Find hotels near Lake City Medical Center, Lake City from ￥9,143

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Dec 11 - Dec 12
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Dec 12 - Dec 13
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Dec 12 - Dec 14
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Our top choices for Lake City Medical Center hotels

Exterior
Tru by Hilton Lake City

Tru by Hilton Lake City

Tru by Hilton Lake City
2.5 star property
0.4 km from Lake City Medical Center
9.2 out of 10, Wonderful, (1000)
"Great place for a restful night when traveling. "
United States
Peggy
The price is ￥15,726
￥17,693 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Tru by Hilton Lake City
Lobby
Comfort Suites Lake City

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
0.7 km from Lake City Medical Center
9.6 out of 10, Exceptional, (1000)
"We love to stop here when traveling to Orlando"
United States
Bridget
The price is ￥16,047
￥18,053 total
includes taxes & fees
Dec 14 - Dec 15
Comfort Suites Lake City
Exterior
La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
2.5 star property
0.4 km from Lake City Medical Center
8.8 out of 10, Excellent, (1006)
"Very clean property and a full hot breakfast buffet! "
United States
Julie
The price is ￥14,577
￥16,399 total
includes taxes & fees
Dec 15 - Dec 16
La Quinta Inn & Suite by Wyndham Lake City
Lobby
Best Western Plus Lake City

Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
0.7 km from Lake City Medical Center
9.2 out of 10, Wonderful, (1010)
"Staff was great and breakfast was awesome."
United States
Derrick
The price is ￥13,612
￥15,313 total
includes taxes & fees
Dec 14 - Dec 15
Best Western Plus Lake City
Property amenity
Courtyard By Marriott Lake City

Courtyard By Marriott Lake City

Courtyard By Marriott Lake City
3.0 star property
0.8 km from Lake City Medical Center
9.6 out of 10, Exceptional, (176)
"Nice place for a weekend trip to the springs close by.Would definitely stay here again."
United States
Mary
The price is ￥16,664
￥18,747 total
includes taxes & fees
Dec 28 - Dec 29
Courtyard By Marriott Lake City
Lobby
Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
0.9 km from Lake City Medical Center
9.4 out of 10, Exceptional, (1001)
"It was a great stay "
United States
Miranda
The price is ￥13,581
￥15,278 total
includes taxes & fees
Dec 21 - Dec 22
Hampton Inn & Suites Lake City
Exterior
Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City

Home2 Suites by Hilton Lake City
3.0 star property
0.8 km from Lake City Medical Center
9.4 out of 10, Exceptional, (733)
"Great place to stay. We will be back. "
United States
Joseph
The price is ￥18,564
￥20,885 total
includes taxes & fees
Dec 24 - Dec 25
Home2 Suites by Hilton Lake City
BBQ/picnic area
Americas Best Value Inn Lake City

Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
0.8 km from Lake City Medical Center
8.8 out of 10, Excellent, (1000)
"We had a good stay, the room was clean, check in quick and easy, the bed was comfortable."
United States
Alan
The price is ￥9,928
￥11,169 total
includes taxes & fees
Dec 14 - Dec 15
Americas Best Value Inn Lake City
Exterior
Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
3.0 star property
0.7 km from Lake City Medical Center
8.6 out of 10, Excellent, (1000)
"Dog friendly. "
United States
Barbara
The price is ￥13,016
￥14,643 total
includes taxes & fees
Dec 14 - Dec 15
Holiday Inn & Suites Lake City by IHG
Lobby
Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
2.5 star property
1 km from Lake City Medical Center
9.0 out of 10, Wonderful, (164)
"Very clean, friendly staff, safe and quiet "
United States
Amy
The price is ￥13,957
￥15,701 total
includes taxes & fees
Jan 4 - Jan 5, 2026
Fairfield Inn & Suites Lake City
Iron/ironing board, free WiFi, bed sheets
Regal Inn

Regal Inn

Regal Inn
2.5 star property
0.8 km from Lake City Medical Center
8.6 out of 10, Excellent, (541)
"very clean room, A/C and heat work great, good TV, outstanding price, staff very friendly , next door to Waffle House, numerous Restaurants within 2 blocks ( walking ) , will be staying here more when traveling "
United States
Robert
The price is ￥9,662
￥10,869 total
includes taxes & fees
Dec 14 - Dec 15
Regal Inn
Lobby
Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center

Motel 6 – Lake City, Fl – Medical Center
2.0 star property
0.5 km from Lake City Medical Center
8.0 out of 10, Very Good, (69)
"Great little motel with extremely nice staff. "
United States
Georgiy
The price is ￥8,128
￥9,143 total
includes taxes & fees
Dec 14 - Dec 15
Motel 6 – Lake City, Fl – Medical Center
Outdoor pool, sun loungers
Quality Inn Lake City

Quality Inn Lake City

Quality Inn Lake City
2.5 star property
0.8 km from Lake City Medical Center
7.8 out of 10, Good, (952)
"very clean room, great staff, we will be staying there again when we come to see our daughter "
United States
Gary
The price is ￥10,530
￥11,846 total
includes taxes & fees
Jan 11 - Jan 12, 2026
Quality Inn Lake City
Pillowtop beds, in-room safe, desk, blackout drapes
Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
0.6 km from Lake City Medical Center
7.6 out of 10, Good, (1000)
"Clean room everything I could need staff very nice and helpful I ll be back "
United States
Daphnea
The price is ￥9,843
￥11,073 total
includes taxes & fees
Dec 16 - Dec 17
Days Inn by Wyndham Lake City I-75
Soundproofing, bed sheets
Driftwood Inn

Driftwood Inn

Driftwood Inn
2.0 star property
1.1 km from Lake City Medical Center
7.8 out of 10, Good, (754)
"Clean, quiet, comfortable. Courteous staff. Great location. Would definitely stay here again."
United States
Michelle
Driftwood Inn
Lobby
Rodeway Inn Lake City I-75

Rodeway Inn Lake City I-75

Rodeway Inn Lake City I-75
2.0 star property
0.6 km from Lake City Medical Center
6.8 out of 10, (386)
"It was near the function I was there for, including my favorite eating place. It was also near the inter state highway I travel. The price was the most reasonable and it served it's purpose. When I go back up there, I will book with them again!"
United States
Alpha
The price is ￥9,812
￥11,039 total
includes taxes & fees
Dec 17 - Dec 18
Rodeway Inn Lake City I-75
Exterior
Econo Lodge Lake City-North

Econo Lodge Lake City-North

Econo Lodge Lake City-North
2.0 star property
0.5 km from Lake City Medical Center
6.8 out of 10, (400)
"Clean rooms, friendly and helpful staff. Good value."
United States
Katharine
The price is ￥10,231
￥11,510 total
includes taxes & fees
Dec 21 - Dec 22
Econo Lodge Lake City-North
Reception
Guest Inn

Guest Inn

Guest Inn
2.0 star property
0.6 km from Lake City Medical Center
6.0 out of 10, (191)
"👍"
United States
Suren
Guest Inn
Lobby
Knights Inn Lake City

Knights Inn Lake City

Knights Inn Lake City
1.5 star property
0.8 km from Lake City Medical Center
5.4 out of 10, (637)
"Love this place!!"
United States
Kimberly
The price is ￥8,566
￥9,637 total
includes taxes & fees
Dec 13 - Dec 14
Knights Inn Lake City
Outdoor pool
Baymont by Wyndham Lake City I-75

Baymont by Wyndham Lake City I-75

Baymont by Wyndham Lake City I-75
2.5 star property
0.6 km from Lake City Medical Center
5.0 out of 10, (1004)
"The place was dated and not very well maintained most foreign owed hotels are"
United States
Buddy
The price is ￥9,001
￥10,127 total
includes taxes & fees
Dec 12 - Dec 13
Baymont by Wyndham Lake City I-75
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Lake City Medical Center Hotel Reviews

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City

10/10 Excellent
"The property was very well situated, close to the highway and gas stations. The food for breakfast was very well appointed. The check-in and checkout process was very simple."
Teresita 1-night trip
Posted 2 days ago
La Quinta Inn & Suite by Wyndham Lake City

Hotels near other Lake City Medical Center attractions

Aerial photo Waterford Lakes Town Center shopping plaza

Lake City Mall

3.8/5 (124 reviews)
You can enjoy retail therapy at Lake City Mall during your stay in Lake City. While you're in the area, stroll along the lakeside.
See properties
Columbia County Courthouse in Lake City, Florida, United States.

Columbia County Courthouse

3.5/5 (28 reviews)
Columbia County Courthouse is just one of the places to see in Lake City, so why not enjoy the other things to explore during your travels? While you're in the area, stroll along the lakeside.
See properties

Frequently asked questions

What's the area like around Lake City Medical Center?
Lake City Medical Center is located in Lake City. This family-friendly area is known for its beautiful lakeside setting and array of dining options. If you're looking for a convenient place to stay, check out the 24 hotels and other accommodations you'll find within a mile.
What's the best hotel to stay close to Lake City Medical Center?
Adjacent to Lake City Medical Center, La Quinta Inn & Suite by Wyndham Lake City is one of the top choices for your stay based on our traveler data, and this hotel offers free breakfast and an indoor pool. Other good options close by include Tru by Hilton Lake City and Best Western Plus Lake City.
How many hotels will I find near Lake City Medical Center?
Expedia has 24 hotels and other accommodations within a mile from Lake City Medical Center.
If I need to cancel the hotel reservation for my stay near Lake City Medical Center, will I receive a refund?
Yes! The majority of hotel bookings are refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view the best options available near Lake City Medical Center.
Where can I learn more about changing or cancelling my trip in the area near Lake City Medical Center?
To access more information about updating your stay near Lake City Medical Center or cancelling it, go to https://www.expedia.com/service/.
What can I see and do near Lake City Medical Center?
You might spend a leisurely day outdoors at Southside Sports Complex and Southside Recreation Complex. A trip to Lake City Mall and Lake DeSoto Farmers Market might be just the ticket for souvenir shopping. Lake City Columbia County Historical Museum, Regal UA Cinema 90, and Florida Department of Transportation are a few additional nearby sights.