Find hotels near Mayo Clinic Florida, Jacksonville from ¥16,891

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Our top choices for Mayo Clinic Florida hotels

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (501 reviews)
"Breakfast was ok nothing special but the staff were all helpful and upbeat. Would highly recommend this property especially if you’re going to Mayo Clinic."
United States
JOHN
The price is ¥21,127
¥23,978 total
includes taxes & fees
Jun 7 - Jun 8
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (220 reviews)
"Property was very clean and convenient for access to Mayo Clinic."
United States
Paul
The price is ¥25,508
¥28,951 total
includes taxes & fees
May 15 - May 16
Hilton Jacksonville At Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,006 reviews)
"Close to Mayo Clinic and the Beach area "
United States
Kert
The price is ¥17,819
¥20,225 total
includes taxes & fees
Jun 7 - Jun 8
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
2.6 km from Mayo Clinic Florida
8.8 out of 10, Excellent, (1,005 reviews)
"It was convenient to Mayo Clinic. Good breakfast and clean room."
United States
Michelle
The price is ¥14,882
¥16,891 total
includes taxes & fees
Jun 7 - Jun 8
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.4 km from Mayo Clinic Florida
8.4 out of 10, Very Good, (772 reviews)
"Location across from Mayo is ideal."
United States
Peter
The price is ¥25,168
¥28,566 total
includes taxes & fees
Jun 6 - Jun 7
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
2.5 star property
Deerwood, 8 km from Mayo Clinic Florida
10.0 out of 10, Exceptional, (12 reviews)
"Clean room, friendly staff"
United States
Despina
The price is ¥18,469
¥20,963 total
includes taxes & fees
Jun 1 - Jun 2
Hyatt Studios Jacksonville/St Johns Town Center

Element Jacksonville Beach

Element Jacksonville Beach
3.0 star property
5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (554 reviews)
"Excellent breakfast. Cleanest rooms I've experienced. 5 🌟's"
United States
Don
The price is ¥23,761
¥26,969 total
includes taxes & fees
May 31 - Jun 1
Element Jacksonville Beach

The Hotel Palms Poolside

The Hotel Palms Poolside
2.5 star property
7.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (471 reviews)
"Cute updated quintessential Florida motel. Location was great and owner was super friendly. Looking forward to the next visit and merger with the palms. "
United States
Tara
The price is ¥28,230
¥32,041 total
includes taxes & fees
Jun 7 - Jun 8
The Hotel Palms Poolside

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,006 reviews)
"Great place. Not too far from beach and not too far from Mayo clinic! "
United States
Randy
The price is ¥19,071
¥21,646 total
includes taxes & fees
Jun 7 - Jun 8
Holiday Inn Express Jacksonville Beach by IHG

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
4.2 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,090 reviews)
"Friendly staff- very convenient for Mayo Hospital Apts."
United States
Marcia
The price is ¥21,127
¥23,979 total
includes taxes & fees
May 25 - May 26
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

The Hotel Palms Courtyard

The Hotel Palms Courtyard
3.5 star property
7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (297 reviews)
"Very cute updated 60’s-vibe motel. Perfect for our short stay in the Jacksonville beach area. We checked in on our own, with no problems. (Clear instructions emailed the day before.) The room Was clean, amenities nice, comfortable bed with lots of pillows. We did not have housekeeping, but technically really didn’t need. There was a coffee shop on premises, which is apparently popular with local runners after their beach run, and because our room was upfront across from the shop, we had about...
United States
Jill
The price is ¥28,725
¥32,603 total
includes taxes & fees
Jun 7 - Jun 8
The Hotel Palms Courtyard

Ponte Vedra Inn & Club

Ponte Vedra Inn & Club
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (822 reviews)
"The Lodge at Ponte Vedra is truly exceptional. The staff goes above and beyond to make you feel welcome and cared for. The accommodations are elegant, comfortable, and immaculately maintained. Every detail—from the beautiful ocean views to the outstanding amenities—makes for a luxurious and relaxing experience. An unforgettable stay, and I can’t wait to return."
United States
James
The price is ¥85,820
¥100,222 total
includes taxes & fees
Jun 7 - Jun 8
Ponte Vedra Inn & Club

The Lodge and Club at Ponte Vedra Beach

The Lodge and Club at Ponte Vedra Beach
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (693 reviews)
"Fantastic stay at The Ponte Vedra Lodge and Club!!! This hotel met and exceeded my expectations, especially in regard to my clean and spacious room, which was convenient to both the pool and beach!!"
United States
Tracey
The price is ¥70,188
¥82,792 total
includes taxes & fees
Jun 7 - Jun 8
The Lodge and Club at Ponte Vedra Beach

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3,930 reviews)
"I have to be seen at Mayo Clinic every year and I found that this hotel is perfect. It’s a short drive to Mayo and the hotel is clean, has a large comfortable lounge, restaurant, and a cafe where you can get pizza, sodas etc and misc items. I found that the shower floor to be extremely slippery and worse when the liquid soap coated the basin. The employees from the front desk to housekeeping were very polite and helpful to make your stay relaxing and you have to love the sound of the waves...
United States
Christopher
The price is ¥23,931
¥27,161 total
includes taxes & fees
May 20 - May 21
Margaritaville Jacksonville Beach

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,010 reviews)
"Great location, the beach and restaurants are right there! Clean rooms, good breakfast, tea and coffee in the lobby around the clock. Beach towels provided. Highly recommend!"
United States
Tatyana
The price is ¥22,008
¥24,979 total
includes taxes & fees
May 20 - May 21
Best Western Oceanfront

Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront
3.0 star property
5.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,004 reviews)
"Perfect location to the beach and clean room"
United States
Caulan
The price is ¥34,390
¥39,033 total
includes taxes & fees
Jun 4 - Jun 5
Four Points by Sheraton Jacksonville Beachfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
5.8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (685 reviews)
"We stay here once a year and always enjoy it. Staff is great and so is the breakfast"
United States
Selina
The price is ¥31,756
¥36,043 total
includes taxes & fees
May 13 - May 14
Springhill Suites By Marriott Jacksonville Beach Oceanfront

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.5 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,004 reviews)
"We were extremely pleased with our room and the breakfast. The staff was fantastic & very helpful at every turn :) "
United States
Tonya
The price is ¥23,729
¥26,458 total
includes taxes & fees
May 25 - May 26
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
Southside, 7.7 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1,003 reviews)
"Room clean, excellent location near shooping and Restaurants. Good breakfast. 14 minutes to Mayo Clinic."
United States
Damaris
The price is ¥19,384
¥22,001 total
includes taxes & fees
May 17 - May 18
Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Hampton Inn Jacksonville Beach/Oceanfront

Hampton Inn Jacksonville Beach/Oceanfront
3.0 star property
6.3 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (2,684 reviews)
"The place was so nice and the staff was amazing ! Beautiful place to stay !!!! "
United States
Melissa
The price is ¥25,643
¥29,105 total
includes taxes & fees
May 20 - May 21
Hampton Inn Jacksonville Beach/Oceanfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to Mayo Clinic Florida

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet friendly
WiFi included
Lobby lounge
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
9.4
Exceptional
501 reviews
View
Breakfast, lunch, dinner served; American cuisine
Hilton Jacksonville At Mayo Clinic
4.5 star property
9.4
Exceptional
220 reviews
View
Lobby
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
9.0
Wonderful
1,006 reviews
View
Lobby sitting area
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
8.8
Excellent
1,005 reviews
View
Terrace/patio
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
8.4
Very Good
772 reviews
View

Top Mayo Clinic Florida Hotel Reviews

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, check out the 49 hotels and other accommodations you'll find within a mile.
What's the best place to stay close to Mayo Clinic Florida?
Adjacent to Mayo Clinic Florida, Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and an outdoor pool. Other good choices close by include Hilton Jacksonville At Mayo Clinic and Residence Inn By Marriott Jacksonville - Mayo Clinic Area.
How many hotels will I find near Mayo Clinic Florida?
Expedia has 49 hotels and other accommodations within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals available near Mayo Clinic Florida.
Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic Florida?
To access more information about picking new dates or cancelling your stay near Mayo Clinic Florida, head over to our customer service page.
What can I see and do near Mayo Clinic Florida?
You can catch a show at SeaWalk Pavillion, Players by the Sea, and SeaWalk Pavillion. Spend some time exploring the natural beauty of Huguenot Park, Oceanfront Park, and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.

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