Lupus Vacation Rentals

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Check prices for these dates

Tonight
Dec 23 - Dec 24
Tomorrow
Dec 24 - Dec 25
This weekend
Dec 26 - Dec 28
Next weekend
Jan 2 - Jan 4

Our top choices for Lupus vacation rentals

Exterior
Step Back in Time Near The Missouri River

Cottage in Jamestown

Step Back in Time Near The Missouri River
9.8 out of 10, Exceptional, (17)
"It was very beautiful well stocked, and the owner was very mindful and considerate as to what people needed to be well accommodated and comfortable. I like that."
United States
Latonya M.
The price is ￥23,692
￥36,087 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Step Back in Time Near The Missouri River
Fridge, microwave, oven, stovetop
Como's Finest- A Home Away From Home- Sleeps 10

Apartment in Columbia

Como's Finest- A Home Away From Home- Sleeps 10
8.8 out of 10, Excellent, (5)
"Overall out stay was very nice. Pictures make the place look larger but it was nice and we had enough space. There was an issue with the upstairs toilet not flushing but they came to check it out immediately. Very nice people to work with"
United States
Melissa M.
The price is ￥12,709
￥41,710 total
includes taxes & fees
Dec 25 - Dec 26
Como's Finest- A Home Away From Home- Sleeps 10
Fridge, microwave, oven, stovetop
~A Home Away From Home~Sleeps 8~

Apartment in Columbia

~A Home Away From Home~Sleeps 8~
2.0 star property
9.2 out of 10, Wonderful, (5)
"We're going to book again this time next year."
United States
Donna T.
The price is ￥11,924
￥40,251 total
includes taxes & fees
Jan 19 - Jan 20, 2026
~A Home Away From Home~Sleeps 8~
Outdoor dining
Near University of Missouri | Fitness Center

Condo in Columbia

Near University of Missouri | Fitness Center
2.0 star property
10.0 out of 10, Exceptional, (1)
The price is ￥17,615
￥23,143 total
includes taxes & fees
Dec 25 - Dec 26
Near University of Missouri | Fitness Center
Fridge, microwave, oven, stovetop
It's a Gem ! Comfy Hideaway for R & R ~ King Bed !

Vacation Home in Columbia

It's a Gem ! Comfy Hideaway for R & R ~ King Bed !
9.8 out of 10, Exceptional, (20)
"Everything was great from check in to check out. "
United States
Jason L.
The price is ￥22,907
￥52,663 total
includes taxes & fees
Jan 14 - Jan 15, 2026
It's a Gem ! Comfy Hideaway for R & R ~ King Bed !
Smart TV
3BR/1.5BA Cozy, Affordable Retreat in Columbia, 10-min from Mizzou

Vacation Home in Columbia

3BR/1.5BA Cozy, Affordable Retreat in Columbia, 10-min from Mizzou
10.0 out of 10, Exceptional, (27)
"Clean property, quiet area, amenities appeared to be brand new. Host was very responsive and we enjoyed our stay. "
United States
Kevin R.
The price is ￥13,180
￥39,018 total
includes taxes & fees
Jan 5 - Jan 6, 2026
3BR/1.5BA Cozy, Affordable Retreat in Columbia, 10-min from Mizzou
Fridge, microwave, oven, stovetop
Comfy Home~Teal Feel~ Sleeps 8

Apartment in Columbia

Comfy Home~Teal Feel~ Sleeps 8
The price is ￥11,924
￥36,328 total
includes taxes & fees
Dec 25 - Dec 26
Comfy Home~Teal Feel~ Sleeps 8
Fridge, microwave, oven, stovetop
3 Bedroom 1 Bath Pet Friendly 5 min to MU

Vacation Home in Columbia

3 Bedroom 1 Bath Pet Friendly 5 min to MU
10.0 out of 10, Exceptional, (9)
"Very clean and cute home! Great location, close to coffee shops and restaurants. We enjoyed our stay!"
United States
Lori S.
The price is ￥11,768
￥35,460 total
includes taxes & fees
Dec 29 - Dec 30
3 Bedroom 1 Bath Pet Friendly 5 min to MU
Fridge, microwave, oven, stovetop
2 Bed 1 Bath Southside Columbia 7 min to Mizzou

Apartment in Columbia

2 Bed 1 Bath Southside Columbia 7 min to Mizzou
10.0 out of 10, Exceptional, (10)
"Nice and clean apartment. Comfortable beds. Great place to stay."
United States
Paul S.
The price is ￥9,414
￥33,106 total
includes taxes & fees
Jan 6 - Jan 7, 2026
2 Bed 1 Bath Southside Columbia 7 min to Mizzou
Outdoor dining
Unique traincar stay at the Katy Caboose!

Cottage in Hartsburg

Unique traincar stay at the Katy Caboose!
9.4 out of 10, Exceptional, (10)
"We loved the 3 taverns in town. Great vibe in a tiny town. "
United States
Dusty
The price is ￥15,361
￥27,681 total
includes taxes & fees
Dec 25 - Dec 26
Unique traincar stay at the Katy Caboose!
Pool
Super Close to Mizzou Condo 2 Bed 1 Bath

Apartment in Columbia

Super Close to Mizzou Condo 2 Bed 1 Bath
10.0 out of 10, Exceptional, (8)
"The property was in a very convenient location and the property owner was ver responsive.I would stay again!!"
United States
Carmen H.
The price is ￥10,983
￥34,204 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Super Close to Mizzou Condo 2 Bed 1 Bath
2 bedrooms, desk, free WiFi, bed sheets
Historic Cozy Apartment 1 Bedroom In Peaceful Boonville

Apartment in Boonville

Historic Cozy Apartment 1 Bedroom In Peaceful Boonville
2.0 star property
9.2 out of 10, Wonderful, (14)
"Apartment very clean & neat. Convenient location. "
United States
judith s.
The price is ￥13,980
￥31,942 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Historic Cozy Apartment 1 Bedroom In Peaceful Boonville
Private kitchen
Whispering Woods Hideaway ~ Large Home ~ 85 in TV

Vacation Home in Columbia

Whispering Woods Hideaway ~ Large Home ~ 85 in TV
2.0 star property
10.0 out of 10, Exceptional, (1)
"Clean house. Very responsive"
United States
Gary B.
The price is ￥22,907
￥70,605 total
includes taxes & fees
Jan 1 - Jan 2, 2026
Whispering Woods Hideaway ~ Large Home ~ 85 in TV
Fridge, microwave, oven, stovetop
Zou Lodge - Modern 3BR With King Beds Near Mizzou

Vacation Home in Columbia

Zou Lodge - Modern 3BR With King Beds Near Mizzou
10.0 out of 10, Exceptional, (13)
"Location was great - house was spacious and with thoughtful amenities. Quiet, safe neighborhood that's easy to access. Will definitely stay here again!"
United States
natalie l.
The price is ￥25,104
￥45,809 total
includes taxes & fees
Dec 28 - Dec 29
Zou Lodge - Modern 3BR With King Beds Near Mizzou
Fridge, microwave, oven, stovetop
3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena

Vacation Home in Columbia

3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena
8.8 out of 10, Excellent, (5)
"We had a great weekend in Columbia the property was close to everything we needed. Would definitely recommend and stay again "
United States
Jason C.
The price is ￥17,651
￥46,481 total
includes taxes & fees
Dec 30 - Dec 31
3-bedroom Ranch Duplex in charming Columbia with WiFi, 6 miles to Mizzou Arena
Exterior
Cozy cabin getaway with hot-tub under stars!

Cabin in Ashland

Cozy cabin getaway with hot-tub under stars!
9.6 out of 10, Exceptional, (22)
"This cabin was great and the setting was amazing. So peaceful! I would definitely stay here again."
United States
Tom M.
The price is ￥21,182
￥37,186 total
includes taxes & fees
Dec 28 - Dec 29
Cozy cabin getaway with hot-tub under stars!
Smart TV
Brand New Modern Downtown Condo designed by award-winning architect!

Condo in Columbia

Brand New Modern Downtown Condo designed by award-winning architect!
10.0 out of 10, Exceptional, (83)
"It was clean and very nice- close to Mizzou campus so very convenient for our stay- will stay again!"
United States
Kristin G.
The price is ￥32,008
￥53,817 total
includes taxes & fees
Jan 8 - Jan 9, 2026
Brand New Modern Downtown Condo designed by award-winning architect!
Fridge, microwave, oven, coffee/tea maker
Downtown Luxury Suite

Apartment in Columbia

Downtown Luxury Suite
9.6 out of 10, Exceptional, (73)
"Great unit and location. We enjoyed the stay. "
United States
Andrew
The price is ￥28,242
￥33,790 total
includes taxes & fees
Dec 25 - Dec 26
Downtown Luxury Suite
Fridge, microwave, oven, stovetop
Katy Trail Pull Off

Vacation Home in Boonville

Katy Trail Pull Off
9.6 out of 10, Exceptional, (99)
"Great home, quiet neighborhood, and comfy beds. Perfect home for our stay and we will stay again. "
United States
Samantha H.
The price is ￥14,827
￥27,873 total
includes taxes & fees
Jan 5 - Jan 6, 2026
Katy Trail Pull Off
Fridge, microwave, oven, stovetop
Newly Built Home w/ Fresh Design!

Vacation Home in Columbia

Newly Built Home w/ Fresh Design!
9.8 out of 10, Exceptional, (22)
"Beautiful home! Easy to get to from downtown Columbia. Not far from highway 70. "
United States
Kathy S.
The price is ￥34,832
￥56,798 total
includes taxes & fees
Jan 13 - Jan 14, 2026
Newly Built Home w/ Fresh Design!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Lupus Hotel Reviews

Drury Plaza Hotel Columbia East

Drury Plaza Hotel Columbia East

10/10 Excellent
"Spotless room, friendly staff, wonderful food for a family with younger children. "
Melanie E 2-night trip
Posted 1 day ago
Drury Plaza Hotel Columbia East

Find out more about Lupus

Search for holiday rentals in Lupus on Expedia! You can easily find your home rentals, villas, holiday apartments in Lupus using one of the methods below:

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Look no further and take a look at our great range of rental properties in Lupus!

Frequently asked questions

Can I find a vacation rental in Lupus?

Yes, there are vacation rentals near the most popular points of interest in Lupus, or you can choose a secluded option if you'd like a relaxing place to stay.

What are some of the best vacation home rentals that Lupus has to offer?

3BR/1.5BA Cozy, Affordable Retreat in Columbia, 10-min from Mizzou: This vacation home rental near Lupus offers a patio, a garden, and air-conditioning to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms in addition to a kitchen with a fridge and a microwave.

What can I see and do in Lupus?

Explore the area and family-friendly sights such as Midway Golf and Games, or get out into nature at a spot like Shelter Gardens. In the larger area, you’ll find Rock Bridge Memorial State Park and Mizzou Arena.

What are vacation rentals like in Lupus?

Vacation rentals are privately owned accommodations you can reserve for a few days or a quick weekend in Lupus. Vacation rentals feature amenities such as WiFi and washers and dryers so you'll feel just like you're staying in your own home. If you're concerned about a clean environment, vacation rentals can provide a sense of privacy away from public hotel elevators and busy front desks while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive option for a family trip or a small group gathering.