La Mesa Vacation Rentals

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
Jun 5 - Jun 7
In two months
Jul 17 - Jul 19
In three months
Aug 14 - Aug 16
In four months
Sep 11 - Sep 13

Our top choices for La Mesa vacation rentals

50-inch LED TV with satellite channels

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.2 out of 10, Wonderful, (291 reviews)
"Very good place to stay and safe place..!"
United States
Somnueg
The price is ￥19,060
￥29,352 total
includes taxes & fees
May 22 - May 23
Arcadia Condo Suites
Interior

LILIA HOUSE 10 MINUTES AIRPORT

LILIA HOUSE 10 MINUTES AIRPORT
Panamá
8.0 out of 10, Very Good, (1 review)
The price is ￥7,942
￥13,342 total
includes taxes & fees
May 22 - May 23
LILIA HOUSE 10 MINUTES AIRPORT
Property grounds

Balboa Village

Balboa Village
Panamá
6.0 out of 10, (1 review)
"It was okay. unfortunately there was no internet! "
Canada
Yuro
The price is ￥8,005
￥13,331 total
includes taxes & fees
May 22 - May 23
Balboa Village
1 bedroom, iron/ironing board, WiFi, bed sheets

Charming modern studio!

Charming modern studio!
Parque Lefevre
9.0 out of 10, Wonderful, (2 reviews)
"The space was nice and cozy.I would definitely recommend for a prefect stay"
United States
Kimberly
The price is ￥6,433
￥12,786 total
includes taxes & fees
May 29 - May 30
Charming modern studio!
Terrace/patio

Cozy and Safe Environment Close to the Airport.

Cozy and Safe Environment Close to the Airport.
Panamá
The price is ￥9,863
￥13,040 total
includes taxes & fees
Jun 2 - Jun 3
Cozy and Safe Environment Close to the Airport.
3 bedrooms, desk, WiFi, bed sheets

Apartamento a Solo 15 Minutos del Aeropuerto con Piscina

Apartamento a Solo 15 Minutos del Aeropuerto con Piscina
Juan Diaz
The price is ￥14,152
￥22,715 total
includes taxes & fees
May 22 - May 23
Apartamento a Solo 15 Minutos del Aeropuerto con Piscina
Outdoor pool

Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
3.5 star property
San Francisco
8.0 out of 10, Very Good, (11 reviews)
"Amazing! Great staff and wonderful high top views. "
United States
Krysta Alicia
The price is ￥21,480
￥23,628 total
includes taxes & fees
May 22 - May 23
Dovle Residences by HMS-Preferred Member
Apartment (17F) | Living area | TV

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
8.0 out of 10, Very Good, (1 review)
"Review checkin process. Find entry codes and details about key fobs. Find out if there is construction next door as i was awaken every morning at 7am by construction noise. Verify everything works upon entry and request immediate fix. I was without internet for a day and had to wait various days for repairmen to come fix things without having a set time for their visit. Great place to stay. Walking distance of many things and great amenities but had some minor inconveniences. Staff was very...
United States
Will
The price is ￥7,731
￥32,946 total
includes taxes & fees
May 24 - May 25
Living 73 Panamá by Boutique Apartments
Apartment | 1 bedroom

Cozy Urban Loft 1br Near Coast

Cozy Urban Loft 1br Near Coast
2.0 star property
San Francisco
The price is ￥26,005
￥34,056 total
includes taxes & fees
May 23 - May 24
Cozy Urban Loft 1br Near Coast
Exterior detail

Cozy Apt+WiFi+Kitchen+AC+Laundry+TV+Parking@Panamá

Cozy Apt+WiFi+Kitchen+AC+Laundry+TV+Parking@Panamá
Parque Lefevre
The price is ￥7,147
￥10,824 total
includes taxes & fees
May 27 - May 28
Cozy Apt+WiFi+Kitchen+AC+Laundry+TV+Parking@Panamá
Interior

w* | Pleasant 1BR in San Francisco

w* | Pleasant 1BR in San Francisco
San Francisco
10.0 out of 10, Exceptional, (1 review)
"Location, location, location is the first asset to call out. Second, the condition of the unit was spotless. Third, the front desk staff and building security team were welcoming and friendly. This is now our “go to” destination when we travel to Panama. Thank you."
United States
Richard B.
The price is ￥12,706
￥20,965 total
includes taxes & fees
Jun 2 - Jun 3
w* | Pleasant 1BR in San Francisco
Interior

w* | Prestigious 1BR in San Francisco

w* | Prestigious 1BR in San Francisco
San Francisco
10.0 out of 10, Exceptional, (1 review)
"Everything was as described. Restaurants were conveniently located. View was an added bonus and was better than pictured. We were able to enjoy the gym. The pool was a little cool but still enjoyable. Would recommend this host."
United States
Ruben O.
The price is ￥13,183
￥20,330 total
includes taxes & fees
Jun 2 - Jun 3
w* | Prestigious 1BR in San Francisco
Pool

Luxury 2 bedroom apt free parking and Pool

Luxury 2 bedroom apt free parking and Pool
San Francisco
10.0 out of 10, Exceptional, (2 reviews)
"Lorenzo, the host was very responsive to my emails, and communication about the unit was very clear. The apartment was clean and spacious. The air conditioners worked perfectly. The condo is in a good location, a few blocks from a couple of supermarkets. Having a washer & dryer was a plus. If you're facing the building from the street, the concierge/office is in the front on the bottom floor. I had difficulty recognizing the concierge office at night at time of checkin. If you're facing the...
United States
Ernie P.
The price is ￥7,697
￥24,240 total
includes taxes & fees
May 21 - May 22
Luxury 2 bedroom apt free parking and Pool
Pool

Apt 2 bedroom free parking and pool

Apt 2 bedroom free parking and pool
San Francisco
8.0 out of 10, Very Good, (1 review)
"Very good. Excellent location."
Canada
FRANCOIS
The price is ￥7,697
￥24,240 total
includes taxes & fees
May 21 - May 22
Apt 2 bedroom free parking and pool
Fridge, microwave, stovetop, dishwasher

w* | Versatile 1BR w/ Balcony in Panama

w* | Versatile 1BR w/ Balcony in Panama
Rio Abajo
The price is ￥11,453
￥20,202 total
includes taxes & fees
May 25 - May 26
w* | Versatile 1BR w/ Balcony in Panama
Apartment, 3 Bedrooms | Living area | 32-inch Smart TV with digital channels, TV, Netflix

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.6 out of 10, Good, (195 reviews)
"Nice place to stay I always enjoy my stay highly recommended.."
United States
Anecia
The price is ￥6,844
￥29,830 total
includes taxes & fees
May 21 - May 22
Boutique Apartments Panamá Coco del Mar
Exterior

Tranquil cabin with WiFi in Los Altos de Cerro Azul

Tranquil cabin with WiFi in Los Altos de Cerro Azul
Los Altos de Cerro Azul
The price is ￥23,825
￥32,561 total
includes taxes & fees
May 27 - May 28
Tranquil cabin with WiFi in Los Altos de Cerro Azul
Pool

Hummingbird House/Casa de Colibri

Hummingbird House/Casa de Colibri
Panamá
The price is ￥39,708
￥51,461 total
includes taxes & fees
May 22 - May 23
Hummingbird House/Casa de Colibri
Apartment | 1 bedroom, Internet

w Engaging 1BR w Balcony in San Francisco

w Engaging 1BR w Balcony in San Francisco
2.0 star property
San Francisco
The price is ￥17,454
￥24,353 total
includes taxes & fees
Jun 2 - Jun 3
w Engaging 1BR w Balcony in San Francisco
Apartment, 1 Bedroom, Balcony | Property grounds

Swette Love 10 Minutes From the Airport Tocumen

Swette Love 10 Minutes From the Airport Tocumen
2.0 star property
Las Mañanitas
The price is ￥9,233
￥12,003 total
includes taxes & fees
May 24 - May 25
Swette Love 10 Minutes From the Airport Tocumen
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top La Mesa Hotel Reviews

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica

10/10 Excellent
"Breakfast was adequate"
ray 1-night trip
Posted 2 hours ago
Ramada Plaza by Wyndham Panama Punta Pacifica

Find out more about La Mesa

Search for holiday rentals in La Mesa on Expedia! You can easily find your home rentals, villas, holiday apartments in La Mesa using one of the methods below:

  • View our selection of featured holiday rentals in La Mesa
  • Use the map to find apartments and other holiday homes in the La Mesa neighbourhood you prefer
  • Enter your travel dates to view the best deals on holiday rentals in La Mesa while they last

Look no further and take a look at our great range of rental properties in La Mesa!

Frequently asked questions

Are there vacation rentals in La Mesa?

Yes, we offer vacation rentals close to well known sights in La Mesa, or you can choose a more secluded option if you're looking for a relaxing stay.

What's the top vacation rental in La Mesa?

Cozy 3-bedroom townhome with WiFi, AC in fabulous Panamá: Visitors like this La Mesa vacation home rental. It is equipped with a selection of books, air-conditioning, and laundry facilities to help you feel comfortable during your stay. It has 3 bedrooms as well as a kitchen with a fridge, an oven, and a microwave, so you can cook with friends or family.

What’s there to see and do in La Mesa?

While exploring the area, visit family-friendly sights like Chepo Youth Recreation Center, or get outside and enjoy nature at Chagres National Park. In the larger area, you’ll find Metromall Panama and Los Pueblos Commercial Center.

What’s a vacation rental in La Mesa like?

A vacation rental is a private property you can stay in for short or long periods in La Mesa. Vacation rentals feature amenities such as hot tubs, fire pits, and patios so your stay will be comfortable. If you're concerned about a sanitized environment, vacation rentals can offer a sense of security away from public hotel elevators and busy concierge desks while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a popular option for family trips or small group gatherings.