The Best Hotels Closest to Lewis and Clark Interpretive Center in St. Louis for 2026

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Our top choices for Lewis and Clark Interpretive Center hotels

A modern lobby with patterned armchairs, a fireplace, and a large TV on the wall.

A hotel dining area with tables and chairs, a kitchen in the background, and large windows with curtains.

A lobby with a sofa, armchairs, a chandelier, decorative mirrors, and a fireplace.

A modern lobby with a blue patterned carpet, a white sofa, patterned armchairs, and a decorative mirror.

1. Holiday Inn Express & Suites Edwardsville by IHG

10.9 km from Lewis and Clark Interpretive Center

Judy

￥20,470

￥23,536 total

includes taxes & fees

Sep 20 - Sep 21

A modern living room with a stone fireplace, a reception desk, and a large window.

A modern living room with a stone fireplace, green and beige sofas, a round coffee table, and large windows offering a view of trees.

A Fairfield by Marriott hotel with a modern design, featuring a covered entrance and multiple floors.

An indoor swimming pool with clear blue water, surrounded by lounge chairs and tables, large windows with a view of trees, and a tiled floor.

2. Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

6.2 km from Lewis and Clark Interpretive Center

Sabra

￥17,439

￥19,354 total

includes taxes & fees

Sep 20 - Sep 21

A hotel lobby with blue seating, a flat-screen TV, and a fireplace.

A spacious dining area with high tables and booths, large windows, and a view of greenery outside.

A reception area with two dark wooden reception desks, a stone-textured wall, and a sign reading "Comfort INN".

A hotel room with a large bed, two bedside tables, a desk, and a chair.

3. Comfort Inn Edwardsville - St. Louis

9.4 km from Lewis and Clark Interpretive Center

Ashley

￥15,538

￥17,866 total

includes taxes & fees

Sep 27 - Sep 28

A multi-story hotel with balconies, a parking lot with marked spaces, and a clear sky.

A reception desk with a 'NO Pets Allowed' sign, a 'Please ring door bell' sign, and a window with a view of a parking lot.

A red door with a prohibition sign against tobacco, e-cigarettes, and cannabis.

A hotel room with two beds, each with a wooden headboard, white bedding, and a patterned bedspread.

4. Bel Air Motel

6.3 km from Lewis and Clark Interpretive Center

Tai

￥9,962

￥12,462 total

includes taxes & fees

Sep 6 - Sep 7

An outdoor patio with a circular fire pit, seating, and a grill area.

A modern hotel room with a sectional sofa, a small table, a lamp, and a large window with sheer curtains.

A multi-story hotel with a covered entrance and a sign reading "Towneplace Suites by Marriott".

An indoor swimming pool with clear water, a 15-meter length marker, and a 5-foot depth marker. There are lounge chairs and a table with chairs around the pool.

5. TownePlace Suites by Marriott St. Louis Edwardsville, IL

10.9 km from Lewis and Clark Interpretive Center

Chris

￥25,913

￥29,795 total

includes taxes & fees

Oct 4 - Oct 5

A spacious lobby with a high ceiling, large windows, and a variety of seating options including sofas and chairs.

A spacious indoor area with a large table and chairs, a sofa, and a staircase leading to an upper level.

A restaurant with a brick wall, large windows, and a seating area with tables and chairs.

An indoor swimming pool with clear glass walls, a tiled edge, and a ceiling with metal beams. There are lounge chairs and tables around the pool area.

6. Drury Inn & Suites St. Louis Collinsville

15.4 km from Lewis and Clark Interpretive Center

James

￥17,343

￥19,941 total

includes taxes & fees

Sep 14 - Sep 15

A brick building with a wooden gazebo in front.

A statue of a Native American figure with a horse, a Route 66 sign, a map, and a clock on the wall.

A hotel room with two beds, a dresser, a television, and a bathroom visible through an open door.

A compact kitchen with a sink, microwave, and stove, a wooden cabinet, and a television mounted on the wall.

7. Country Hearth Inn & Suites Edwardsville St. Louis

10.8 km from Lewis and Clark Interpretive Center

les

￥20,137

￥23,153 total

includes taxes & fees

Sep 6 - Sep 7

A spacious dining area with high ceilings, multiple dining tables, and chairs.

A hotel reception area with a wooden reception desk, a framed picture of a building, and a blue wall with framed items.

A Hampton Inn & Suites with a clear entrance, a parking lot, and a flagpole.

A hotel room with a sofa, two chairs, a table, and a flat-screen TV mounted on the wall.

8. Hampton Inn & Suites St. Louis-Edwardsville

10.1 km from Lewis and Clark Interpretive Center

Tashae

￥17,562

￥19,666 total

includes taxes & fees

Oct 5 - Oct 6

A cozy lounge area with leather seating, a wooden coffee table, and a fireplace.

A hotel bathroom with a large bathtub, a sofa, a microwave, and a desk with a lamp.

An indoor swimming pool with lounge chairs and tables, large windows, and a ceiling with exposed beams.

A hotel room with a bed, a sofa, a desk, and a chair.

9. Best Western Plus Pontoon Beach

6.8 km from Lewis and Clark Interpretive Center

Shellie

￥16,155

￥17,929 total

includes taxes & fees

Oct 4 - Oct 5

A modern dining area with a long table, colorful chairs, and decorative hanging lights.

A hotel room with two beds, a flat-screen TV, a microwave, and a desk with a chair.

A Hampton Inn & Suites hotel with a modern design, featuring a large entrance and a well-lit facade.

A modern hotel room with a white sink, a framed picture of a colorful building, a microwave, and a seating area with a patterned rug.

10. Hampton Inn & Suites St. Louis/Alton

14 km from Lewis and Clark Interpretive Center

Kristen

￥20,373

￥23,222 total

includes taxes & fees

Sep 20 - Sep 21

A hotel room with two beds, a desk, a chair, and a wall-mounted lamp.

A Holiday Inn Express building with a stone facade, a covered entrance, and a parking lot.

An indoor swimming pool with a lifeguard on duty sign, a pool lift, and chairs around the pool area.

A breakfast station with self-service options, a sign indicating hot food availability, and a digital menu board displaying breakfast items.

11. Holiday Inn Express Troy by IHG

18 km from Lewis and Clark Interpretive Center

Donald

￥18,439

￥20,463 total

includes taxes & fees

Sep 20 - Sep 21

A modern bathroom with a red bathtub, a white sink, and a shower. There is a bed with a white mattress and a grey curtain in the adjacent room.

A modern kitchen area with a dining table and chairs, a refrigerator, a coffee machine, and a vending machine.

A modern room with a stone wall, a flat-screen TV, two red chairs, a small table, and a view of the outside.

A spacious interior with a high ceiling, a staircase with wooden balusters, and a modern kitchen area in the background.

12. Red Lion Inn & Suites Pontoon Beach

5.6 km from Lewis and Clark Interpretive Center

Jennifer

￥11,239

￥12,724 total

includes taxes & fees

Oct 4 - Oct 5

An indoor swimming pool with a lifeguard chair, a lifebuoy, and a mural of a beach scene.

A breakfast area with a wooden counter, a microwave, and a coffee machine.

A hotel room with a bed, a desk, a chair, a lamp, a mirror, and a television.

A hotel room with two beds, a desk with a TV, a chair, and a window with a view of the outside.

13. Super 8 by Wyndham Troy IL/St. Louis Area

17.8 km from Lewis and Clark Interpretive Center

Donta

￥10,626

￥11,793 total

includes taxes & fees

Sep 13 - Sep 14

A buffet area with a wooden counter, various food items, and a coffee station.

A hotel room with a sofa, a small table, a lamp, and a TV.

A Comfort Inn hotel with a simple facade, a parking lot, and a clear sky in the background.

A reception area with a wooden reception desk, a stone wall with a clock, and framed pictures on the wall.

14. Comfort Inn Collinsville near St. Louis

15.3 km from Lewis and Clark Interpretive Center

Jose Rene

￥16,120

￥18,534 total

includes taxes & fees

Sep 27 - Sep 28

A hotel room with two beds, a desk, a mirror, and a television.

A swimming pool with a clear blue water, surrounded by lounge chairs and a sunbed.

A laundry room with two washing machines, a drying rack, and instructional posters on the wall.

A hotel with a central entrance, multiple windows, and a parking lot.

15. Red Roof Inn St Louis - Troy, IL

18 km from Lewis and Clark Interpretive Center

crystal

￥10,126

￥11,239 total

includes taxes & fees

Sep 13 - Sep 14

An outdoor patio area with multiple tables and chairs, surrounded by neatly trimmed bushes and a gravel path.

A modern building with a blue and white color scheme, labeled "The Great Rivers." It features a parking lot with several cars and a gas station in the foreground.

A gym with treadmills, exercise equipment, and a water dispenser.

A hotel named 'The Great Rivers' with a modern architectural design, featuring a prominent sign and a parking lot in front.

16. The Great Rivers, an Ascend Collection Hotel

11.5 km from Lewis and Clark Interpretive Center

Elizabeth

￥13,624

￥15,529 total

includes taxes & fees

Sep 27 - Sep 28

A modern kitchen with marble countertops, a built-in coffee station, and a seating area with metal chairs and tables.

A motel with multiple floors, a parking lot, and a clear sky.

A hotel room with a large bed, a nightstand with a phone, and wall-mounted lights.

17. Days Inn by Wyndham Troy IL

18 km from Lewis and Clark Interpretive Center

Marek

￥11,551

￥12,820 total

includes taxes & fees

Sep 7 - Sep 8

A lobby with a blue sofa, patterned cushions, a reception desk, and a mural of a moon and arch.

A hotel with a central entrance, multiple floors, and a clear sky.

A swimming pool with clear blue water, surrounded by lounge chairs and a tiled wall.

A breakfast bar with a microwave, coffee makers, and a fruit display.

18. La Quinta Inn & Suites by Wyndham Pontoon Beach

6.9 km from Lewis and Clark Interpretive Center

Weldon

￥18,576

￥21,359 total

includes taxes & fees

Oct 4 - Oct 5

A hotel entrance with a covered driveway and a parking area.

A hotel room with two beds, a TV, a desk, and a chair.

A hotel room with two desks, each with a computer, a lamp, and a chair.

A dining area with multiple tables and chairs, a kitchen in the background, and artwork on the walls.

19. Best Western Plus Parkway Hotel

13.9 km from Lewis and Clark Interpretive Center

Steve

￥12,551

￥14,306 total

includes taxes & fees

Sep 14 - Sep 15

A lobby with a central table, seating area, and a stone pillar with a mirror.

A modern hotel lobby with a sectional sofa, armchairs, a coffee table, and abstract wall art.

A restaurant with multiple tables, chairs, and a stone fireplace.

An outdoor patio with wicker furniture, a stone fire pit, and potted plants.

20. DoubleTree by Hilton Collinsville - St. Louis

15.6 km from Lewis and Clark Interpretive Center

Jenni

￥21,995

￥25,291 total

includes taxes & fees

Sep 27 - Sep 28

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Compare popular hotels close to Lewis and Clark Interpretive Center

Property	Star rating	Guest rating
Holiday Inn Express & Suites Edwardsville by IHG	9.2 Wonderful 905 reviews	View
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City	9.2 Wonderful 528 reviews	View
Comfort Inn Edwardsville - St. Louis	8.4 Very Good 927 reviews	View
Bel Air Motel	8.6 Excellent 236 reviews	View
TownePlace Suites by Marriott St. Louis Edwardsville, IL	9.0 Wonderful 210 reviews	View

Top Lewis and Clark Interpretive Center Hotel Reviews

21C Museum Hotel St Louis

10/10 Excellent

"Excellent hotel , friendly , loved all public area including the pool"

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent

"It was an excellent stay. Room clean, everything great. The breakfast top level."

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

8/10 Good

"We were there for the Cardinals game and they were great with check-in and leaving the car in parking. Had a problem with noisy neighbors waking us in the middle of the night. We called the front desk but it was not resolved."

Hyatt Regency St. Louis at The Arch

10/10 Excellent

"Location was great. Hotel staff was nice and helpful."

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

10/10 Excellent

"."

Home2 Suites by Hilton St. Louis Downtown

10/10 Excellent

"Valet parking expensive. Good breakfast. I didn’t walk the area when it got dark."

Live by Loews - St.Louis

10/10 Excellent

"This is an amazingly clean and comfortable hotel. It is directly across from the baseball field and there is a parking garage connected to the building for $40. It is a 10min walk to the Gateway Arch and plenty of restaurants to choose from. Right downtown and if there is no game going on it is extremely quiet. Not the loud hussle and bussle of most downtown areas."

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

10/10 Excellent

"Great place"

Super 8 by Wyndham St. Louis North

10/10 Excellent

"Nice staff and clean rooms"

Other attractions near Lewis and Clark Interpretive Center

Lewis and Clark Confluence Tower

Bring a camera when you climb this tower, which offers fantastic views across the Mississippi River and provides insight into a fascinating piece of history.

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Lewis and Clark State Memorial Park

Explore the great outdoors at Lewis and Clark State Memorial Park, a lovely green space in Hartford. Discover the area's museums and monuments.

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Hartford Park

After visiting Hartford Park, make a plan to see the other sights and activities in Hartford. Discover the area's museums and monuments.

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Hartford City Hall

Hartford City Hall is just one of the places to see in Hartford, so why not enjoy the other things to explore during your travels? Amble around the area's riverfront or experience its museums.

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Jones-Confluence Point State Park

You can take time to visit Jones-Confluence Point State Park during your travels to West Alton. You can attend a sporting event while in the area.

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Dads Club Park

Explore the great outdoors at Dads Club Park, a lovely green space in South Roxana.

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South Roxana Dad's Club Park

South Roxana Dad's Club Park is just one of the places to see in South Roxana, so why not enjoy the other things to explore during your travels?

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Frequently asked questions

What's the area like around Lewis and Clark Interpretive Center?

Lewis and Clark Interpretive Center is located in a welcoming area of Hartford that travelers like for its sporting events. You'll find 14 hotels and other accommodations within a few miles for a convenient home base.

Where is the best place to stay close to Lewis and Clark Interpretive Center?

Hyatt Regency St. Louis at The Arch is one of the top choices for your stay based on our traveler data, and this hotel offers 3 restaurants and 2 bars. You'll find it 13 mi (20.9 km) from Lewis and Clark Interpretive Center. Other good options around the area include Super 8 by Wyndham St. Louis North and Drury Plaza Hotel St. Louis at the Arch.

How many hotels are there near Lewis and Clark Interpretive Center?

Expedia has 14 hotels and other accommodations a few miles from Lewis and Clark Interpretive Center.

If I need to cancel the hotel reservation for my stay near Lewis and Clark Interpretive Center, will I receive a refund?

Yes! The majority of hotel bookings are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to review the best deals near Lewis and Clark Interpretive Center.

Where can I learn more about changing or cancelling my trip in the area near Lewis and Clark Interpretive Center?

For additional details about rescheduling or cancelling your stay near Lewis and Clark Interpretive Center, click here.

What can I see and do near Lewis and Clark Interpretive Center?

You might spend a leisurely day outdoors at Lewis and Clark State Memorial Park and Dads Club Park. Create some family memories at CP Pinball and Saint Louis Zoo WildCare Park. Explore nature at Jones-Confluence Point State Park and Columbia Bottom Conservation Area.

Find hotels near Lewis and Clark Interpretive Center, St. Louis from ￥11,239

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Our top choices for Lewis and Clark Interpretive Center hotels

1. Holiday Inn Express & Suites Edwardsville by IHG

2. Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

3. Comfort Inn Edwardsville - St. Louis

4. Bel Air Motel

5. TownePlace Suites by Marriott St. Louis Edwardsville, IL

6. Drury Inn & Suites St. Louis Collinsville

7. Country Hearth Inn & Suites Edwardsville St. Louis

8. Hampton Inn & Suites St. Louis-Edwardsville

9. Best Western Plus Pontoon Beach

10. Hampton Inn & Suites St. Louis/Alton

11. Holiday Inn Express Troy by IHG

12. Red Lion Inn & Suites Pontoon Beach

13. Super 8 by Wyndham Troy IL/St. Louis Area

14. Comfort Inn Collinsville near St. Louis

15. Red Roof Inn St Louis - Troy, IL

16. The Great Rivers, an Ascend Collection Hotel

17. Days Inn by Wyndham Troy IL

18. La Quinta Inn & Suites by Wyndham Pontoon Beach

19. Best Western Plus Parkway Hotel

20. DoubleTree by Hilton Collinsville - St. Louis

Compare popular hotels close to Lewis and Clark Interpretive Center

Top Lewis and Clark Interpretive Center Hotel Reviews

21C Museum Hotel St Louis

Drury Plaza Hotel St. Louis at the Arch

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hyatt Regency St. Louis at The Arch

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Home2 Suites by Hilton St. Louis Downtown

Live by Loews - St.Louis

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Super 8 by Wyndham St. Louis North

Other attractions near Lewis and Clark Interpretive Center

Lewis and Clark Confluence Tower

Lewis and Clark State Memorial Park

Hartford Park

Hartford City Hall

Jones-Confluence Point State Park

Dads Club Park

South Roxana Dad's Club Park

Frequently asked questions