Louisiana, MO

Travel Guide

A river with a large, rusted metal bridge and a smaller bridge in the background.
A waterfront town with a prominent American flag, houses, and autumn-colored trees.
A waterfront town with a hill in the background, a flag on a pole, and buildings along the shore.
A river with a dam, surrounded by greenery and a clear sky.
A tree-lined landscape with a river and fields.
River's Edge Motel

River's Edge Motel

2 out of 5
201 Mansion St Louisiana MO
The price is ¥12,939 per night from Jun 28 to Jun 29
¥12,939
¥14,691 total
Jun 28 - Jun 29
includes taxes & fees
Stay at this motel in Louisiana. Enjoy free WiFi, free parking, and a 24-hour front desk. Our guests praise the helpful staff in our reviews.
9/10 Wonderful! (369 reviews)
"The bed was very comfortable.The room was nice and cold like I like. The managers were amazing. I forgot to tell them no maid service. When we got back to the room, it had fresh towels. I'm not very trusting of hotel personnel because of past theft. So normally I do not want maid service. However, ..."

Reviewed on Jun 21, 2026

River's Edge Motel
The Eagles Nest Inn

The Eagles Nest Inn

3 out of 5
215 Georgia St Louisiana MO
The price is ¥17,185 per night from Jul 23 to Jul 24
¥17,185
¥19,511 total
Jul 23 - Jul 24
includes taxes & fees
Stay at this inn in Louisiana. Enjoy free WiFi, free parking, and housekeeping.
9.4/10 Exceptional! (25 reviews)
"vg"

Reviewed on May 31, 2026

The Eagles Nest Inn
The Yellow Rose Historic Home

The Yellow Rose Historic Home

Louisiana MO
The price is ¥40,041 per night from Jul 5 to Jul 6
¥40,041
¥57,897 total
Jul 5 - Jul 6
includes taxes & fees
Book a stay at this family-friendly vacation home in Louisiana. Enjoy free WiFi, laundry facilities, and an in-room coffeemaker.
9.8/10 Exceptional! (18 reviews)
"Our second time here and there will be many more times I’m sure. Love this house! As you walk in there is a grand staircase , you turn and there is a living room with furniture befitting the era of the house. The grand piano is another great touch. The woodwork is amazing. That’s just the beginning ..."

Reviewed on Jun 8, 2026

The Yellow Rose Historic Home
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
The Yellow Rose Historic Home

The Yellow Rose Historic Home

Louisiana MO
Book a stay at this family-friendly vacation home in Louisiana. Enjoy free WiFi, laundry facilities, and an in-room coffeemaker.
9.8/10 Exceptional! (18 reviews)
"Our second time here and there will be many more times I’m sure. Love this house! As you walk in there is a grand staircase , you turn and there is a living room with furniture befitting the era of the house. The grand piano is another great touch. The woodwork is amazing. That’s just the beginning ..."

Reviewed on Jun 8, 2026

The Yellow Rose Historic Home
Lighthouse Inn & Suites

Lighthouse Inn & Suites

4 out of 5
612 Mark Twain Ave Hannibal MO
Stay at this aparthotel in Hannibal. Enjoy free WiFi, free parking, and dry cleaning or laundry services. Popular attractions Molly Brown Museum and Home and ...
9/10 Wonderful! (31 reviews)
"Wonderful place to stay!"

Reviewed on Jun 25, 2026

Lighthouse Inn & Suites
Gorgeous Victorian with Seasonal Pool , sleeps 8, pet friendly close to downtown

Gorgeous Victorian with Seasonal Pool , sleeps 8, pet friendly close to downtown

Hannibal MO
Stay at this vacation home in Hannibal. Enjoy free WiFi, private pools, and a garden. Popular attractions Rockcliffe Mansion and Molly Brown Museum and Home ...
9.4/10 Exceptional! (13 reviews)
"Family friendly and clean rooms. The checkout process was very short and easy. It was very easy to reach the hostess and she responded very quickly to all inquiries. The house itself is nice and as stated historic. Overall, it was a great experience!"

Reviewed on Jun 22, 2026

Gorgeous Victorian with Seasonal Pool , sleeps 8, pet friendly close to downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.