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Compare 5,526 hotels close to Main Street with room rates, reviews, and availability. Most hotels are fully refundable.

Hyannis Travel Inn

2.5 star property
9.6 out of 10, Exceptional, (1022)
"Stayed there many times! Great place"
The price is ¥14,986
¥17,153 total
includes taxes & fees
Oct 15 - Oct 16
Hyannis Travel Inn

Craigville Beach Inn

2.0 star property
8.6 out of 10, Excellent, (445)
"Love the craigville inn. We have stayed here multiple times and will continue to do so!"
The price is ¥19,504
¥22,322 total
includes taxes & fees
Oct 12 - Oct 13
Craigville Beach Inn

The Ocean View

2.5 star property
9.0 out of 10, Wonderful, (130)
"Was a great, convenient property close to the beach."
The price is ¥27,645
¥31,639 total
includes taxes & fees
Oct 16 - Oct 17
The Ocean View

Fairfield Inn & Suites by Marriott Cape Cod Hyannis

2.5 star property
8.8 out of 10, Excellent, (618)
"Clean Room and very accessible to everything "
The price is ¥15,270
¥17,476 total
includes taxes & fees
Nov 2 - Nov 3
Fairfield Inn & Suites by Marriott Cape Cod Hyannis

SeaCoast Inn

2.0 star property
9.0 out of 10, Wonderful, (739)
"Nice location to Main St and the harbor"
The price is ¥15,986
¥18,296 total
includes taxes & fees
Oct 13 - Oct 14
SeaCoast Inn

Sea Street Inn

4.0 star property
9.8 out of 10, Exceptional, (45)
"Very nicely renovated small property with a fantastic breakfast."
The price is ¥37,382
¥42,784 total
includes taxes & fees
Nov 6 - Nov 7
Sea Street Inn

Anchor In Distinctive Waterfront Lodging

3.0 star property
9.4 out of 10, Exceptional, (1004)
"Beautiful quaint hotel, with a nice view of the water. The place has a pool, a fire pit and nice spacious rooms. Would stay again. "
Anchor In Distinctive Waterfront Lodging

Holiday Inn Hyannis by IHG

3.0 star property
8.2 out of 10, Very Good, (951)
"Great place to stay "
The price is ¥14,817
¥16,958 total
includes taxes & fees
Nov 2 - Nov 3
Holiday Inn Hyannis by IHG

Courtyard By Marriott Cape Cod Hyannis

3.0 star property
8.8 out of 10, Excellent, (478)
"Pretty nice location"
The price is ¥17,804
¥20,377 total
includes taxes & fees
Nov 3 - Nov 4
Courtyard By Marriott Cape Cod Hyannis

Uncommoner Hotel by Reverie Boutique Collection

3.0 star property
9.2 out of 10, Wonderful, (64)
"Such a nice place to stay for a weekend getaway, we will definitely be back!"
The price is ¥18,256
¥20,893 total
includes taxes & fees
Oct 14 - Oct 15
Uncommoner Hotel by Reverie Boutique Collection

Hampton Inn & Suites Cape Cod-West Yarmouth

2.5 star property
8.8 out of 10, Excellent, (1003)
"LOVELY property with excellent staff!"
The price is ¥17,233
¥19,723 total
includes taxes & fees
Nov 2 - Nov 3
Hampton Inn & Suites Cape Cod-West Yarmouth

Cape Sands Inn

2.5 star property
8.2 out of 10, Very Good, (1017)
"This was a very clean place to stay we felt safe and it was convenient and not far from places."
The price is ¥10,370
¥11,870 total
includes taxes & fees
Oct 13 - Oct 14
Cape Sands Inn

Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area

2.0 star property
6.8 out of 10, (1002)
"pool was great and so was the staff"
The price is ¥10,432
¥11,939 total
includes taxes & fees
Oct 13 - Oct 14
Days Inn by Wyndham West Yarmouth/Hyannis Cape Cod Area

Bayside Resort Hotel

3.0 star property
8.8 out of 10, Excellent, (1506)
"Centrally located... clean and modern. Would definitely stay there again and would definitely recommend,"
Bayside Resort Hotel

Best Western Cape Cod Hotel

2.5 star property
7.2 out of 10, Good, (1010)
"Great stay"
The price is ¥14,833
¥16,977 total
includes taxes & fees
Oct 15 - Oct 16
Best Western Cape Cod Hotel

Comfort Inn Hyannis - Cape Cod

2.5 star property
8.0 out of 10, Very Good, (1001)
"Clean, comfortable, affordable in a convenient location. "
The price is ¥14,832
¥16,976 total
includes taxes & fees
Nov 2 - Nov 3
Comfort Inn Hyannis - Cape Cod

Margaritaville Resort Cape Cod

4.0 star property
8.6 out of 10, Excellent, (378)
"Very nice place to stay "
Margaritaville Resort Cape Cod

Hyannis Harbor Hotel

3.5 star property
8.0 out of 10, Very Good, (1006)
""It was priced very reasonable and in a great location""
The price is ¥17,946
¥26,645 total
includes taxes & fees
Oct 19 - Oct 20
Hyannis Harbor Hotel

Doubletree by Hilton Cape Cod - Hyannis

4.0 star property
8.4 out of 10, Very Good, (864)
"Great location, awesome area for amenities, delicious cookies, as usual!"
The price is ¥17,804
¥20,377 total
includes taxes & fees
Nov 2 - Nov 3
Doubletree by Hilton Cape Cod - Hyannis

Relax Inn Cape Cod

2.0 star property
6.4 out of 10, (743)
"Good staff, good room, good price."
The price is ¥10,266
¥11,751 total
includes taxes & fees
Oct 13 - Oct 14
Relax Inn Cape Cod
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Main Street Hotel Reviews

Hotels near other Main Street attractions

Frequently asked questions

What's the area like around Main Street?
If you're planning to come to the area to visit Main Street, take some time to see the rest of the sights while you're in town. If you're looking for a convenient place to stay, check out the 22 hotels and other accommodations you'll find within a mile.
What's the best place to stay near Main Street?
Long Dell Inn is one of the top choices for your stay based on our traveler data, and this B&B offers free breakfast and free parking. It's located 2.5 mi (4.1 km) from Main Street. Other good options within a few miles include Craigville Beach Inn and The Ocean View.
How many hotels will I find near Main Street?
Expedia has 22 hotels and other accommodations within a mile from Main Street.
If I need to cancel the hotel reservation for my stay near Main Street, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Add dates, click "Search", then you can filter by "fully refundable" to view the top deals on offer near Main Street.
Where can I learn more about changing or cancelling my trip in the area near Main Street?
To access more information about picking new dates or cancelling your stay near Main Street, head over to our customer service page.
What can I see and do near Main Street?
Study the collections at Centerville Historical Museum, Cahoon Museum of American Art, or Toad Hall Classic Sports Car Museum. You can check out the local talent at Cape Cod Melody Tent, Cotuit Center for the Arts, and Barnstable Performing Arts Center. Dip your toes in the water at Craigville Beach, Keyes Beach, and Dowses Beach.