú, Entre Ríos
Fully refundableReserve now, pay when you stay
The price is ￥5,353 per night from Nov 25 to Nov 26
￥5,353
￥5,353 total
Nov 25 - Nov 26
7.6/10 Good! (63 reviews)
Hotel is very comfortable and clean. There is no breakfast or hotel parking, and the wifi does not work properly in most floors and rooms. Other than that, the staff is very friendly and nice.

Reviewed on Jan 2, 2025

O2 Hotel Gualeguaychú
Hathor Concordia

Hathor Concordia

3 out of 5
Ruta Nacional 14-km 264.5, Concordia, Entre Rios
8.6/10 Excellent! (352 reviews)
Very clean room at affordable price. The dinning is of excellent quality at very reasonable price. The staff are quite friendly and helpful.

Reviewed on Dec 31, 2024

Get rates
Hathor Concordia
See all 495 properties in Mesopotamia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

Can I cancel my flight booking to Mesopotamia due to COVID-19?
If you haven't booked yet, glance over the terms and conditions of the airline you're considering. If you've already reserved your flight to Mesopotamia, make use of our Customer Service Portal. It will help determine which COVID-19 policies apply to your booking and provide advice on the next steps.
What's the best way to find cheap flights to Mesopotamia that have flexible change policies?
Search for your bargain flights to Mesopotamia, then tick the "No change fee" box directly underneath the "Flexible change policies" heading. It's that easy. We know that plans change and flexibility is essential, so you can book with confidence with Expedia.
What are some of the general tips for travelers to Mesopotamia during the COVID-19 outbreak?
If it's your first time traveling during the COVID-19 pandemic, you'll notice a range of new rules and restrictions in place. Take note of these tips and make your escape to Mesopotamia a smooth one:
  • Research if any travel restrictions apply to your destination and origin before booking. Also check if there are any requirements you'll have to follow on arrival, such as health testing.
  • Keep your face mask on even during airport screening. A TSA employee will require you to lower your mask temporarily to verify your identity.
  • Instead of handing a TSA employee your boarding pass, position it directly on the scanner yourself. When that's done, hold it up for inspection.
  • You're permitted to take one container of hand sanitizer up to 12 oz (350 ml) in your hand luggage. This will need to be taken out for screening.
  • Place any personal items (phone, wallet and keys for example) in your carry-on rather than a bin to minimize handling during screening.
  • Separate any food you have for screening. Food items often set off the alarm. Placing them in a clear plastic bag and into a bin reduces the need for a TSA employee to handle and inspect your belongings.

Which airlines fly to Mesopotamia?
Book your ticket with LATAM Airlines and then start putting together your Mesopotamia travel itinerary. This top airline provides 143 flights each month to Ministro Pistarini Intl. Airport (EZE), a major gateway.
How can I find cheap tickets to Mesopotamia?
One of the easiest ways to snare cheap tickets to Mesopotamia is to be flexible with your dates. Search for your flights, then click "flexible dates" above the results. It will bring up the cheapest prices for nearby days. The lowest price for a flight to Mesopotamia in the last seven days was . Booking ahead will generally help you get an even better deal.
How much is a flight to Mesopotamia?
You could have scored a return ticket to Mesopotamia from anywhere between and in the last seven days. For one-way trips leaving from (), the lowest amount paid during this period was just .
What are the most popular airports to fly into in Mesopotamia?
Book your flight to Ministro Pistarini Intl. Airport (EZE) and sample all that Mesopotamia has to offer. As the region's main entry point, around 850 flights land here each month.
When is the cheapest time to fly to Mesopotamia?
Leave for Mesopotamia early on in the week and you'll usually be rewarded more economical fares. Tuesday is typically the cheapest day to get on a plane, followed closely by Monday. If you'd like to avoid the most expensive flights, keep clear of Saturdays.
How much is a plane ticket to Mesopotamia?
Seats to Mesopotamia ranged from to in the last seven days. Normally, the earlier you make a reservation, the better the deal.
Which airlines with flights to Mesopotamia employ COVID-19 cleanliness policies?
In response to the global COVID-19 pandemic, airlines have adopted new precautionary measures to help their passengers and crew get back in the air. Here are some good examples:
  • Aerolineas Argentinas - this airline is known for conducting passenger temperature checks and cleaning with disinfectant.
  • LATAM Airlines - this airline is known for providing passenger masks and capped capacity flights.
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.